(27 nodes) Osteoclast differentiation network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106511478	ephrin-A2-like; Belongs to the ephrin family. (163 aa)
	lrrk1	Leucine-rich repeat serine/threonine-protein kinase 1. (1539 aa)
	LOC106511186	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family. (263 aa)
	LOC106511442	Leucine-rich repeat serine/threonine-protein kinase 1-like. (711 aa)
	LOC106511793	Leucine-rich repeat serine/threonine-protein kinase 1-like. (549 aa)
	LOC106512030	Proto-oncogene tyrosine-protein kinase Src-like. (251 aa)
	tcta	T-cell leukemia translocation-altered gene protein homolog. (101 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily member 11A. (647 aa)
	LOC106517855	Transcription factor jun-B-like. (330 aa)
	ostm1	Osteopetrosis-associated transmembrane protein 1. (313 aa)
	gab2	GRB2-associated-binding protein 2 isoform X1. (674 aa)
	LOC106522055	Extracellular serine/threonine protein kinase FAM20C-like. (573 aa)
	ocstamp	Osteoclast stimulatory transmembrane protein. (473 aa)
	LOC106523044	Uncharacterized protein LOC106523044 isoform X1. (272 aa)
	dcstamp	Dendritic cell-specific transmembrane protein isoform X1. (482 aa)
	glo1	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
	LOC106525162	Extracellular serine/threonine protein kinase FAM20C-like. (567 aa)
	nf1	Neurofibromin isoform X1. (2016 aa)
	LOC106526652	ephrin-A2-like isoform X1; Belongs to the ephrin family. (205 aa)
	LOC106526938	Transcription factor jun-B-like isoform X1. (332 aa)
	LOC106528116	G-protein coupled receptor 183-like; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	LOC106528117	G-protein coupled receptor 183-like; Belongs to the G-protein coupled receptor 1 family. (343 aa)
	LOC106529655	Transforming growth factor beta-1-like. (474 aa)
	src	Tyrosine-protein kinase. (550 aa)
	LOC106533687	V-type proton ATPase subunit S1-like. (485 aa)
	LOC106534650	Neurofibromin. (2131 aa)
	LOC106535376	V-type proton ATPase subunit S1-like. (448 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511186	LOC106523044	A0A2I4AIS2	A0A2I4BVK5	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Uncharacterized protein LOC106523044 isoform X1.	0.591
LOC106511186	dcstamp	A0A2I4AIS2	A0A2I4BXX7	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Dendritic cell-specific transmembrane protein isoform X1.	0.561
LOC106511186	ostm1	A0A2I4AIS2	A0A2I4BCJ2	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Osteopetrosis-associated transmembrane protein 1.	0.407
LOC106511186	tnfrsf11a	A0A2I4AIS2	A0A2I4B840	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily member 11A.	0.998
LOC106512030	src	A0A2I4AKZ9	A0A2I4CZY8	Proto-oncogene tyrosine-protein kinase Src-like.	Tyrosine-protein kinase.	0.901
LOC106523044	LOC106511186	A0A2I4BVK5	A0A2I4AIS2	Uncharacterized protein LOC106523044 isoform X1.	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	0.591
LOC106523044	LOC106525162	A0A2I4BVK5	A0A2I4C440	Uncharacterized protein LOC106523044 isoform X1.	Extracellular serine/threonine protein kinase FAM20C-like.	0.582
LOC106523044	LOC106529655	A0A2I4BVK5	A0A2I4CKS2	Uncharacterized protein LOC106523044 isoform X1.	Transforming growth factor beta-1-like.	0.458
LOC106525162	LOC106523044	A0A2I4C440	A0A2I4BVK5	Extracellular serine/threonine protein kinase FAM20C-like.	Uncharacterized protein LOC106523044 isoform X1.	0.582
LOC106529655	LOC106523044	A0A2I4CKS2	A0A2I4BVK5	Transforming growth factor beta-1-like.	Uncharacterized protein LOC106523044 isoform X1.	0.458
LOC106533687	LOC106535376	A0A2I4CZZ6	A0A2I4D6H0	V-type proton ATPase subunit S1-like.	V-type proton ATPase subunit S1-like.	0.902
LOC106535376	LOC106533687	A0A2I4D6H0	A0A2I4CZZ6	V-type proton ATPase subunit S1-like.	V-type proton ATPase subunit S1-like.	0.902
dcstamp	LOC106511186	A0A2I4BXX7	A0A2I4AIS2	Dendritic cell-specific transmembrane protein isoform X1.	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	0.561
dcstamp	ocstamp	A0A2I4BXX7	A0A2I4BV96	Dendritic cell-specific transmembrane protein isoform X1.	Osteoclast stimulatory transmembrane protein.	0.603
ocstamp	dcstamp	A0A2I4BV96	A0A2I4BXX7	Osteoclast stimulatory transmembrane protein.	Dendritic cell-specific transmembrane protein isoform X1.	0.603
ostm1	LOC106511186	A0A2I4BCJ2	A0A2I4AIS2	Osteopetrosis-associated transmembrane protein 1.	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	0.407
ostm1	tnfrsf11a	A0A2I4BCJ2	A0A2I4B840	Osteopetrosis-associated transmembrane protein 1.	Tumor necrosis factor receptor superfamily member 11A.	0.408
src	LOC106512030	A0A2I4CZY8	A0A2I4AKZ9	Tyrosine-protein kinase.	Proto-oncogene tyrosine-protein kinase Src-like.	0.901
tnfrsf11a	LOC106511186	A0A2I4B840	A0A2I4AIS2	Tumor necrosis factor receptor superfamily member 11A.	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	0.998
tnfrsf11a	ostm1	A0A2I4B840	A0A2I4BCJ2	Tumor necrosis factor receptor superfamily member 11A.	Osteopetrosis-associated transmembrane protein 1.	0.408