STRINGSTRING
blm blm ppargc1a ppargc1a klhl20 klhl20 nsmce2 nsmce2 LOC106511400 LOC106511400 tdp2 tdp2 LOC106515960 LOC106515960 rb1 rb1 LOC106516406 LOC106516406 ciita ciita LOC106516655 LOC106516655 topbp1 topbp1 atrx atrx mtor mtor daxx daxx LOC106519764 LOC106519764 top3a top3a LOC106521380 LOC106521380 LOC106521543 LOC106521543 LOC106522814 LOC106522814 LOC106522812 LOC106522812 mlip mlip LOC106523505 LOC106523505 tp53inp2 tp53inp2 chfr chfr nfe2 nfe2 tp53inp1 tp53inp1 ankrd1 ankrd1 rfwd3 rfwd3 rpain rpain wdfy3 wdfy3 smc5 smc5 trim8 trim8 sirt1 sirt1 ski ski LOC106527012 LOC106527012 casp8ap2 casp8ap2 patl1 patl1 morc3 morc3 rad51 rad51 sumo1 sumo1 rnf111 rnf111 LOC106532717 LOC106532717 LOC106533213 LOC106533213 sqstm1 sqstm1 rnf4 rnf4 LOC106533322 LOC106533322 usp7 usp7 atr atr LOC106534711 LOC106534711 LOC106534929 LOC106534929 topors topors LOC106536045 LOC106536045 chek2 chek2 LOC106537309 LOC106537309 LOC106512628 LOC106512628
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
blmBloom syndrome protein isoform X1. (1417 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (1002 aa)
klhl20Kelch-like protein 20. (604 aa)
nsmce2E3 SUMO-protein ligase NSE2. (229 aa)
LOC106511400NEDD4-binding protein 1-like. (838 aa)
tdp2tyrosyl-DNA phosphodiesterase 2 isoform X1. (360 aa)
LOC106515960Acidic repeat-containing protein-like. (570 aa)
rb1Retinoblastoma-associated protein. (915 aa)
LOC106516406Transcriptional regulator ATRX-like isoform X1. (1906 aa)
ciitaMHC class II transactivator. (1514 aa)
LOC106516655Probable E3 ubiquitin-protein ligase TRIM8. (588 aa)
topbp1DNA topoisomerase 2-binding protein 1. (1505 aa)
atrxTranscriptional regulator ATRX. (2185 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
daxxDeath domain-associated protein 6. (746 aa)
LOC106519764Structural maintenance of chromosomes protein 6-like. (1099 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1014 aa)
LOC106521380Protein PAT1 homolog 2-like. (709 aa)
LOC106521543Structural maintenance of chromosomes protein 6-like. (756 aa)
LOC106522814G/T mismatch-specific thymine DNA glycosylase-like isoform X1. (385 aa)
LOC106522812G/T mismatch-specific thymine DNA glycosylase-like. (452 aa)
mlipMuscular LMNA-interacting protein isoform X1. (826 aa)
LOC106523505Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (665 aa)
tp53inp2Tumor protein p53-inducible nuclear protein 2 isoform X1. (314 aa)
chfrE3 ubiquitin-protein ligase CHFR. (645 aa)
nfe2Transcription factor NF-E2 45 kDa subunit. (487 aa)
tp53inp1Tumor protein p53-inducible nuclear protein 1. (289 aa)
ankrd1Ankyrin repeat domain-containing protein 1. (312 aa)
rfwd3E3 ubiquitin-protein ligase RFWD3. (705 aa)
rpainRPA-interacting protein. (229 aa)
wdfy3WD repeat and FYVE domain-containing protein 3 isoform X1. (3590 aa)
smc5Structural maintenance of chromosomes protein 5. (1077 aa)
trim8Probable E3 ubiquitin-protein ligase TRIM8. (563 aa)
sirt1NAD-dependent protein deacetylase sirtuin-1. (690 aa)
skiSki oncogene. (725 aa)
LOC106527012tyrosyl-DNA phosphodiesterase 2-like. (298 aa)
casp8ap2CASP8-associated protein 2. (1772 aa)
patl1Protein PAT1 homolog 1. (783 aa)
morc3MORC family CW-type zinc finger protein 3 isoform X1. (1018 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
rnf111LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Arkadia. (1015 aa)
LOC1065327174-hydroxy-2-oxoglutarate aldolase, mitochondrial-like. (75 aa)
LOC106533213Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (601 aa)
sqstm1Sequestosome-1 isoform X1. (423 aa)
rnf4E3 ubiquitin-protein ligase RNF4 isoform X1. (229 aa)
LOC106533322Structural maintenance of chromosomes protein 6-like. (1091 aa)
usp7Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family. (1103 aa)
atrSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2609 aa)
LOC106534711NEDD4-binding protein 1-like. (274 aa)
LOC106534929Structural maintenance of chromosomes protein 6-like. (1099 aa)
toporsE3 ubiquitin-protein ligase Topors. (791 aa)
LOC106536045Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D-like. (640 aa)
chek2Serine/threonine-protein kinase Chk2. (537 aa)
LOC106537309Transcriptional regulator ATRX-like. (889 aa)
LOC106512628NEDD4-binding protein 1-like. (137 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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