(24 nodes) Peptide hormone secretion network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hnf1a	Hepatocyte nuclear factor 1-alpha. (561 aa)
	hnf1b	Hepatocyte nuclear factor 1-beta. (561 aa)
	vip	VIP peptides. (152 aa)
	ccdc186	Coiled-coil domain-containing protein 186 isoform X1. (1022 aa)
	slc16a2	Monocarboxylate transporter 8. (550 aa)
	LOC106526166	Rap guanine nucleotide exchange factor 4-like. (996 aa)
	LOC106520336	Protein piccolo-like isoform X1. (7620 aa)
	LOC106511293	Glucagon family neuropeptides-like isoform X1. (257 aa)
	adcyap1	Pituitary adenylate cyclase-activating polypeptide. (140 aa)
	LOC106533179	Aquaporin-1-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	snx19	Sorting nexin-19. (949 aa)
	ghsr	Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	LOC106516350	Sorting nexin-19-like isoform X1. (893 aa)
	LOC106511548	Complexin-3-like. (120 aa)
	LOC106512730	Glucagon family neuropeptides-like. (175 aa)
	LOC106512861	Rap guanine nucleotide exchange factor 4-like. (1050 aa)
	park7	Protein deglycase DJ-1. (189 aa)
	LOC106533171	Aquaporin FA-CHIP-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (280 aa)
	LOC106514760	Protein piccolo-like isoform X1. (4068 aa)
	gpr119	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (409 aa)
	LOC106530482	Complexin-3-like. (112 aa)
	LOC106530112	Endothelin-3-like. (219 aa)
	LOC106530102	Free fatty acid receptor 3-like. (323 aa)
	stxbp3	Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511293	LOC106512730	A0A2I4AJ45	A0A2I4AMR1	Glucagon family neuropeptides-like isoform X1.	Glucagon family neuropeptides-like.	0.901
LOC106511293	adcyap1	A0A2I4AJ45	A0A2I4C1C4	Glucagon family neuropeptides-like isoform X1.	Pituitary adenylate cyclase-activating polypeptide.	0.901
LOC106512730	LOC106511293	A0A2I4AMR1	A0A2I4AJ45	Glucagon family neuropeptides-like.	Glucagon family neuropeptides-like isoform X1.	0.901
LOC106512730	adcyap1	A0A2I4AMR1	A0A2I4C1C4	Glucagon family neuropeptides-like.	Pituitary adenylate cyclase-activating polypeptide.	0.900
LOC106512861	LOC106526166	A0A2I4AMX6	A0A2I4C810	Rap guanine nucleotide exchange factor 4-like.	Rap guanine nucleotide exchange factor 4-like.	0.901
LOC106526166	LOC106512861	A0A2I4C810	A0A2I4AMX6	Rap guanine nucleotide exchange factor 4-like.	Rap guanine nucleotide exchange factor 4-like.	0.901
LOC106530102	gpr119	A0A2I4CMB1	A0A2I4CNX1	Free fatty acid receptor 3-like.	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	0.504
LOC106530112	ghsr	A0A2I4CMD1	A0A2I4C5N5	Endothelin-3-like.	Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.477
adcyap1	LOC106511293	A0A2I4C1C4	A0A2I4AJ45	Pituitary adenylate cyclase-activating polypeptide.	Glucagon family neuropeptides-like isoform X1.	0.901
adcyap1	LOC106512730	A0A2I4C1C4	A0A2I4AMR1	Pituitary adenylate cyclase-activating polypeptide.	Glucagon family neuropeptides-like.	0.900
ghsr	LOC106530112	A0A2I4C5N5	A0A2I4CMD1	Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Endothelin-3-like.	0.477
gpr119	LOC106530102	A0A2I4CNX1	A0A2I4CMB1	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	Free fatty acid receptor 3-like.	0.504