(37 nodes) Regulation of filopodium assembly network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fnbp1l	Formin-binding protein 1-like. (563 aa)
	LOC106531534	Fragile X mental retardation syndrome-related protein 1 homolog B-like isoform X1. (1188 aa)
	bcas3	Breast carcinoma-amplified sequence 3. (934 aa)
	LOC106535670	Dihydropyrimidinase-related protein 3. (575 aa)
	LOC106535680	Teneurin-1-like. (849 aa)
	LOC106536374	Fragile X mental retardation protein 1 homolog B-like. (621 aa)
	LOC106536703	Serum response factor-like. (519 aa)
	LOC106510847	Serum response factor-like. (385 aa)
	LOC106511336	Breast carcinoma-amplified sequence 3-like. (107 aa)
	palm	Paralemmin-1. (377 aa)
	LOC106512494	Breast carcinoma-amplified sequence 3-like. (137 aa)
	myo3b	myosin-IIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1313 aa)
	gpm6a	Neuronal membrane glycoprotein M6-a. (278 aa)
	fam206a	Protein Simiate isoform X1. (195 aa)
	fam65b	Protein FAM65B isoform X1. (1126 aa)
	capzb	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
	prkcd	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	LOC106518511	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	LOC106518576	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	agrn	Agrin. (1889 aa)
	LOC106519316	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC106519594	Cell division control protein 42 homolog. (191 aa)
	LOC106520967	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	LOC106518902	Agrin-like. (226 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (881 aa)
	srf	Serum response factor isoform X1. (485 aa)
	fam65c	Protein FAM65C. (999 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (824 aa)
	LOC106526649	Paralemmin-1-like. (219 aa)
	LOC106527048	Migration and invasion enhancer 1-like. (83 aa)
	LOC106527240	Teneurin-1-like. (2231 aa)
	LOC106527332	Migration and invasion enhancer 1-like. (95 aa)
	LOC106527434	Fragile X mental retardation protein 1 homolog. (414 aa)
	fxr2	Fragile X mental retardation syndrome-related protein 2 isoform X1. (678 aa)
	LOC106528512	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC106529148	Cell division control protein 42 homolog. (191 aa)
	LOC106530407	Breast carcinoma-amplified sequence 3 homolog. (517 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106510847	LOC106536703	A0A2I4AHR9	A0A2I4DB71	Serum response factor-like.	Serum response factor-like.	0.902
LOC106510847	srf	A0A2I4AHR9	A0A2I4BS82	Serum response factor-like.	Serum response factor isoform X1.	0.901
LOC106511336	LOC106512494	A0A2I4AJ92	A0A2I4AM21	Breast carcinoma-amplified sequence 3-like.	Breast carcinoma-amplified sequence 3-like.	0.621
LOC106512494	LOC106511336	A0A2I4AM21	A0A2I4AJ92	Breast carcinoma-amplified sequence 3-like.	Breast carcinoma-amplified sequence 3-like.	0.621
LOC106518576	LOC106520967	A0A2I4BC99	A0A2I4BLY9	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.900
LOC106518902	agrn	A0A2I4BDH7	A0A2I4BDH0	Agrin-like.	Agrin.	0.898
LOC106519316	capzb	A0A2I4BF52	A0A2I4B241	Cell division control protein 42 homolog isoform X1.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.492
LOC106519316	fnbp1l	A0A2I4BF52	A0A2I4CRC2	Cell division control protein 42 homolog isoform X1.	Formin-binding protein 1-like.	0.751
LOC106519594	capzb	A0A2I4BGB5	A0A2I4B241	Cell division control protein 42 homolog.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.480
LOC106519594	fnbp1l	A0A2I4BGB5	A0A2I4CRC2	Cell division control protein 42 homolog.	Formin-binding protein 1-like.	0.472
LOC106520967	LOC106518576	A0A2I4BLY9	A0A2I4BC99	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family.	0.900
LOC106527434	LOC106531534	A0A2I4CCQ6	A0A2I4CSA7	Fragile X mental retardation protein 1 homolog.	Fragile X mental retardation syndrome-related protein 1 homolog B-like isoform X1.	0.565
LOC106527434	fxr2	A0A2I4CCQ6	A0A2I4CEH0	Fragile X mental retardation protein 1 homolog.	Fragile X mental retardation syndrome-related protein 2 isoform X1.	0.567
LOC106528512	capzb	A0A2I4CGM8	A0A2I4B241	Cell division control protein 42 homolog isoform X1.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.492
LOC106528512	fnbp1l	A0A2I4CGM8	A0A2I4CRC2	Cell division control protein 42 homolog isoform X1.	Formin-binding protein 1-like.	0.751
LOC106529148	capzb	A0A2I4CIX2	A0A2I4B241	Cell division control protein 42 homolog.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.480
LOC106529148	fnbp1l	A0A2I4CIX2	A0A2I4CRC2	Cell division control protein 42 homolog.	Formin-binding protein 1-like.	0.472
LOC106531534	LOC106527434	A0A2I4CSA7	A0A2I4CCQ6	Fragile X mental retardation syndrome-related protein 1 homolog B-like isoform X1.	Fragile X mental retardation protein 1 homolog.	0.565
LOC106531534	LOC106536374	A0A2I4CSA7	A0A2I4DA24	Fragile X mental retardation syndrome-related protein 1 homolog B-like isoform X1.	Fragile X mental retardation protein 1 homolog B-like.	0.567
LOC106536374	LOC106531534	A0A2I4DA24	A0A2I4CSA7	Fragile X mental retardation protein 1 homolog B-like.	Fragile X mental retardation syndrome-related protein 1 homolog B-like isoform X1.	0.567