(42 nodes) Lateral line system development network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106514007	G-protein coupled receptor 64-like; Belongs to the G-protein coupled receptor 2 family. (1235 aa)
	neurod1	Neurogenic differentiation factor. (340 aa)
	LOC106534837	Protein scribble homolog. (669 aa)
	egr2	E3 SUMO-protein ligase EGR2. (436 aa)
	LOC106534128	Protein scribble homolog. (1512 aa)
	mib1	E3 ubiquitin-protein ligase MIB1 isoform X1. (1041 aa)
	LOC106531705	Mothers against decapentaplegic homolog. (474 aa)
	slc44a4	Choline transporter-like protein 4 isoform X1; Belongs to the CTL (choline transporter-like) family. (719 aa)
	LOC106529794	Fibroblast growth factor receptor. (833 aa)
	LOC106529128	Sphingosine 1-phosphate receptor 2-like; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	abhd12	Monoacylglycerol lipase ABHD12. (372 aa)
	LOC106527636	Transmembrane channel-like protein. (968 aa)
	LOC106527377	Adhesion G-protein coupled receptor G4-like; Belongs to the G-protein coupled receptor 2 family. (770 aa)
	atp6v0d1	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
	phox2b	Paired mesoderm homeobox protein 2B. (285 aa)
	adgrg6	G-protein coupled receptor 126 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1274 aa)
	LOC106523963	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	LOC106523711	Vang-like protein. (526 aa)
	lrrc1	Leucine-rich repeat-containing protein 1. (526 aa)
	LOC106522232	Adhesion G-protein coupled receptor G5-like. (173 aa)
	LOC106522233	G-protein coupled receptor 64-like. (264 aa)
	LOC106522231	G-protein coupled receptor 64-like. (240 aa)
	LOC106521788	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	vangl2	Vang-like protein. (525 aa)
	yap1	Transcriptional coactivator YAP1. (438 aa)
	LOC106520196	Neurogenin-1-like. (181 aa)
	LOC106520108	Transmembrane channel-like protein. (957 aa)
	LOC106520093	Transmembrane channel-like protein. (750 aa)
	znrf3	E3 ubiquitin-protein ligase ZNRF3 isoform X1. (849 aa)
	llgl2	Lethal(2) giant larvae protein homolog 2. (1010 aa)
	gnb1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	LOC106517453	Protein scribble homolog. (550 aa)
	LOC106517263	Transmembrane O-methyltransferase. (274 aa)
	LOC106516123	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like. (340 aa)
	adgrg2	G-protein coupled receptor 64 isoform X1; Belongs to the G-protein coupled receptor 2 family. (574 aa)
	LOC106515044	Protein scribble homolog. (297 aa)
	adgrg4	Adhesion G-protein coupled receptor G4; Belongs to the G-protein coupled receptor 2 family. (1224 aa)
	tmem132e	Transmembrane protein 132E isoform X1. (1088 aa)
	LOC106514214	R-spondin-3-like. (325 aa)
	shtn1	Shootin-1. (496 aa)
	kif1bp	KIF1-binding protein. (631 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106514214	znrf3	A0A2I4ATJ0	A0A2I4BFW4	R-spondin-3-like.	E3 ubiquitin-protein ligase ZNRF3 isoform X1.	0.981
LOC106515044	LOC106523711	A0A2I4AYC1	A0A2I4BY63	Protein scribble homolog.	Vang-like protein.	0.448
LOC106515044	vangl2	A0A2I4AYC1	A0A2I4BL52	Protein scribble homolog.	Vang-like protein.	0.448
LOC106516123	gnb1	A0A2I4B221	A0A2I4BDN4	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.900
LOC106517453	LOC106523711	A0A2I4B7P4	A0A2I4BY63	Protein scribble homolog.	Vang-like protein.	0.448
LOC106517453	LOC106534128	A0A2I4B7P4	A0A2I4D1K2	Protein scribble homolog.	Protein scribble homolog.	0.900
LOC106517453	LOC106534837	A0A2I4B7P4	A0A2I4D4D0	Protein scribble homolog.	Protein scribble homolog.	0.900
LOC106517453	llgl2	A0A2I4B7P4	A0A2I4BDU3	Protein scribble homolog.	Lethal(2) giant larvae protein homolog 2.	0.909
LOC106517453	vangl2	A0A2I4B7P4	A0A2I4BL52	Protein scribble homolog.	Vang-like protein.	0.448
LOC106521788	LOC106523711	A0A2I4BQF9	A0A2I4BY63	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Vang-like protein.	0.444
LOC106521788	LOC106523963	A0A2I4BQF9	A0A2I4BZ43	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.901
LOC106521788	vangl2	A0A2I4BQF9	A0A2I4BL52	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Vang-like protein.	0.444
LOC106523711	LOC106515044	A0A2I4BY63	A0A2I4AYC1	Vang-like protein.	Protein scribble homolog.	0.448
LOC106523711	LOC106517453	A0A2I4BY63	A0A2I4B7P4	Vang-like protein.	Protein scribble homolog.	0.448
LOC106523711	LOC106521788	A0A2I4BY63	A0A2I4BQF9	Vang-like protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.444
LOC106523711	LOC106523963	A0A2I4BY63	A0A2I4BZ43	Vang-like protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.444
LOC106523711	LOC106534128	A0A2I4BY63	A0A2I4D1K2	Vang-like protein.	Protein scribble homolog.	0.448
LOC106523711	LOC106534837	A0A2I4BY63	A0A2I4D4D0	Vang-like protein.	Protein scribble homolog.	0.448
LOC106523711	lrrc1	A0A2I4BY63	A0A2I4BX10	Vang-like protein.	Leucine-rich repeat-containing protein 1.	0.448
LOC106523963	LOC106521788	A0A2I4BZ43	A0A2I4BQF9	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.901