STRINGSTRING
itfg2 itfg2 nprl3 nprl3 kptn kptn sh3bp4 sh3bp4 LOC106530689 LOC106530689 fnip1 fnip1 rnf152 rnf152 LOC106524812 LOC106524812 sirt1 sirt1 stk11 stk11 LOC106527806 LOC106527806 deptor deptor LOC106511172 LOC106511172 LOC106537106 LOC106537106 LOC106536558 LOC106536558 LOC106535658 LOC106535658 LOC106535279 LOC106535279 mapkapk5 mapkapk5 LOC106533160 LOC106533160 LOC106532744 LOC106532744 tsc2 tsc2 LOC106532331 LOC106532331 tbc1d7 tbc1d7 flcn flcn atm atm ubr1 ubr1 kiaa1024 kiaa1024 gsk3b gsk3b tmem127 tmem127 LOC106519557 LOC106519557 LOC106519447 LOC106519447 sesn1 sesn1 depdc5 depdc5 szt2 szt2 LOC106517283 LOC106517283 LOC106517282 LOC106517282 ddit4 ddit4 prkaa1 prkaa1 nprl2 nprl2 LOC106515752 LOC106515752 LOC106515654 LOC106515654 gatsl2 gatsl2 tsc1 tsc1 LOC106522150 LOC106522150
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
itfg2Integrin-alpha FG-GAP repeat-containing protein 2. (431 aa)
nprl3Nitrogen permease regulator 3-like protein isoform X1. (609 aa)
kptnKaptin. (433 aa)
sh3bp4SH3 domain-binding protein 4. (962 aa)
LOC106530689Non-specific serine/threonine protein kinase. (557 aa)
fnip1Folliculin-interacting protein 1 isoform X1. (1274 aa)
rnf152E3 ubiquitin-protein ligase RNF152 isoform X1. (216 aa)
LOC106524812Uncharacterized protein LOC106524812. (353 aa)
sirt1NAD-dependent protein deacetylase sirtuin-1. (690 aa)
stk11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (438 aa)
LOC106527806Hamartin-like isoform X1. (1014 aa)
deptorDEP domain-containing mTOR-interacting protein. (404 aa)
LOC106511172Glycogen synthase kinase-3 beta-like. (128 aa)
LOC106537106E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1566 aa)
LOC106536558E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (997 aa)
LOC106535658E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (273 aa)
LOC106535279Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (421 aa)
mapkapk5MAP kinase-activated protein kinase 5. (470 aa)
LOC106533160E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (568 aa)
LOC106532744UPF0536 protein C12orf66 homolog. (452 aa)
tsc2Tuberin. (1863 aa)
LOC106532331Glycogen synthase kinase-3 alpha-like; Belongs to the protein kinase superfamily. (440 aa)
tbc1d7TBC1 domain family member 7. (294 aa)
flcnFolliculin. (552 aa)
atmNon-specific serine/threonine protein kinase. (3066 aa)
ubr1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1740 aa)
kiaa1024UPF0258 protein KIAA1024 homolog. (871 aa)
gsk3bGlycogen synthase kinase-3 beta. (138 aa)
tmem127Transmembrane protein 127. (237 aa)
LOC106519557Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily. (438 aa)
LOC106519447GATS-like protein 3. (350 aa)
sesn1Sestrin-1-like. (545 aa)
depdc5DEP domain-containing protein 5. (1561 aa)
szt2Protein SZT2. (3672 aa)
LOC106517283S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (392 aa)
LOC106517282Uncharacterized protein LOC106517282. (1109 aa)
ddit4DNA damage-inducible transcript 4 protein. (226 aa)
prkaa1Non-specific serine/threonine protein kinase. (573 aa)
nprl2Nitrogen permease regulator 2-like protein isoform X1. (414 aa)
LOC106515752Sestrin-2-like isoform X1. (568 aa)
LOC106515654Sestrin-3-like. (444 aa)
gatsl2GATS-like protein 2 isoform X1. (343 aa)
tsc1Hamartin. (1270 aa)
LOC106522150Serine-protein kinase ATM-like; Belongs to the PI3/PI4-kinase family. (391 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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