(33 nodes) Endocrine process network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106530112	Endothelin-3-like. (219 aa)
	oxtr	Oxytocin receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (394 aa)
	LOC106518250	Vasopressin V2 receptor-like. (358 aa)
	tmf1	TATA element modulatory factor. (1153 aa)
	LOC106520180	Alpha-2-antiplasmin-like; Belongs to the serpin family. (480 aa)
	enpep	Aminopeptidase. (956 aa)
	fzd4	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
	LOC106523524	Vasopressin V1a receptor-like. (305 aa)
	LOC106523540	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family. (667 aa)
	LOC106523783	Selenoprotein M-like. (191 aa)
	LOC106524760	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	avpr2	Vasopressin V2 receptor isoform X1. (514 aa)
	LOC106529550	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family. (511 aa)
	LOC106530016	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	LOC106518019	Vasopressin V2 receptor-like. (353 aa)
	corin	Atrial natriuretic peptide-converting enzyme. (921 aa)
	LOC106531197	Arg8-vasotocin receptor-like. (409 aa)
	LOC106531877	Vasopressin V2 receptor-like. (438 aa)
	avpr1a	Vasopressin V1a receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (405 aa)
	serpinf2	Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (514 aa)
	LOC106535188	Angiotensin-converting enzyme. (701 aa)
	LOC106533179	Aquaporin-1-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	LOC106533171	Aquaporin FA-CHIP-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (280 aa)
	LOC106534610	Endothelin-2-like. (157 aa)
	LOC106533767	Potassium voltage-gated channel subfamily KQT member 1-like. (226 aa)
	LOC106511782	Atrial natriuretic peptide-converting enzyme-like. (114 aa)
	LOC106511940	Atrial natriuretic peptide-converting enzyme-like; Belongs to the peptidase S1 family. (312 aa)
	LOC106512451	Atrial natriuretic peptide-converting enzyme-like. (202 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (460 aa)
	agtr1	Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	LOC106513815	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (419 aa)
	LOC106516075	Isotocin receptor-like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (395 aa)
	ace	Angiotensin-converting enzyme. (1147 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106513815	LOC106524760	A0A2I4AS12	A0A2I4C2D6	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.901
LOC106513815	LOC106530016	A0A2I4AS12	A0A2I4CM05	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.901
LOC106513815	LOC106530112	A0A2I4AS12	A0A2I4CMD1	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-3-like.	0.993
LOC106513815	LOC106534610	A0A2I4AS12	A0A2I4D3D8	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-2-like.	0.828
LOC106513815	agt	A0A2I4AS12	A0A2I4ANU5	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Angiotensinogen; Belongs to the serpin family.	0.565
LOC106516075	LOC106530112	A0A2I4B1U3	A0A2I4CMD1	Isotocin receptor-like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Endothelin-3-like.	0.541
LOC106516075	oxtr	A0A2I4B1U3	A0A2I4B9V5	Isotocin receptor-like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Oxytocin receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.901
LOC106518019	LOC106530112	A0A2I4B9V4	A0A2I4CMD1	Vasopressin V2 receptor-like.	Endothelin-3-like.	0.541
LOC106518250	LOC106530112	A0A2I4BB05	A0A2I4CMD1	Vasopressin V2 receptor-like.	Endothelin-3-like.	0.541
LOC106523524	LOC106530112	A0A2I4BXE9	A0A2I4CMD1	Vasopressin V1a receptor-like.	Endothelin-3-like.	0.541
LOC106523540	LOC106529550	A0A2I4BXG2	A0A2I4CKF1	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	0.903
LOC106524760	LOC106513815	A0A2I4C2D6	A0A2I4AS12	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.901
LOC106524760	LOC106530016	A0A2I4C2D6	A0A2I4CM05	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.901
LOC106524760	LOC106530112	A0A2I4C2D6	A0A2I4CMD1	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-3-like.	0.993
LOC106524760	LOC106534610	A0A2I4C2D6	A0A2I4D3D8	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-2-like.	0.828
LOC106524760	agt	A0A2I4C2D6	A0A2I4ANU5	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Angiotensinogen; Belongs to the serpin family.	0.565
LOC106529550	LOC106523540	A0A2I4CKF1	A0A2I4BXG2	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	0.903
LOC106530016	LOC106513815	A0A2I4CM05	A0A2I4AS12	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.901
LOC106530016	LOC106524760	A0A2I4CM05	A0A2I4C2D6	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.901
LOC106530016	LOC106530112	A0A2I4CM05	A0A2I4CMD1	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-3-like.	0.993