(13 nodes) Protein neddylation network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106535733	DCN1-like protein. (271 aa)
	LOC106536995	NEDD8. (89 aa)
	rbx1	E3 ubiquitin-protein ligase RBX1. (108 aa)
	rnf7	RING-box protein 2. (110 aa)
	ube2m	NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
	ube2f	NEDD8-conjugating enzyme UBE2F; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
	dcun1d4	DCN1-like protein. (280 aa)
	LOC106514957	NEDD8-like. (90 aa)
	nae1	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (533 aa)
	dcun1d2	DCN1-like protein. (247 aa)
	uba3	NEDD8-activating enzyme E1 catalytic subunit isoform X1. (446 aa)
	LOC106519301	NEDD8-activating enzyme E1 catalytic subunit. (460 aa)
	LOC106519817	DCN1-like protein. (293 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106514957	LOC106519301	A0A2I4AWV4	A0A2I4BF36	NEDD8-like.	NEDD8-activating enzyme E1 catalytic subunit.	0.897
LOC106514957	LOC106519817	A0A2I4AWV4	A0A2I4BH74	NEDD8-like.	DCN1-like protein.	0.838
LOC106514957	LOC106535733	A0A2I4AWV4	A0A2I4D7P0	NEDD8-like.	DCN1-like protein.	0.711
LOC106514957	dcun1d2	A0A2I4AWV4	A0A2I4ASP0	NEDD8-like.	DCN1-like protein.	0.838
LOC106514957	dcun1d4	A0A2I4AWV4	A0A2I4CSN3	NEDD8-like.	DCN1-like protein.	0.711
LOC106514957	nae1	A0A2I4AWV4	A0A2I4ASQ2	NEDD8-like.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.966
LOC106514957	rbx1	A0A2I4AWV4	A0A2I4BKS2	NEDD8-like.	E3 ubiquitin-protein ligase RBX1.	0.969
LOC106514957	rnf7	A0A2I4AWV4	A0A2I4C0X2	NEDD8-like.	RING-box protein 2.	0.926
LOC106514957	uba3	A0A2I4AWV4	A0A2I4BC28	NEDD8-like.	NEDD8-activating enzyme E1 catalytic subunit isoform X1.	0.897
LOC106514957	ube2f	A0A2I4AWV4	A0A2I4CJZ8	NEDD8-like.	NEDD8-conjugating enzyme UBE2F; Belongs to the ubiquitin-conjugating enzyme family.	0.884
LOC106514957	ube2m	A0A2I4AWV4	A0A2I4CF11	NEDD8-like.	NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.	0.884
LOC106519301	LOC106514957	A0A2I4BF36	A0A2I4AWV4	NEDD8-activating enzyme E1 catalytic subunit.	NEDD8-like.	0.897
LOC106519301	LOC106519817	A0A2I4BF36	A0A2I4BH74	NEDD8-activating enzyme E1 catalytic subunit.	DCN1-like protein.	0.698
LOC106519301	LOC106535733	A0A2I4BF36	A0A2I4D7P0	NEDD8-activating enzyme E1 catalytic subunit.	DCN1-like protein.	0.631
LOC106519301	LOC106536995	A0A2I4BF36	A0A2I4DC38	NEDD8-activating enzyme E1 catalytic subunit.	NEDD8.	0.897
LOC106519301	dcun1d2	A0A2I4BF36	A0A2I4ASP0	NEDD8-activating enzyme E1 catalytic subunit.	DCN1-like protein.	0.698
LOC106519301	dcun1d4	A0A2I4BF36	A0A2I4CSN3	NEDD8-activating enzyme E1 catalytic subunit.	DCN1-like protein.	0.631
LOC106519301	nae1	A0A2I4BF36	A0A2I4ASQ2	NEDD8-activating enzyme E1 catalytic subunit.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.988
LOC106519301	rbx1	A0A2I4BF36	A0A2I4BKS2	NEDD8-activating enzyme E1 catalytic subunit.	E3 ubiquitin-protein ligase RBX1.	0.814
LOC106519301	rnf7	A0A2I4BF36	A0A2I4C0X2	NEDD8-activating enzyme E1 catalytic subunit.	RING-box protein 2.	0.740