(36 nodes) Regulation of steroid biosynthetic process network (Austrofundulus limnaeus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	LOC106524682	Nuclear receptor subfamily 1 group D member 1-like. (574 aa)
	LOC106536525	LOW QUALITY PROTEIN: leptin-like. (198 aa)
	LOC106536197	Dickkopf-related protein 3-like. (263 aa)
	LOC106535839	Nuclear receptor subfamily 0 group B member 1-like. (298 aa)
	abcg1	ATP-binding cassette sub-family G member 1. (685 aa)
	LOC106535459	Sterol regulatory element-binding protein cleavage-activating protein-like. (1274 aa)
	dab2	Disabled homolog 2 isoform X1. (739 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
	LOC106534304	Apolipoprotein B-100-like. (3309 aa)
	snai2	Zinc finger protein SNAI2. (260 aa)
	LOC106533540	Sterol regulatory element-binding protein 1-like. (287 aa)
	rusc1	RUN and SH3 domain-containing protein 1. (1814 aa)
	LOC106531362	Splicing factor 1-like. (547 aa)
	LOC106531282	Dickkopf-related protein 3-like. (261 aa)
	dgkq	Diacylglycerol kinase. (935 aa)
	apoe	Apolipoprotein E. (251 aa)
	armc5	Armadillo repeat-containing protein 5. (1194 aa)
	podn	Podocan. (593 aa)
	LOC106528070	Nuclear receptor subfamily 1 group D member 1-like. (570 aa)
	scap	Sterol regulatory element-binding protein cleavage-activating protein. (1360 aa)
	fgf19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
	asah1	Acid ceramidase; Belongs to the acid ceramidase family. (392 aa)
	sirt1	NAD-dependent protein deacetylase sirtuin-1. (690 aa)
	LOC106523750	Apolipoprotein Eb-like. (265 aa)
	LOC106523408	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (177 aa)
	apob	Apolipoprotein B-100 isoform X1. (3804 aa)
	srebf1	Sterol regulatory element-binding protein 1. (1170 aa)
	cga	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (124 aa)
	LOC106521237	Apolipoprotein B-100-like isoform X1. (4384 aa)
	lpcat3	Lysophospholipid acyltransferase 5 isoform X1; Belongs to the membrane-bound acyltransferase family. (465 aa)
	srebf2	Sterol regulatory element-binding protein 2. (1175 aa)
	LOC106516561	Steroidogenic acute regulatory protein, mitochondrial-like. (272 aa)
	abcg4	ATP-binding cassette sub-family G member 4. (641 aa)
	h6pd	GDH/6PGL endoplasmic bifunctional protein. (791 aa)
	igf2	Insulin-like growth factor II. (215 aa)
	LOC106511089	Splicing factor 1-like. (677 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106516561	LOC106535839	A0A2I4B3X6	A0A2I4D856	Steroidogenic acute regulatory protein, mitochondrial-like.	Nuclear receptor subfamily 0 group B member 1-like.	0.566
LOC106521237	LOC106523750	A0A2I4BN50	A0A2I4BYB0	Apolipoprotein B-100-like isoform X1.	Apolipoprotein Eb-like.	0.780
LOC106521237	apoe	A0A2I4BN50	A0A2I4CMA5	Apolipoprotein B-100-like isoform X1.	Apolipoprotein E.	0.702
LOC106521237	dab2	A0A2I4BN50	A0A2I4D3S0	Apolipoprotein B-100-like isoform X1.	Disabled homolog 2 isoform X1.	0.518
LOC106523408	fgf19	A0A2I4BWZ4	A0A2I4C9I6	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.506
LOC106523750	LOC106521237	A0A2I4BYB0	A0A2I4BN50	Apolipoprotein Eb-like.	Apolipoprotein B-100-like isoform X1.	0.780
LOC106523750	LOC106534304	A0A2I4BYB0	A0A2I4D288	Apolipoprotein Eb-like.	Apolipoprotein B-100-like.	0.780
LOC106523750	apob	A0A2I4BYB0	A0A2I4BTW0	Apolipoprotein Eb-like.	Apolipoprotein B-100 isoform X1.	0.780
LOC106523750	asah1	A0A2I4BYB0	A0A2I4C6P1	Apolipoprotein Eb-like.	Acid ceramidase; Belongs to the acid ceramidase family.	0.468
LOC106533540	LOC106535459	A0A2I4CZB4	A0A2I4D6Q3	Sterol regulatory element-binding protein 1-like.	Sterol regulatory element-binding protein cleavage-activating protein-like.	0.851
LOC106533540	scap	A0A2I4CZB4	A0A2I4CA36	Sterol regulatory element-binding protein 1-like.	Sterol regulatory element-binding protein cleavage-activating protein.	0.851
LOC106533540	sirt1	A0A2I4CZB4	A0A2I4C5T8	Sterol regulatory element-binding protein 1-like.	NAD-dependent protein deacetylase sirtuin-1.	0.447
LOC106534304	LOC106523750	A0A2I4D288	A0A2I4BYB0	Apolipoprotein B-100-like.	Apolipoprotein Eb-like.	0.780
LOC106534304	apoe	A0A2I4D288	A0A2I4CMA5	Apolipoprotein B-100-like.	Apolipoprotein E.	0.702
LOC106534304	dab2	A0A2I4D288	A0A2I4D3S0	Apolipoprotein B-100-like.	Disabled homolog 2 isoform X1.	0.518
LOC106535459	LOC106533540	A0A2I4D6Q3	A0A2I4CZB4	Sterol regulatory element-binding protein cleavage-activating protein-like.	Sterol regulatory element-binding protein 1-like.	0.851
LOC106535459	srebf1	A0A2I4D6Q3	A0A2I4BRI0	Sterol regulatory element-binding protein cleavage-activating protein-like.	Sterol regulatory element-binding protein 1.	0.851
LOC106535459	srebf2	A0A2I4D6Q3	A0A2I4BKV7	Sterol regulatory element-binding protein cleavage-activating protein-like.	Sterol regulatory element-binding protein 2.	0.851
LOC106535839	LOC106516561	A0A2I4D856	A0A2I4B3X6	Nuclear receptor subfamily 0 group B member 1-like.	Steroidogenic acute regulatory protein, mitochondrial-like.	0.566
LOC106536525	igf2	A0A2I4DAK8	A0A2I4AZV3	LOW QUALITY PROTEIN: leptin-like.	Insulin-like growth factor II.	0.474