(18 nodes) Defense response to Gram-negative bacterium network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106516110	Tumor suppressor candidate 2-like. (111 aa)
	LOC106533500	Tumor necrosis factor receptor superfamily member 5-like. (212 aa)
	LOC106533179	Aquaporin-1-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	LOC106533171	Aquaporin FA-CHIP-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (280 aa)
	chga	chromogranin-A. (364 aa)
	LOC106531425	interleukin-17F-like. (154 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (621 aa)
	LOC106531153	interleukin-17F-like. (160 aa)
	LOC106531145	interleukin-17A-like. (119 aa)
	LOC106531146	interleukin-17A-like. (123 aa)
	LOC106530044	Bactericidal permeability-increasing protein-like. (472 aa)
	serpine1	Plasminogen activator inhibitor 1; Belongs to the serpin family. (391 aa)
	LOC106524033	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (318 aa)
	drosha	Ribonuclease 3. (1336 aa)
	LOC106511502	Tumor necrosis factor receptor superfamily member 14-like. (164 aa)
	mpeg1	Macrophage-expressed gene 1 protein. (703 aa)
	rpl30	60S ribosomal protein L30. (116 aa)
	tusc2	Tumor suppressor candidate 2. (109 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106531145	LOC106531146	A0A2I4CQW9	A0A2I4CQW6	interleukin-17A-like.	interleukin-17A-like.	0.900
LOC106531145	LOC106531153	A0A2I4CQW9	A0A2I4CQX4	interleukin-17A-like.	interleukin-17F-like.	0.433
LOC106531145	LOC106531425	A0A2I4CQW9	A0A2I4CRX9	interleukin-17A-like.	interleukin-17F-like.	0.453
LOC106531146	LOC106531145	A0A2I4CQW6	A0A2I4CQW9	interleukin-17A-like.	interleukin-17A-like.	0.900
LOC106531146	LOC106531153	A0A2I4CQW6	A0A2I4CQX4	interleukin-17A-like.	interleukin-17F-like.	0.432
LOC106531146	LOC106531425	A0A2I4CQW6	A0A2I4CRX9	interleukin-17A-like.	interleukin-17F-like.	0.450
LOC106531153	LOC106531145	A0A2I4CQX4	A0A2I4CQW9	interleukin-17F-like.	interleukin-17A-like.	0.433
LOC106531153	LOC106531146	A0A2I4CQX4	A0A2I4CQW6	interleukin-17F-like.	interleukin-17A-like.	0.432
LOC106531153	LOC106531425	A0A2I4CQX4	A0A2I4CRX9	interleukin-17F-like.	interleukin-17F-like.	0.907
LOC106531425	LOC106531145	A0A2I4CRX9	A0A2I4CQW9	interleukin-17F-like.	interleukin-17A-like.	0.453
LOC106531425	LOC106531146	A0A2I4CRX9	A0A2I4CQW6	interleukin-17F-like.	interleukin-17A-like.	0.450
LOC106531425	LOC106531153	A0A2I4CRX9	A0A2I4CQX4	interleukin-17F-like.	interleukin-17F-like.	0.907
f2	serpine1	A0A2I4CRB0	A0A2I4CB05	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen activator inhibitor 1; Belongs to the serpin family.	0.496
serpine1	f2	A0A2I4CB05	A0A2I4CRB0	Plasminogen activator inhibitor 1; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.496