23 items (Austrofundulus limnaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106512962	E3 SUMO-protein ligase PIAS1-like isoform X1. (698 aa)
	LOC106515271	Small ubiquitin-related modifier. (96 aa)
	LOC106517370	SUMO-conjugating enzyme UBC9-B; Belongs to the ubiquitin-conjugating enzyme family. (138 aa)
	LOC106518458	Small ubiquitin-related modifier. (94 aa)
	LOC106518463	Sentrin-specific protease 2-like isoform X2. (610 aa)
	ranbp2	E3 SUMO-protein ligase RanBP2. (3036 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa)
	ube2i	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	rangap1	Ran GTPase-activating protein 1 isoform X1. (588 aa)
	LOC106521199	E3 SUMO-protein ligase PIAS1-like isoform X1. (679 aa)
	LOC106521991	BTB/POZ domain-containing protein KCTD5-like. (265 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	LOC106522768	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (269 aa)
	LOC106523318	Small ubiquitin-related modifier. (94 aa)
	senp6	Sentrin-specific protease 6. (1057 aa)
	LOC106524707	Sentrin-specific protease 1-like isoform X1. (727 aa)
	senp7	Sentrin-specific protease 7 isoform X1. (822 aa)
	LOC106527146	Uncharacterized protein LOC106527146. (1048 aa)
	senp5	Sentrin-specific protease 5 isoform X1. (593 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	LOC106534320	E3 SUMO-protein ligase PIAS2-like. (558 aa)
	sae1	SUMO-activating enzyme subunit 1. (345 aa)
	nfatc2ip	NFATC2-interacting protein. (327 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106512962	LOC106515271	A0A2I4ANE1	A0A2I4AY68	E3 SUMO-protein ligase PIAS1-like isoform X1.	Small ubiquitin-related modifier.	0.751
LOC106512962	LOC106517370	A0A2I4ANE1	A0A2I4B789	E3 SUMO-protein ligase PIAS1-like isoform X1.	SUMO-conjugating enzyme UBC9-B; Belongs to the ubiquitin-conjugating enzyme family.	0.801
LOC106512962	LOC106518458	A0A2I4ANE1	A0A2I4BBU9	E3 SUMO-protein ligase PIAS1-like isoform X1.	Small ubiquitin-related modifier.	0.751
LOC106512962	LOC106521991	A0A2I4ANE1	A0A2I4BR74	E3 SUMO-protein ligase PIAS1-like isoform X1.	BTB/POZ domain-containing protein KCTD5-like.	0.783
LOC106512962	LOC106523318	A0A2I4ANE1	A0A2I4BWR1	E3 SUMO-protein ligase PIAS1-like isoform X1.	Small ubiquitin-related modifier.	0.751
LOC106512962	nfatc2ip	A0A2I4ANE1	A0A2I4D7E0	E3 SUMO-protein ligase PIAS1-like isoform X1.	NFATC2-interacting protein.	0.608
LOC106512962	sae1	A0A2I4ANE1	A0A2I4D6F0	E3 SUMO-protein ligase PIAS1-like isoform X1.	SUMO-activating enzyme subunit 1.	0.445
LOC106512962	sumo1	A0A2I4ANE1	A0A2I4CS05	E3 SUMO-protein ligase PIAS1-like isoform X1.	Small ubiquitin-related modifier.	0.878
LOC106512962	sumo2	A0A2I4ANE1	A0A2I4BRK8	E3 SUMO-protein ligase PIAS1-like isoform X1.	Small ubiquitin-related modifier.	0.751
LOC106512962	uba2	A0A2I4ANE1	A0A2I4BIX3	E3 SUMO-protein ligase PIAS1-like isoform X1.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.443
LOC106512962	ube2i	A0A2I4ANE1	A0A2I4BKP4	E3 SUMO-protein ligase PIAS1-like isoform X1.	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.801
LOC106515271	LOC106512962	A0A2I4AY68	A0A2I4ANE1	Small ubiquitin-related modifier.	E3 SUMO-protein ligase PIAS1-like isoform X1.	0.751
LOC106515271	LOC106517370	A0A2I4AY68	A0A2I4B789	Small ubiquitin-related modifier.	SUMO-conjugating enzyme UBC9-B; Belongs to the ubiquitin-conjugating enzyme family.	0.984
LOC106515271	LOC106518463	A0A2I4AY68	A0A2I4BBY2	Small ubiquitin-related modifier.	Sentrin-specific protease 2-like isoform X2.	0.836
LOC106515271	LOC106521199	A0A2I4AY68	A0A2I4BMY6	Small ubiquitin-related modifier.	E3 SUMO-protein ligase PIAS1-like isoform X1.	0.855
LOC106515271	LOC106521991	A0A2I4AY68	A0A2I4BR74	Small ubiquitin-related modifier.	BTB/POZ domain-containing protein KCTD5-like.	0.801
LOC106515271	LOC106522768	A0A2I4AY68	A0A2I4BUE9	Small ubiquitin-related modifier.	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.	0.635
LOC106515271	LOC106524707	A0A2I4AY68	A0A2I4C256	Small ubiquitin-related modifier.	Sentrin-specific protease 1-like isoform X1.	0.836
LOC106515271	LOC106527146	A0A2I4AY68	A0A2I4CBM4	Small ubiquitin-related modifier.	Uncharacterized protein LOC106527146.	0.703
LOC106515271	LOC106534320	A0A2I4AY68	A0A2I4D2C0	Small ubiquitin-related modifier.	E3 SUMO-protein ligase PIAS2-like.	0.751