STRINGSTRING
phykpl phykpl LOC106535094 LOC106535094 LOC106535057 LOC106535057 prkcb prkcb LOC106534203 LOC106534203 sh2b3 sh2b3 LOC106532785 LOC106532785 tbx20 tbx20 LOC106531382 LOC106531382 LOC106531136 LOC106531136 gja1 gja1 slc40a1 slc40a1 LOC106511129 LOC106511129 LOC106512523 LOC106512523 etnppl etnppl rps24 rps24 ism1 ism1 LOC106516520 LOC106516520 med1 med1 hdac9 hdac9 lclat1 lclat1 LOC106518604 LOC106518604 LOC106518739 LOC106518739 cftr cftr LOC106518915 LOC106518915 LOC106519273 LOC106519273 LOC106519663 LOC106519663 slc25a37 slc25a37 LOC106520517 LOC106520517 yap1 yap1 ccdc134 ccdc134 LOC106520852 LOC106520852 atf4 atf4 LOC106523249 LOC106523249 LOC106524166 LOC106524166 LOC106524540 LOC106524540 LOC106525496 LOC106525496 tll1 tll1 lmo2 lmo2 nop10 nop10 ncoa2 ncoa2 chrd chrd bmi1 bmi1 trim33 trim33
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phykpl5-phosphohydroxy-L-lysine phospho-lyase isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
LOC106535094Nuclear receptor coactivator. (1514 aa)
LOC106535057T-cell acute lymphocytic leukemia protein 1. (234 aa)
prkcbProtein kinase C beta type isoform X1. (550 aa)
LOC106534203Metalloendopeptidase. (968 aa)
sh2b3SH2B adapter protein 3 isoform X1. (720 aa)
LOC106532785Erythroid transcription factor-like. (247 aa)
tbx20T-box transcription factor TBX20. (440 aa)
LOC106531382GATA-binding factor 2-like. (430 aa)
LOC106531136T-cell acute lymphocytic leukemia protein 2-like. (172 aa)
gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (388 aa)
slc40a1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (567 aa)
LOC106511129Hematopoietically-expressed homeobox protein hhex-like. (271 aa)
LOC106512523T-cell acute lymphocytic leukemia protein 1-like. (239 aa)
etnpplEthanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (489 aa)
rps2440S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (132 aa)
ism1Isthmin-1. (447 aa)
LOC106516520Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1785 aa)
hdac9LOW QUALITY PROTEIN: histone deacetylase 9. (617 aa)
lclat1Lysocardiolipin acyltransferase 1 isoform X1. (414 aa)
LOC106518604Myc target protein 1 homolog. (202 aa)
LOC106518739Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (709 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1503 aa)
LOC106518915E3 ubiquitin-protein ligase TRIM33-like. (356 aa)
LOC106519273TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa)
LOC106519663Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
slc25a37Mitoferrin-1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (337 aa)
LOC106520517Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
yap1Transcriptional coactivator YAP1. (438 aa)
ccdc134Coiled-coil domain-containing protein 134. (229 aa)
LOC106520852TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)
atf4Cyclic AMP-dependent transcription factor ATF-4. (443 aa)
LOC106523249Non-specific serine/threonine protein kinase. (319 aa)
LOC1065241665-aminolevulinate synthase. (591 aa)
LOC106524540Protein kinase C alpha type-like. (150 aa)
LOC106525496TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
tll1Metalloendopeptidase. (1024 aa)
lmo2Rhombotin-2. (160 aa)
nop10H/ACA ribonucleoprotein complex subunit 3. (64 aa)
ncoa2Nuclear receptor coactivator. (1505 aa)
chrdChordin; Belongs to the chordin family. (974 aa)
bmi1Polycomb complex protein BMI-1. (336 aa)
trim33E3 ubiquitin-protein ligase TRIM33 isoform X1. (1190 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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