(59 nodes) Regulation of peptidyl-serine phosphorylation network (Austrofundulus limnaeus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106535558	Interferon a3-like. (185 aa)
	LOC106535680	Teneurin-1-like. (849 aa)
	LOC106512599	Laforin-like. (255 aa)
	nck1	Cytoplasmic protein. (393 aa)
	dkk1	Dickkopf-related protein 1. (252 aa)
	LOC106513520	Progestin and adipoQ receptor family member 3-like isoform X1. (331 aa)
	oxt	Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. (154 aa)
	gas6	Growth arrest-specific protein 6. (651 aa)
	LOC106514100	Inositol polyphosphate 5-phosphatase K-like isoform X1. (531 aa)
	inpp5j	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A. (760 aa)
	LOC106514552	SH2 domain-containing protein 3C-like. (922 aa)
	rictor	Rapamycin-insensitive companion of mTOR isoform X1. (1436 aa)
	LOC106516714	Rapamycin-insensitive companion of mTOR-like. (274 aa)
	bag4	BAG family molecular chaperone regulator 4. (377 aa)
	ptgs2	Prostaglandin G/H synthase 2. (608 aa)
	LOC106517262	Secreted frizzled-related protein 2-like. (343 aa)
	LOC106517727	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific-like isoform X1. (2097 aa)
	LOC106517961	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (183 aa)
	LOC106518866	Protein sprouty homolog 2-like. (336 aa)
	mad2l2	Mitotic spindle assembly checkpoint protein MAD2B. (210 aa)
	LOC106519619	Breast cancer anti-estrogen resistance protein 3-like. (671 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	epm2a	Laforin. (316 aa)
	nck2	Cytoplasmic protein. (396 aa)
	vegfa	Vascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (227 aa)
	LOC106520498	Uncharacterized protein LOC106520498. (209 aa)
	LOC106521356	Sarcoplasmic reticulum histidine-rich calcium-binding protein-like. (260 aa)
	pwp1	Periodic tryptophan protein 1 homolog. (491 aa)
	paqr3	Progestin and adipoQ receptor family member 3. (341 aa)
	sh2d3c	SH2 domain-containing protein 3C isoform X1. (842 aa)
	mapkap1	Target of rapamycin complex 2 subunit MAPKAP1. (544 aa)
	LOC106522807	Protein phosphatase 1 regulatory subunit 15A-like. (562 aa)
	LOC106522985	Rap guanine nucleotide exchange factor 3-like isoform X1. (867 aa)
	smyd3	Histone-lysine N-methyltransferase SMYD3. (444 aa)
	LOC106523781	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like isoform X1. (693 aa)
	LOC106524130	Nerve growth factor-like; Belongs to the NGF-beta family. (281 aa)
	ercc6	DNA excision repair protein ERCC-6. (1438 aa)
	ntf3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (304 aa)
	LOC106524804	Uncharacterized protein LOC106524804; Belongs to the NGF-beta family. (438 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1108 aa)
	LOC106526341	B2 bradykinin receptor-like; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	LOC106526563	Apoptosis regulator BAX-like isoform X1. (203 aa)
	LOC106526906	LOW QUALITY PROTEIN: regulatory-associated protein of mTOR-like. (1464 aa)
	LOC106535805	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (222 aa)
	LOC106527240	Teneurin-1-like. (2231 aa)
	hax1	HCLS1-associated protein X-1. (301 aa)
	LOC106528493	Inositol polyphosphate 5-phosphatase K-like isoform X2. (490 aa)
	pink1	Serine/threonine-protein kinase PINK1, mitochondrial. (586 aa)
	stox1	Storkhead-box protein 1. (1082 aa)
	LOC106529655	Transforming growth factor beta-1-like. (474 aa)
	LOC106529768	Receptor activity-modifying protein 3-like isoform X1. (165 aa)
	ripk2	Receptor-interacting serine/threonine-protein kinase 2 isoform X1. (577 aa)
	ucn	Urocortin. (138 aa)
	fnip1	Folliculin-interacting protein 1 isoform X1. (1274 aa)
