(26 nodes) Non-canonical Wnt signaling pathway network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ift80	Intraflagellar transport protein 80 homolog isoform X1. (796 aa)
	adgra3	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1343 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
	LOC106517262	Secreted frizzled-related protein 2-like. (343 aa)
	LOC106519008	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
	vangl1	Vang-like protein. (527 aa)
	dvl1	Segment polarity protein dishevelled homolog DVL-1 isoform X1. (720 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC106519701	frizzled-7-A-like; Belongs to the G-protein coupled receptor Fz/Smo family. (561 aa)
	vangl2	Vang-like protein. (525 aa)
	fzd4	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
	LOC106521788	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
	ptk7	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1067 aa)
	LOC106523711	Vang-like protein. (526 aa)
	LOC106523963	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	LOC106526881	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	fzd2	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (542 aa)
	LOC106528191	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	LOC106529207	Uncharacterized protein LOC106529207. (898 aa)
	dvl2	Segment polarity protein dishevelled homolog DVL-2. (761 aa)
	LOC106532337	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	dvl3	LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-3. (653 aa)
	ryk	Tyrosine-protein kinase RYK isoform X1. (627 aa)
	LOC106535975	Segment polarity protein dishevelled homolog DVL-3-like. (684 aa)
	LOC106537356	Segment polarity protein dishevelled homolog DVL-2-like. (661 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106517262	LOC106519008	A0A2I4B6U4	A0A2I4BDV8	Secreted frizzled-related protein 2-like.	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.689
LOC106517262	LOC106519701	A0A2I4B6U4	A0A2I4BGT5	Secreted frizzled-related protein 2-like.	frizzled-7-A-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.688
LOC106517262	LOC106521788	A0A2I4B6U4	A0A2I4BQF9	Secreted frizzled-related protein 2-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.831
LOC106517262	LOC106523711	A0A2I4B6U4	A0A2I4BY63	Secreted frizzled-related protein 2-like.	Vang-like protein.	0.407
LOC106517262	LOC106523963	A0A2I4B6U4	A0A2I4BZ43	Secreted frizzled-related protein 2-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.831
LOC106517262	LOC106526881	A0A2I4B6U4	A0A2I4CAN3	Secreted frizzled-related protein 2-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.803
LOC106517262	LOC106528191	A0A2I4B6U4	A0A2I4CFI7	Secreted frizzled-related protein 2-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.803
LOC106517262	LOC106532337	A0A2I4B6U4	A0A2I4CV09	Secreted frizzled-related protein 2-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.803
LOC106517262	LOC106535975	A0A2I4B6U4	A0A2I4D8L2	Secreted frizzled-related protein 2-like.	Segment polarity protein dishevelled homolog DVL-3-like.	0.468
LOC106517262	LOC106537356	A0A2I4B6U4	A0A2I4DD75	Secreted frizzled-related protein 2-like.	Segment polarity protein dishevelled homolog DVL-2-like.	0.468
LOC106517262	dvl1	A0A2I4B6U4	A0A2I4BF72	Secreted frizzled-related protein 2-like.	Segment polarity protein dishevelled homolog DVL-1 isoform X1.	0.468
LOC106517262	dvl2	A0A2I4B6U4	A0A2I4CJ53	Secreted frizzled-related protein 2-like.	Segment polarity protein dishevelled homolog DVL-2.	0.468
LOC106517262	dvl3	A0A2I4B6U4	A0A2I4CW57	Secreted frizzled-related protein 2-like.	LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-3.	0.468
LOC106517262	fzd2	A0A2I4B6U4	A0A2I4CFH6	Secreted frizzled-related protein 2-like.	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.688
LOC106517262	fzd4	A0A2I4B6U4	A0A2I4BP43	Secreted frizzled-related protein 2-like.	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.650
LOC106517262	vangl1	A0A2I4B6U4	A0A2I4BEM2	Secreted frizzled-related protein 2-like.	Vang-like protein.	0.407
LOC106517262	vangl2	A0A2I4B6U4	A0A2I4BL52	Secreted frizzled-related protein 2-like.	Vang-like protein.	0.438
LOC106517262	wnt11	A0A2I4B6U4	A0A2I4B6L6	Secreted frizzled-related protein 2-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.819
LOC106517262	wnt7b	A0A2I4B6U4	A0A2I4BQI9	Secreted frizzled-related protein 2-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.803
LOC106519008	LOC106517262	A0A2I4BDV8	A0A2I4B6U4	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.689