(26 nodes) Cellular response to heat network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mki67	Antigen KI-67 isoform X1. (1845 aa)
	LOC106516822	Nucleoprotein TPR-like. (369 aa)
	tpr	Nucleoprotein TPR. (1975 aa)
	LOC106516686	Immediate early response gene 5-like protein. (286 aa)
	LOC106514623	14-3-3 protein epsilon; Belongs to the 14-3-3 family. (257 aa)
	hsbp1	Heat shock factor-binding protein 1. (77 aa)
	LOC106534650	Neurofibromin. (2131 aa)
	LOC106534272	Protein Hikeshi. (220 aa)
	st8sia1	alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Belongs to the glycosyltransferase 29 family. (335 aa)
	LOC106533044	Heat shock protein HSP 90-alpha 1. (724 aa)
	LOC106533043	LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like. (733 aa)
	ier5l	Immediate early response gene 5-like protein. (260 aa)
	LOC106532737	14-3-3 protein epsilon-like; Belongs to the 14-3-3 family. (255 aa)
	LOC106532634	DNA-directed RNA polymerase II subunit RPB4. (143 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	nf1	Neurofibromin isoform X1. (2016 aa)
	LOC106525615	BAG family molecular chaperone regulator 3-like. (487 aa)
	LOC106524922	Nucleoprotein TPR-like isoform X1. (2502 aa)
	tfec	Transcription factor EC isoform X1. (429 aa)
	hsp90ab1	Heat shock protein HSP 90-beta. (724 aa)
	LOC106521902	Uncharacterized protein C8orf4 homolog. (100 aa)
	daxx	Death domain-associated protein 6. (746 aa)
	dhx36	ATP-dependent RNA helicase DHX36. (1071 aa)
	LOC106512772	DNA-directed RNA polymerase II subunit RPB4-like. (139 aa)
	LOC106511993	Nucleoprotein TPR-like isoform X1. (313 aa)
	clpb	Caseinolytic peptidase B protein homolog. (676 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511993	LOC106516822	A0A2I4AKW9	A0A2I4B513	Nucleoprotein TPR-like isoform X1.	Nucleoprotein TPR-like.	0.854
LOC106511993	sumo1	A0A2I4AKW9	A0A2I4CS05	Nucleoprotein TPR-like isoform X1.	Small ubiquitin-related modifier.	0.427
LOC106512772	LOC106532634	A0A2I4AMM8	A0A2I4CW42	DNA-directed RNA polymerase II subunit RPB4-like.	DNA-directed RNA polymerase II subunit RPB4.	0.900
LOC106514623	LOC106525615	A0A2I4AVC7	A0A2I4C5T1	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	BAG family molecular chaperone regulator 3-like.	0.414
LOC106514623	LOC106532737	A0A2I4AVC7	A0A2I4CWG6	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	14-3-3 protein epsilon-like; Belongs to the 14-3-3 family.	0.900
LOC106514623	LOC106533043	A0A2I4AVC7	A0A2I4CXH8	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like.	0.556
LOC106514623	LOC106533044	A0A2I4AVC7	A0A2I4CXJ1	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	Heat shock protein HSP 90-alpha 1.	0.556
LOC106514623	hsp90ab1	A0A2I4AVC7	A0A2I4BT45	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	Heat shock protein HSP 90-beta.	0.556
LOC106516822	LOC106511993	A0A2I4B513	A0A2I4AKW9	Nucleoprotein TPR-like.	Nucleoprotein TPR-like isoform X1.	0.854
LOC106516822	sumo1	A0A2I4B513	A0A2I4CS05	Nucleoprotein TPR-like.	Small ubiquitin-related modifier.	0.427
LOC106516822	tpr	A0A2I4B513	A0A2I4B4Y8	Nucleoprotein TPR-like.	Nucleoprotein TPR.	0.913
LOC106524922	sumo1	A0A2I4C344	A0A2I4CS05	Nucleoprotein TPR-like isoform X1.	Small ubiquitin-related modifier.	0.427
LOC106524922	tpr	A0A2I4C344	A0A2I4B4Y8	Nucleoprotein TPR-like isoform X1.	Nucleoprotein TPR.	0.905
LOC106525615	LOC106514623	A0A2I4C5T1	A0A2I4AVC7	BAG family molecular chaperone regulator 3-like.	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	0.414
LOC106525615	LOC106532737	A0A2I4C5T1	A0A2I4CWG6	BAG family molecular chaperone regulator 3-like.	14-3-3 protein epsilon-like; Belongs to the 14-3-3 family.	0.414
LOC106532634	LOC106512772	A0A2I4CW42	A0A2I4AMM8	DNA-directed RNA polymerase II subunit RPB4.	DNA-directed RNA polymerase II subunit RPB4-like.	0.900
LOC106532737	LOC106514623	A0A2I4CWG6	A0A2I4AVC7	14-3-3 protein epsilon-like; Belongs to the 14-3-3 family.	14-3-3 protein epsilon; Belongs to the 14-3-3 family.	0.900
LOC106532737	LOC106525615	A0A2I4CWG6	A0A2I4C5T1	14-3-3 protein epsilon-like; Belongs to the 14-3-3 family.	BAG family molecular chaperone regulator 3-like.	0.414
LOC106532737	LOC106533043	A0A2I4CWG6	A0A2I4CXH8	14-3-3 protein epsilon-like; Belongs to the 14-3-3 family.	LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like.	0.556
LOC106532737	LOC106533044	A0A2I4CWG6	A0A2I4CXJ1	14-3-3 protein epsilon-like; Belongs to the 14-3-3 family.	Heat shock protein HSP 90-alpha 1.	0.556