	LOC106531274	Breast cancer anti-estrogen resistance protein 3-like. (1101 aa)
	LOC106532900	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific-like. (2473 aa)
	bcl2	Apoptosis regulator Bcl-2 isoform X1. (279 aa)
	LOC106535210	Vascular endothelial growth factor A-like; Belongs to the PDGF/VEGF growth factor family. (145 aa)
	LOC106535265	Regulatory-associated protein of mTOR-like. (387 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106514100	LOC106523781	A0A2I4AT22	A0A2I4BYF0	Inositol polyphosphate 5-phosphatase K-like isoform X1.	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like isoform X1.	0.901
LOC106514100	LOC106528493	A0A2I4AT22	A0A2I4CGL2	Inositol polyphosphate 5-phosphatase K-like isoform X1.	Inositol polyphosphate 5-phosphatase K-like isoform X2.	0.901
LOC106516714	LOC106526906	A0A2I4B4L3	A0A2I4CAR5	Rapamycin-insensitive companion of mTOR-like.	LOW QUALITY PROTEIN: regulatory-associated protein of mTOR-like.	0.703
LOC106516714	LOC106535265	A0A2I4B4L3	A0A2I4D613	Rapamycin-insensitive companion of mTOR-like.	Regulatory-associated protein of mTOR-like.	0.703
LOC106516714	mapkap1	A0A2I4B4L3	A0A2I4BS59	Rapamycin-insensitive companion of mTOR-like.	Target of rapamycin complex 2 subunit MAPKAP1.	0.984
LOC106516714	rictor	A0A2I4B4L3	A0A2I4B4J3	Rapamycin-insensitive companion of mTOR-like.	Rapamycin-insensitive companion of mTOR isoform X1.	0.951
LOC106517262	dkk1	A0A2I4B6U4	A0A2I4AQS6	Secreted frizzled-related protein 2-like.	Dickkopf-related protein 1.	0.450
LOC106523781	LOC106514100	A0A2I4BYF0	A0A2I4AT22	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like isoform X1.	Inositol polyphosphate 5-phosphatase K-like isoform X1.	0.901
LOC106523781	LOC106528493	A0A2I4BYF0	A0A2I4CGL2	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like isoform X1.	Inositol polyphosphate 5-phosphatase K-like isoform X2.	0.900
LOC106524130	LOC106529655	A0A2I4BZU2	A0A2I4CKS2	Nerve growth factor-like; Belongs to the NGF-beta family.	Transforming growth factor beta-1-like.	0.410
LOC106524130	ret	A0A2I4BZU2	A0A2I4C5X4	Nerve growth factor-like; Belongs to the NGF-beta family.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.491
LOC106524130	ripk2	A0A2I4BZU2	A0A2I4CMK9	Nerve growth factor-like; Belongs to the NGF-beta family.	Receptor-interacting serine/threonine-protein kinase 2 isoform X1.	0.533
LOC106526563	bcl2	A0A2I4C9J6	A0A2I4D235	Apoptosis regulator BAX-like isoform X1.	Apoptosis regulator Bcl-2 isoform X1.	0.982
LOC106526906	LOC106516714	A0A2I4CAR5	A0A2I4B4L3	LOW QUALITY PROTEIN: regulatory-associated protein of mTOR-like.	Rapamycin-insensitive companion of mTOR-like.	0.703
LOC106526906	mapkap1	A0A2I4CAR5	A0A2I4BS59	LOW QUALITY PROTEIN: regulatory-associated protein of mTOR-like.	Target of rapamycin complex 2 subunit MAPKAP1.	0.714
LOC106526906	rictor	A0A2I4CAR5	A0A2I4B4J3	LOW QUALITY PROTEIN: regulatory-associated protein of mTOR-like.	Rapamycin-insensitive companion of mTOR isoform X1.	0.703
LOC106528493	LOC106514100	A0A2I4CGL2	A0A2I4AT22	Inositol polyphosphate 5-phosphatase K-like isoform X2.	Inositol polyphosphate 5-phosphatase K-like isoform X1.	0.901
LOC106528493	LOC106523781	A0A2I4CGL2	A0A2I4BYF0	Inositol polyphosphate 5-phosphatase K-like isoform X2.	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like isoform X1.	0.900
LOC106529655	LOC106524130	A0A2I4CKS2	A0A2I4BZU2	Transforming growth factor beta-1-like.	Nerve growth factor-like; Belongs to the NGF-beta family.	0.410
LOC106529655	bcl2	A0A2I4CKS2	A0A2I4D235	Transforming growth factor beta-1-like.	Apoptosis regulator Bcl-2 isoform X1.	0.404