(27 nodes) Regulation of glial cell differentiation network (Austrofundulus limnaeus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	aspa	Aspartoacylase. (316 aa)
	nkx6-2	Homeobox protein Nkx-6.2. (280 aa)
	il6st	Interleukin-6 receptor subunit beta isoform X1. (875 aa)
	nkx6-1	Homeobox protein Nkx-6.1. (278 aa)
	LOC106513844	Tumor necrosis factor receptor superfamily member 5-like. (452 aa)
	LOC106517035	N-acyl-aromatic-L-amino acid amidohydrolase (Carboxylate-forming) B-like. (307 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
	spint1	Kunitz-type protease inhibitor 1. (478 aa)
	gsx2	GS homeobox 2. (237 aa)
	LOC106524586	Receptor-type tyrosine-protein phosphatase zeta-like. (1818 aa)
	LOC106524682	Nuclear receptor subfamily 1 group D member 1-like. (574 aa)
	LOC106525346	N-acyl-aromatic-L-amino acid amidohydrolase (Carboxylate-forming) B-like. (334 aa)
	nf1	Neurofibromin isoform X1. (2016 aa)
	tmem98	Transmembrane protein 98. (224 aa)
	LOC106528070	Nuclear receptor subfamily 1 group D member 1-like. (570 aa)
	LOC106528670	Kunitz-type protease inhibitor 1-like. (496 aa)
	LOC106529655	Transforming growth factor beta-1-like. (474 aa)
	cntn2	Contactin-2. (308 aa)
	ptprz1	Receptor-type tyrosine-protein phosphatase zeta isoform X1. (1532 aa)
	serpine2	Glia-derived nexin isoform X1; Belongs to the serpin family. (394 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (621 aa)
	LOC106531483	Zinc finger protein 252-like. (552 aa)
	tnfrsf21	Tumor necrosis factor receptor superfamily member 21. (676 aa)
	mib1	E3 ubiquitin-protein ligase MIB1 isoform X1. (1041 aa)
	LOC106534469	Contactin-2-like. (1039 aa)
	LOC106534650	Neurofibromin. (2131 aa)
	il34	Interleukin-34. (311 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106524586	LOC106534469	A0A2I4C1N2	A0A2I4D2U7	Receptor-type tyrosine-protein phosphatase zeta-like.	Contactin-2-like.	0.453
LOC106524586	cntn2	A0A2I4C1N2	A0A2I4CM77	Receptor-type tyrosine-protein phosphatase zeta-like.	Contactin-2.	0.453
LOC106524586	il34	A0A2I4C1N2	A0A2I4D9K0	Receptor-type tyrosine-protein phosphatase zeta-like.	Interleukin-34.	0.711
LOC106534469	LOC106524586	A0A2I4D2U7	A0A2I4C1N2	Contactin-2-like.	Receptor-type tyrosine-protein phosphatase zeta-like.	0.453
LOC106534469	ptprz1	A0A2I4D2U7	A0A2I4CMU2	Contactin-2-like.	Receptor-type tyrosine-protein phosphatase zeta isoform X1.	0.453
cntn2	LOC106524586	A0A2I4CM77	A0A2I4C1N2	Contactin-2.	Receptor-type tyrosine-protein phosphatase zeta-like.	0.453
cntn2	ptprz1	A0A2I4CM77	A0A2I4CMU2	Contactin-2.	Receptor-type tyrosine-protein phosphatase zeta isoform X1.	0.453
f2	serpine2	A0A2I4CRB0	A0A2I4CPH6	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Glia-derived nexin isoform X1; Belongs to the serpin family.	0.965
il34	LOC106524586	A0A2I4D9K0	A0A2I4C1N2	Interleukin-34.	Receptor-type tyrosine-protein phosphatase zeta-like.	0.711
il34	ptprz1	A0A2I4D9K0	A0A2I4CMU2	Interleukin-34.	Receptor-type tyrosine-protein phosphatase zeta isoform X1.	0.711
ptprz1	LOC106534469	A0A2I4CMU2	A0A2I4D2U7	Receptor-type tyrosine-protein phosphatase zeta isoform X1.	Contactin-2-like.	0.453
ptprz1	cntn2	A0A2I4CMU2	A0A2I4CM77	Receptor-type tyrosine-protein phosphatase zeta isoform X1.	Contactin-2.	0.453
ptprz1	il34	A0A2I4CMU2	A0A2I4D9K0	Receptor-type tyrosine-protein phosphatase zeta isoform X1.	Interleukin-34.	0.711
serpine2	f2	A0A2I4CPH6	A0A2I4CRB0	Glia-derived nexin isoform X1; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.965