STRINGSTRING
tpi1 tpi1 LOC106537117 LOC106537117 LOC106537020 LOC106537020 aifm2 aifm2 LOC106536512 LOC106536512 LOC106536452 LOC106536452 tdo2 tdo2 coq9 coq9 LOC106536168 LOC106536168 LOC106535596 LOC106535596 LOC106535286 LOC106535286 pddc1 pddc1 kdsr kdsr LOC106533352 LOC106533352 LOC106533004 LOC106533004 srd5a1 srd5a1 LOC106532554 LOC106532554 LOC106532507 LOC106532507 LOC106532442 LOC106532442 LOC106532441 LOC106532441 LOC106532287 LOC106532287 got2 got2 LOC106532172 LOC106532172 hagh hagh LOC106531248 LOC106531248 coq10b coq10b LOC106530762 LOC106530762 aadat aadat LOC106530016 LOC106530016 coq2 coq2 glod4 glod4 coq3 coq3 cbr1 cbr1 cryzl1 cryzl1 LOC106527183 LOC106527183 kmo kmo LOC106526537 LOC106526537 sirt6 sirt6 LOC106525764 LOC106525764 LOC106525458 LOC106525458 LOC106525457 LOC106525457 vkorc1 vkorc1 LOC106525137 LOC106525137 LOC106525136 LOC106525136 aldh8a1 aldh8a1 LOC106524760 LOC106524760 coq7 coq7 glo1 glo1 LOC106523281 LOC106523281 LOC106522973 LOC106522973 coq4 coq4 LOC106522119 LOC106522119 afmid afmid LOC106521363 LOC106521363 coq6 coq6 LOC106520011 LOC106520011 LOC106519593 LOC106519593 coq5 coq5 ubiad1 ubiad1 pdss2 pdss2 pnkd pnkd ccbl1 ccbl1 srd5a2 srd5a2 pdss1 pdss1 LOC106515325 LOC106515325 LOC106514977 LOC106514977 park7 park7 LOC106513815 LOC106513815 hsd17b3 hsd17b3 hsd17b10 hsd17b10 LOC106511002 LOC106511002 LOC106510917 LOC106510917
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tpi1Triosephosphate isomerase. (247 aa)
LOC106537117NAD(P)H dehydrogenase [quinone] 1-like. (284 aa)
LOC106537020NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial-like. (380 aa)
aifm2Apoptosis-inducing factor 2. (372 aa)
LOC106536512Coenzyme Q-binding protein COQ10 homolog B, mitochondrial-like. (238 aa)
LOC106536452Kynurenine--oxoglutarate transaminase 3-like. (310 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (405 aa)
coq9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (330 aa)
LOC106536168Atypical kinase ADCK3, mitochondrial-like. (591 aa)
LOC106535596aarF domain-containing protein kinase 4-like. (645 aa)
LOC106535286Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (468 aa)
pddc1Parkinson disease 7 domain-containing protein 1. (213 aa)
kdsr3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (359 aa)
LOC106533352Kynureninase-like. (173 aa)
LOC1065330043-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (252 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (265 aa)
LOC106532554Indoleamine 2,3-dioxygenase 2-like. (420 aa)
LOC106532507Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (649 aa)
LOC106532442NAD(P)H dehydrogenase [quinone] 1-like. (199 aa)
LOC106532441Ribosyldihydronicotinamide dehydrogenase [quinone]-like isoform X1. (270 aa)
LOC106532287Ribosyldihydronicotinamide dehydrogenase [quinone]-like isoform X1. (277 aa)
got2Aspartate aminotransferase. (428 aa)
LOC106532172Corticosteroid 11-beta-dehydrogenase isozyme 2-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (412 aa)
haghHydroxyacylglutathione hydrolase, mitochondrial isoform X1. (309 aa)
LOC106531248LOW QUALITY PROTEIN: hydroxyacylglutathione hydrolase-like protein. (116 aa)
coq10bCoenzyme Q-binding protein COQ10 homolog B, mitochondrial. (107 aa)
LOC106530762Kynurenine--oxoglutarate transaminase 3-like. (449 aa)
aadatKynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. (425 aa)
LOC106530016Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (356 aa)
coq24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (351 aa)
glod4Glyoxalase domain-containing protein 4. (298 aa)
coq3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (331 aa)
cbr1Carbonyl reductase [NADPH] 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
cryzl1Quinone oxidoreductase-like protein 1. (347 aa)
LOC106527183Coenzyme Q-binding protein COQ10 homolog, mitochondrial-like. (246 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (473 aa)
LOC106526537Kynurenine 3-monooxygenase-like. (111 aa)
sirt6NAD-dependent protein deacetylase sirtuin-6. (349 aa)
LOC106525764Probable hydrolase PNKD. (359 aa)
LOC106525458Cholesterol 24-hydroxylase-like. (465 aa)
LOC106525457Cholesterol 24-hydroxylase-like isoform X1. (520 aa)
vkorc1Vitamin K epoxide reductase complex subunit 1. (176 aa)
LOC106525137Cholesterol 24-hydroxylase-like. (516 aa)
LOC106525136Cholesterol 24-hydroxylase-like; Belongs to the cytochrome P450 family. (175 aa)
aldh8a1Aldehyde dehydrogenase family 8 member A1; Belongs to the aldehyde dehydrogenase family. (490 aa)
LOC106524760Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (359 aa)
coq75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (271 aa)
glo1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
LOC106523281Kynurenine--oxoglutarate transaminase 3-like. (440 aa)
LOC106522973Coenzyme Q-binding protein COQ10 homolog A, mitochondrial-like. (249 aa)
coq4Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (272 aa)
LOC106522119aarF domain-containing protein kinase 4-like. (645 aa)
afmidKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (293 aa)
LOC106521363Vitamin K epoxide reductase complex subunit 1-like protein 1. (166 aa)
coq6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (481 aa)
LOC106520011Atypical kinase ADCK3, mitochondrial-like. (661 aa)
LOC106519593Triosephosphate isomerase. (248 aa)
coq52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (326 aa)
ubiad1ubiA prenyltransferase domain-containing protein 1. (358 aa)
pdss2Decaprenyl-diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (389 aa)
pnkdProbable hydrolase PNKD. (151 aa)
ccbl1Kynurenine--oxoglutarate transaminase 1. (446 aa)
srd5a23-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (253 aa)
pdss1Decaprenyl-diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (419 aa)
LOC106515325Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (515 aa)
LOC106514977Ribosyldihydronicotinamide dehydrogenase [quinone]-like isoform X1. (270 aa)
park7Protein deglycase DJ-1. (189 aa)
LOC106513815Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (419 aa)
hsd17b3Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
hsd17b103-hydroxyacyl-CoA dehydrogenase type-2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
LOC106511002Steroid 17-alpha-hydroxylase/17,20 lyase-like; Belongs to the cytochrome P450 family. (516 aa)
LOC106510917Steroid 17-alpha-hydroxylase/17,20 lyase-like. (188 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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