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sptlc1 sptlc1 srd5a3 srd5a3 LOC106537088 LOC106537088 LOC106537015 LOC106537015 LOC106536933 LOC106536933 LOC106536934 LOC106536934 LOC106536770 LOC106536770 dhcr24 dhcr24 LOC106536159 LOC106536159 LOC106535662 LOC106535662 LOC106534563 LOC106534563 mvk mvk LOC106532953 LOC106532953 LOC106532599 LOC106532599 dhdds dhdds LOC106531768 LOC106531768 dhfr dhfr spr spr fdps fdps gba gba rusc1 rusc1 LOC106530854 LOC106530854 LOC106530689 LOC106530689 LOC106530620 LOC106530620 pck2 pck2 pts pts lss lss LOC106529311 LOC106529311 LOC106528429 LOC106528429 hsd17b7 hsd17b7 isyna1 isyna1 got1 got1 LOC106528220 LOC106528220 ppip5k1 ppip5k1 LOC106526640 LOC106526640 acer3 acer3 ptafr ptafr asah1 asah1 LOC106525612 LOC106525612 tmem130 tmem130 ip6k1 ip6k1 LOC106524717 LOC106524717 ebp ebp pck1 pck1 tm7sf2 tm7sf2 ippk ippk dhcr7 dhcr7 itpka itpka idi1 idi1 insig1 insig1 itpkb itpkb itpkc itpkc LOC106518993 LOC106518993 sphk1 sphk1 LOC106518494 LOC106518494 nus1 nus1 LOC106518131 LOC106518131 LOC106518084 LOC106518084 LOC106518001 LOC106518001 acer2 acer2 fdft1 fdft1 acer1 acer1 r3hdm4 r3hdm4 LOC106516620 LOC106516620 prkaa1 prkaa1 nsdhl nsdhl impa1 impa1 LOC106515519 LOC106515519 impad1 impad1 LOC106514613 LOC106514613 LOC106514612 LOC106514612 dbh dbh LOC106514257 LOC106514257 LOC106514037 LOC106514037 park7 park7 hmgcs1 hmgcs1 qdpr qdpr mvd mvd LOC106512276 LOC106512276 LOC106511262 LOC106511262 LOC106511198 LOC106511198
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sptlc1Serine palmitoyltransferase 1. (480 aa)
srd5a3Polyprenol reductase. (267 aa)
LOC106537088Kinase; Belongs to the inositol phosphokinase (IPK) family. (455 aa)
LOC106537015Sphingosine kinase 2-like. (896 aa)
LOC1065369333-hydroxy-3-methylglutaryl coenzyme A reductase. (868 aa)
LOC1065369343-hydroxy-3-methylglutaryl-coenzyme A reductase-like. (148 aa)
LOC106536770Kinase; Belongs to the inositol phosphokinase (IPK) family. (771 aa)
dhcr24Delta(24)-sterol reductase. (515 aa)
LOC106536159Sphingosine kinase 1-like. (562 aa)
LOC106535662Inositol-1-monophosphatase. (280 aa)
LOC106534563Sphingosine kinase 1-like. (489 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (399 aa)
LOC106532953lamin-B receptor-like. (545 aa)
LOC106532599Sterol 26-hydroxylase, mitochondrial-like; Belongs to the cytochrome P450 family. (517 aa)
dhddsAlkyl transferase; Belongs to the UPP synthase family. (336 aa)
LOC1065317683-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
dhfrDihydrofolate reductase. (189 aa)
sprSepiapterin reductase. (265 aa)
fdpsFarnesyl pyrophosphate synthase isoform X1; Belongs to the FPP/GGPP synthase family. (392 aa)
gbaGlucosylceramidase. (524 aa)
rusc1RUN and SH3 domain-containing protein 1. (1814 aa)
LOC106530854Vitamin D 25-hydroxylase; Belongs to the cytochrome P450 family. (506 aa)
LOC106530689Non-specific serine/threonine protein kinase. (557 aa)
LOC106530620Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (242 aa)
pck2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (634 aa)
pts6-pyruvoyl tetrahydrobiopterin synthase. (237 aa)
lssTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (802 aa)
LOC106529311Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (732 aa)
LOC106528429Pterin-4-alpha-carbinolamine dehydratase 2-like. (128 aa)
hsd17b73-keto-steroid reductase. (345 aa)
isyna1Inositol-3-phosphate synthase 1. (555 aa)
got1Aspartate aminotransferase. (410 aa)
LOC106528220Neutral ceramidase. (623 aa)
ppip5k1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1450 aa)
LOC106526640Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1243 aa)
acer3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
ptafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (419 aa)
asah1Acid ceramidase; Belongs to the acid ceramidase family. (392 aa)
LOC106525612Pterin-4-alpha-carbinolamine dehydratase-like. (102 aa)
tmem130Transmembrane protein 130. (308 aa)
ip6k1Kinase; Belongs to the inositol phosphokinase (IPK) family. (440 aa)
LOC106524717GTP cyclohydrolase 1-like. (298 aa)
ebp3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase. (227 aa)
pck1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (633 aa)
tm7sf2Delta(14)-sterol reductase. (439 aa)
ippkInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (495 aa)
dhcr77-dehydrocholesterol reductase. (472 aa)
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (439 aa)
idi1Isopentenyl-diphosphate Delta-isomerase 1. (227 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (275 aa)
itpkbKinase; Belongs to the inositol phosphokinase (IPK) family. (771 aa)
itpkcKinase; Belongs to the inositol phosphokinase (IPK) family. (651 aa)
LOC106518993Kinase; Belongs to the inositol phosphokinase (IPK) family. (349 aa)
sphk1Sphingosine kinase 1. (323 aa)
LOC106518494Kinase; Belongs to the inositol phosphokinase (IPK) family. (496 aa)
nus1Dehydrodolichyl diphosphate syntase complex subunit NUS1. (288 aa)
LOC106518131Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (497 aa)
LOC10651808425-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (503 aa)
LOC106518001Kinase; Belongs to the inositol phosphokinase (IPK) family. (456 aa)
acer2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (277 aa)
fdft1Squalene synthase isoform X1. (511 aa)
acer1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
r3hdm4R3H domain-containing protein 4. (256 aa)
LOC106516620GTP cyclohydrolase 1-like. (233 aa)
prkaa1Non-specific serine/threonine protein kinase. (573 aa)
nsdhlSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (345 aa)
impa1Inositol-1-monophosphatase. (326 aa)
LOC106515519Inositol-1-monophosphatase. (287 aa)
impad1Inositol monophosphatase 3. (342 aa)
LOC106514613Lathosterol oxidase-like; Belongs to the sterol desaturase family. (236 aa)
LOC106514612Lathosterol oxidase-like; Belongs to the sterol desaturase family. (299 aa)
dbhDopamine beta-hydroxylase. (614 aa)
LOC106514257Sterol 26-hydroxylase, mitochondrial-like; Belongs to the cytochrome P450 family. (508 aa)
LOC106514037Kinase; Belongs to the inositol phosphokinase (IPK) family. (570 aa)
park7Protein deglycase DJ-1. (189 aa)
hmgcs13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (515 aa)
qdprDihydropteridine reductase. (236 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (399 aa)
LOC106512276DBH-like monooxygenase protein 2 homolog. (156 aa)
LOC106511262Sterol 26-hydroxylase, mitochondrial-like; Belongs to the cytochrome P450 family. (461 aa)
LOC106511198Sterol 26-hydroxylase, mitochondrial-like; Belongs to the cytochrome P450 family. (360 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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