(30 nodes) Mixed, incl. Homeobox protein SIX1, N-terminal SD domain, and EYA domain network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	otx1	Homeobox protein OTX1. (417 aa)
	dlx3	Homeobox protein DLX-3. (278 aa)
	LOC106511357	Homeobox protein Dlx4b-like. (335 aa)
	pax6	Paired box protein Pax-6. (449 aa)
	eya1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (614 aa)
	atoh1	Protein atonal homolog 1. (341 aa)
	pax7	Paired box protein Pax-7. (508 aa)
	vax1	Ventral anterior homeobox 1. (313 aa)
	pax8	Paired box protein Pax-8 isoform X1. (459 aa)
	LOC106515362	Paired box protein Pax-2-A-like isoform X1. (485 aa)
	rp9	Retinitis pigmentosa 9 protein. (224 aa)
	foxi2	Forkhead box protein I2. (372 aa)
	LOC106516626	Homeobox protein SIX3. (277 aa)
	LOC106516869	Retinal homeobox protein Rx2. (328 aa)
	LOC106517645	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (476 aa)
	LOC106518786	Solute carrier family 2, facilitated glucose transporter member 9-like; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (512 aa)
	six6	Homeobox protein SIX6. (245 aa)
	LOC106523847	Dachshund homolog 1-like. (655 aa)
	LOC106524542	Homeobox protein Hox-B1a-like. (142 aa)
	eya4	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (650 aa)
	pou4f3	POU domain protein. (351 aa)
	LOC106527845	Homeobox protein six1a-like. (228 aa)
	LOC106527841	Homeobox protein SIX5-like. (927 aa)
	LOC106528123	Dachshund homolog 1-like isoform X1. (628 aa)
	rlbp1	Retinaldehyde-binding protein 1. (307 aa)
	LOC106530185	Forkhead box protein E4-like. (411 aa)
	tgfbi	Transforming growth factor-beta-induced protein ig-h3. (684 aa)
	six2	Homeobox protein SIX2. (290 aa)
	six3	Homeobox protein SIX3. (294 aa)
	six1	Homeobox protein SIX1. (284 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511357	foxi2	A0A2I4AJB1	A0A2I4B3V1	Homeobox protein Dlx4b-like.	Forkhead box protein I2.	0.615
LOC106511357	pax8	A0A2I4AJB1	A0A2I4AUH2	Homeobox protein Dlx4b-like.	Paired box protein Pax-8 isoform X1.	0.408
LOC106515362	dlx3	A0A2I4AYM3	A0A2I4AJ98	Paired box protein Pax-2-A-like isoform X1.	Homeobox protein DLX-3.	0.407
LOC106515362	foxi2	A0A2I4AYM3	A0A2I4B3V1	Paired box protein Pax-2-A-like isoform X1.	Forkhead box protein I2.	0.413
LOC106515362	vax1	A0A2I4AYM3	A0A2I4AS88	Paired box protein Pax-2-A-like isoform X1.	Ventral anterior homeobox 1.	0.687
LOC106516626	LOC106517645	A0A2I4B460	A0A2I4B8M5	Homeobox protein SIX3.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.534
LOC106516626	eya1	A0A2I4B460	A0A2I4AQK4	Homeobox protein SIX3.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.534
LOC106516626	eya4	A0A2I4B460	A0A2I4C2Z3	Homeobox protein SIX3.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.534
LOC106516626	pax6	A0A2I4B460	A0A2I4AP93	Homeobox protein SIX3.	Paired box protein Pax-6.	0.669
LOC106516869	LOC106518786	A0A2I4B574	A0A2I4BD32	Retinal homeobox protein Rx2.	Solute carrier family 2, facilitated glucose transporter member 9-like; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.632
LOC106516869	six3	A0A2I4B574	A0A2I4CZC7	Retinal homeobox protein Rx2.	Homeobox protein SIX3.	0.633
LOC106517645	LOC106516626	A0A2I4B8M5	A0A2I4B460	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX3.	0.534
LOC106517645	LOC106523847	A0A2I4B8M5	A0A2I4BYQ7	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Dachshund homolog 1-like.	0.487
LOC106517645	LOC106527841	A0A2I4B8M5	A0A2I4CE86	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX5-like.	0.593
LOC106517645	LOC106527845	A0A2I4B8M5	A0A2I4CE78	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein six1a-like.	0.593
LOC106517645	LOC106528123	A0A2I4B8M5	A0A2I4CF96	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Dachshund homolog 1-like isoform X1.	0.487
LOC106517645	rp9	A0A2I4B8M5	A0A2I4B065	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Retinitis pigmentosa 9 protein.	0.654
LOC106517645	six1	A0A2I4B8M5	A0A2I4D9S0	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX1.	0.602
LOC106517645	six2	A0A2I4B8M5	A0A2I4CYZ5	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX2.	0.593
LOC106517645	six3	A0A2I4B8M5	A0A2I4CZC7	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX3.	0.534