(28 nodes) Chemokine receptors bind chemokines, and Inflammatory response network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cxcl14	C-X-C motif chemokine 14. (98 aa)
	LOC106514188	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	LOC106514244	C-C chemokine receptor type 1-like isoform X1; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	LOC106516879	C-C motif chemokine 21c-like. (110 aa)
	LOC106517490	C-C chemokine receptor type 9-like; Belongs to the G-protein coupled receptor 1 family. (365 aa)
	LOC106520002	C-C motif chemokine 4-like. (107 aa)
	LOC106520939	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (105 aa)
	LOC106520938	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (121 aa)
	ackr4	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	LOC106521077	C-X-C motif chemokine 5-like isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (187 aa)
	LOC106521577	C-C motif chemokine 25-like. (154 aa)
	LOC106521844	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (108 aa)
	LOC106522010	C-C chemokine receptor type 7-like; Belongs to the G-protein coupled receptor 1 family. (392 aa)
	LOC106522252	C-X-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family. (388 aa)
	LOC106522254	C-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	LOC106522573	LOW QUALITY PROTEIN: C-X-C chemokine receptor type 4-like; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	cxcr5	C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	cxcl12	Stromal cell-derived factor 1 isoform X1. (99 aa)
	LOC106524505	Atypical chemokine receptor 4-like; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	LOC106524551	C-X-C motif chemokine. (102 aa)
	LOC106525440	C-C motif chemokine 4-like. (109 aa)
	LOC106525716	C-X-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	cxcr4	C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (381 aa)
	LOC106526779	C-C chemokine receptor type 9-like; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	ccr7	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (560 aa)
	LOC106530437	C-X-C motif chemokine. (105 aa)
	ackr3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	LOC106536276	C-C motif chemokine 3-like. (94 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106514188	LOC106514244	A0A2I4ATF9	A0A2I4ATN7	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C chemokine receptor type 1-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.629
LOC106514188	LOC106517490	A0A2I4ATF9	A0A2I4B7X7	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C chemokine receptor type 9-like; Belongs to the G-protein coupled receptor 1 family.	0.460
LOC106514188	LOC106520002	A0A2I4ATF9	A0A2I4BHY8	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine 4-like.	0.722
LOC106514188	LOC106520938	A0A2I4ATF9	A0A2I4BLY0	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.	0.552
LOC106514188	LOC106521077	A0A2I4ATF9	A0A2I4BMI9	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine 5-like isoform X1; Belongs to the intercrine alpha (chemokine CxC) family.	0.586
LOC106514188	LOC106521577	A0A2I4ATF9	A0A2I4BPM6	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine 25-like.	0.537
LOC106514188	LOC106522010	A0A2I4ATF9	A0A2I4BRC6	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C chemokine receptor type 7-like; Belongs to the G-protein coupled receptor 1 family.	0.472
LOC106514188	LOC106522252	A0A2I4ATF9	A0A2I4BSB4	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-X-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	0.455
LOC106514188	LOC106522254	A0A2I4ATF9	A0A2I4BSG0	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family.	0.455
LOC106514188	LOC106522573	A0A2I4ATF9	A0A2I4BTK5	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	LOW QUALITY PROTEIN: C-X-C chemokine receptor type 4-like; Belongs to the G-protein coupled receptor 1 family.	0.635
LOC106514188	LOC106525440	A0A2I4ATF9	A0A2I4C566	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine 4-like.	0.579
LOC106514188	LOC106525716	A0A2I4ATF9	A0A2I4C684	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-X-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	0.455
LOC106514188	LOC106526779	A0A2I4ATF9	A0A2I4CA94	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C chemokine receptor type 9-like; Belongs to the G-protein coupled receptor 1 family.	0.460
LOC106514188	LOC106536276	A0A2I4ATF9	A0A2I4D9M2	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine 3-like.	0.435
LOC106514188	ackr3	A0A2I4ATF9	A0A2I4CVB6	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.403
LOC106514188	ccr7	A0A2I4ATF9	A0A2I4CAQ9	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	0.440
LOC106514188	cxcl12	A0A2I4ATF9	A0A2I4BZL4	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	Stromal cell-derived factor 1 isoform X1.	0.586
LOC106514188	cxcr4	A0A2I4ATF9	A0A2I4C6D6	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family.	0.635
LOC106514188	cxcr5	A0A2I4ATF9	A0A2I4BUC8	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.514
LOC106514244	LOC106514188	A0A2I4ATN7	A0A2I4ATF9	C-C chemokine receptor type 1-like isoform X1; Belongs to the G-protein coupled receptor 1 family.	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.	0.629