STRINGSTRING
LOC106518869 LOC106518869 LOC106519868 LOC106519868 vegfa vegfa LOC106520808 LOC106520808 pgf pgf LOC106521511 LOC106521511 LOC106521553 LOC106521553 grn grn LOC106522175 LOC106522175 hlx hlx LOC106522503 LOC106522503 LOC106522616 LOC106522616 LOC106523408 LOC106523408 wnt2b wnt2b bad bad LOC106525227 LOC106525227 prok1 prok1 sirt1 sirt1 hpn hpn sirt6 sirt6 nf1 nf1 LOC106526906 LOC106526906 rreb1 rreb1 LOC106527732 LOC106527732 LOC106527856 LOC106527856 LOC106528172 LOC106528172 stxbp4 stxbp4 LOC106530404 LOC106530404 LOC106530462 LOC106530462 LOC106530483 LOC106530483 LOC106530706 LOC106530706 adam17 adam17 LOC106532449 LOC106532449 LOC106532664 LOC106532664 LOC106532969 LOC106532969 ecm1 ecm1 LOC106533460 LOC106533460 st8sia1 st8sia1 fgf1 fgf1 LOC106534447 LOC106534447 LOC106534650 LOC106534650 LOC106534951 LOC106534951 tnfaip3 tnfaip3 LOC106535262 LOC106535262 LOC106535265 LOC106535265 LOC106535653 LOC106535653 smo smo LOC106536610 LOC106536610 xbp1 xbp1 LOC106536951 LOC106536951 bmp4 bmp4 aggf1 aggf1 LOC106518234 LOC106518234 LOC106517635 LOC106517635 med1 med1 LOC106516706 LOC106516706 LOC106516544 LOC106516544 ar ar tgfa tgfa vegfb vegfb igf2 igf2 vip vip sp1 sp1 LOC106514496 LOC106514496 pdx1 pdx1 agtr1 agtr1 il10 il10 map2k5 map2k5 LOC106511991 LOC106511991 mydgf mydgf LOC106511674 LOC106511674 htr2b htr2b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106518869Granulins-like. (586 aa)
LOC106519868Pro-neuregulin-4, membrane-bound isoform-like. (158 aa)
vegfaVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (227 aa)
LOC106520808Junctional protein associated with coronary artery disease-like. (1404 aa)
pgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (163 aa)
LOC106521511Tissue factor-like. (288 aa)
LOC106521553Disintegrin and metalloproteinase domain-containing protein 17-like. (856 aa)
grnGranulins isoform X1. (696 aa)
LOC106522175C5a anaphylatoxin chemotactic receptor 1-like isoform X1. (349 aa)
hlxH2.0-like homeobox protein isoform X1. (382 aa)
LOC106522503Uncharacterized protein LOC106522503 isoform X1; Belongs to the PDGF/VEGF growth factor family. (543 aa)
LOC106522616Leucine-rich alpha-2-glycoprotein-like. (336 aa)
LOC106523408Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (177 aa)
wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
badBcl2-associated agonist of cell death. (165 aa)
LOC106525227Androgen receptor-like isoform X1. (683 aa)
prok1Prokineticin-1. (106 aa)
sirt1NAD-dependent protein deacetylase sirtuin-1. (690 aa)
hpnSerine protease hepsin isoform X1; Belongs to the peptidase S1 family. (490 aa)
sirt6NAD-dependent protein deacetylase sirtuin-6. (349 aa)
nf1Neurofibromin isoform X1. (2016 aa)
LOC106526906LOW QUALITY PROTEIN: regulatory-associated protein of mTOR-like. (1464 aa)
rreb1Ras-responsive element-binding protein 1. (1501 aa)
LOC106527732Granulins-like. (741 aa)
LOC106527856Bone morphogenetic protein 4-like. (513 aa)
LOC106528172Secretogranin-2-like. (598 aa)
stxbp4Syntaxin-binding protein 4. (764 aa)
LOC106530404Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (208 aa)
LOC106530462Granulins-like. (279 aa)
LOC106530483Growth arrest-specific protein 1-like. (249 aa)
LOC106530706Zinc finger protein 703-like. (521 aa)
adam17Disintegrin and metalloproteinase domain-containing protein 17. (842 aa)
LOC106532449Bone morphogenetic protein receptor type-2-like isoform X1. (391 aa)
LOC106532664Fibroblast growth factor-binding protein 1-like. (210 aa)
LOC106532969Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
ecm1Extracellular matrix protein 1. (495 aa)
LOC10653346025-hydroxycholesterol 7-alpha-hydroxylase-like; Belongs to the cytochrome P450 family. (492 aa)
st8sia1alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Belongs to the glycosyltransferase 29 family. (335 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
LOC106534447Transcription factor AP-1-like; Belongs to the bZIP family. (308 aa)
LOC106534650Neurofibromin. (2131 aa)
LOC106534951Secretogranin-2-like. (614 aa)
tnfaip3Tumor necrosis factor alpha-induced protein 3. (815 aa)
LOC106535262Transcription factor jun-D-like. (327 aa)
LOC106535265Regulatory-associated protein of mTOR-like. (387 aa)
LOC106535653Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1057 aa)
smoSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (813 aa)
LOC106536610DNA-binding protein inhibitor ID-1-like. (129 aa)
xbp1LOW QUALITY PROTEIN: X-box-binding protein 1. (378 aa)
LOC106536951Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
aggf1Angiogenic factor with G patch and FHA domains 1. (754 aa)
LOC106518234Toxin MIT1-like. (107 aa)
LOC106517635Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1785 aa)
LOC106516706Apelin receptor A; Belongs to the G-protein coupled receptor 1 family. (360 aa)
LOC106516544Uncharacterized protein LOC106516544 isoform X1; Belongs to the PDGF/VEGF growth factor family. (497 aa)
arAndrogen receptor. (751 aa)
tgfaProtransforming growth factor alpha. (242 aa)
vegfbVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (266 aa)
igf2Insulin-like growth factor II. (215 aa)
vipVIP peptides. (152 aa)
sp1Transcription factor Sp1. (695 aa)
LOC106514496Apelin receptor B-like; Belongs to the G-protein coupled receptor 1 family. (358 aa)
pdx1Pancreas/duodenum homeobox protein 1. (249 aa)
agtr1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (362 aa)
il10Interleukin-10 isoform X1. (259 aa)
map2k5Dual specificity mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (443 aa)
LOC106511991Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (160 aa)
mydgfMyeloid-derived growth factor. (196 aa)
LOC106511674Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (677 aa)
htr2b5-hydroxytryptamine receptor 2B. (466 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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