(5 nodes) Jagged/Serrate protein, and Notch network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	notch2	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2. (2532 aa)
	LOC106522408	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1253 aa)
	rbpj	Recombining binding protein suppressor of hairless. (301 aa)
	LOC106528756	Neurogenic locus notch homolog protein 1-like. (2518 aa)
	LOC106531532	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1237 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106522408	LOC106528756	A0A2I4BT18	A0A2I4CHJ2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1-like.	0.976
LOC106522408	notch2	A0A2I4BT18	A0A2I4AX98	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.	0.952
LOC106522408	rbpj	A0A2I4BT18	A0A2I4BV43	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless.	0.480
LOC106528756	LOC106522408	A0A2I4CHJ2	A0A2I4BT18	Neurogenic locus notch homolog protein 1-like.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.976
LOC106528756	LOC106531532	A0A2I4CHJ2	A0A2I4CSA2	Neurogenic locus notch homolog protein 1-like.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.976
LOC106528756	rbpj	A0A2I4CHJ2	A0A2I4BV43	Neurogenic locus notch homolog protein 1-like.	Recombining binding protein suppressor of hairless.	0.983
LOC106531532	LOC106528756	A0A2I4CSA2	A0A2I4CHJ2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1-like.	0.976
LOC106531532	notch2	A0A2I4CSA2	A0A2I4AX98	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.	0.952
LOC106531532	rbpj	A0A2I4CSA2	A0A2I4BV43	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless.	0.480
notch2	LOC106522408	A0A2I4AX98	A0A2I4BT18	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.952
notch2	LOC106531532	A0A2I4AX98	A0A2I4CSA2	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.952
notch2	rbpj	A0A2I4AX98	A0A2I4BV43	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.	Recombining binding protein suppressor of hairless.	0.973
rbpj	LOC106522408	A0A2I4BV43	A0A2I4BT18	Recombining binding protein suppressor of hairless.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.480
rbpj	LOC106528756	A0A2I4BV43	A0A2I4CHJ2	Recombining binding protein suppressor of hairless.	Neurogenic locus notch homolog protein 1-like.	0.983
rbpj	LOC106531532	A0A2I4BV43	A0A2I4CSA2	Recombining binding protein suppressor of hairless.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.480
rbpj	notch2	A0A2I4BV43	A0A2I4AX98	Recombining binding protein suppressor of hairless.	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.	0.973