(14 nodes) Protein-lipid complex remodeling network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106521567	Lipoprotein lipase-like isoform X1. (511 aa)
	pltp	Phospholipid transfer protein. (486 aa)
	apoe	Apolipoprotein E. (251 aa)
	LOC106528583	Phospholipase A(2). (152 aa)
	LOC106523750	Apolipoprotein Eb-like. (265 aa)
	apob	Apolipoprotein B-100 isoform X1. (3804 aa)
	cetp	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (499 aa)
	LOC106534304	Apolipoprotein B-100-like. (3309 aa)
	LOC106512370	Cholesteryl ester transfer protein-like. (163 aa)
	apom	Apolipoprotein M isoform X1. (191 aa)
	lcat	Phosphatidylcholine-sterol acyltransferase. (445 aa)
	LOC106521237	Apolipoprotein B-100-like isoform X1. (4384 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (516 aa)
	scarb1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (521 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106512370	LOC106521237	A0A2I4ALT6	A0A2I4BN50	Cholesteryl ester transfer protein-like.	Apolipoprotein B-100-like isoform X1.	0.601
LOC106512370	LOC106523750	A0A2I4ALT6	A0A2I4BYB0	Cholesteryl ester transfer protein-like.	Apolipoprotein Eb-like.	0.440
LOC106512370	LOC106534304	A0A2I4ALT6	A0A2I4D288	Cholesteryl ester transfer protein-like.	Apolipoprotein B-100-like.	0.601
LOC106512370	apob	A0A2I4ALT6	A0A2I4BTW0	Cholesteryl ester transfer protein-like.	Apolipoprotein B-100 isoform X1.	0.601
LOC106512370	lcat	A0A2I4ALT6	A0A2I4BIU4	Cholesteryl ester transfer protein-like.	Phosphatidylcholine-sterol acyltransferase.	0.523
LOC106512370	lpl	A0A2I4ALT6	A0A2I4BPH7	Cholesteryl ester transfer protein-like.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.426
LOC106521237	LOC106512370	A0A2I4BN50	A0A2I4ALT6	Apolipoprotein B-100-like isoform X1.	Cholesteryl ester transfer protein-like.	0.601
LOC106521237	LOC106523750	A0A2I4BN50	A0A2I4BYB0	Apolipoprotein B-100-like isoform X1.	Apolipoprotein Eb-like.	0.780
LOC106521237	apoe	A0A2I4BN50	A0A2I4CMA5	Apolipoprotein B-100-like isoform X1.	Apolipoprotein E.	0.702
LOC106521237	cetp	A0A2I4BN50	A0A2I4D8T7	Apolipoprotein B-100-like isoform X1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.601
LOC106521237	lcat	A0A2I4BN50	A0A2I4BIU4	Apolipoprotein B-100-like isoform X1.	Phosphatidylcholine-sterol acyltransferase.	0.438
LOC106521237	pltp	A0A2I4BN50	A0A2I4BNN2	Apolipoprotein B-100-like isoform X1.	Phospholipid transfer protein.	0.515
LOC106521237	scarb1	A0A2I4BN50	A0A2I4CUA7	Apolipoprotein B-100-like isoform X1.	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family.	0.736
LOC106521567	lpl	A0A2I4BPK8	A0A2I4BPH7	Lipoprotein lipase-like isoform X1.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.903
LOC106523750	LOC106512370	A0A2I4BYB0	A0A2I4ALT6	Apolipoprotein Eb-like.	Cholesteryl ester transfer protein-like.	0.440
LOC106523750	LOC106521237	A0A2I4BYB0	A0A2I4BN50	Apolipoprotein Eb-like.	Apolipoprotein B-100-like isoform X1.	0.780
LOC106523750	LOC106534304	A0A2I4BYB0	A0A2I4D288	Apolipoprotein Eb-like.	Apolipoprotein B-100-like.	0.780
LOC106523750	apob	A0A2I4BYB0	A0A2I4BTW0	Apolipoprotein Eb-like.	Apolipoprotein B-100 isoform X1.	0.780
LOC106523750	cetp	A0A2I4BYB0	A0A2I4D8T7	Apolipoprotein Eb-like.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.440
LOC106523750	lcat	A0A2I4BYB0	A0A2I4BIU4	Apolipoprotein Eb-like.	Phosphatidylcholine-sterol acyltransferase.	0.467