(23 nodes) Regulation of cardiac muscle contraction network (Austrofundulus limnaeus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Predicted Interactions

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Your Input:
	pkd2	Polycystin-2 isoform X1. (898 aa)
	LOC106535805	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (222 aa)
	LOC106536002	Ribonuclease ZC3H12A-like. (422 aa)
	LOC106530460	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1. (1139 aa)
	LOC106518776	Junction plakoglobin-like. (723 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC106517961	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (183 aa)
	ankrd28	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A. (1052 aa)
	ucn	Urocortin. (138 aa)
	LOC106529550	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family. (511 aa)
	LOC106529254	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (395 aa)
	LOC106527763	Grancalcin-like. (245 aa)
	LOC106526625	Ribonuclease ZC3H12A-like. (593 aa)
	LOC106523540	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family. (667 aa)
	ankrd52	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X1. (1089 aa)
	rnf207	RING finger protein 207. (616 aa)
	gja5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
	ankrd44	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B. (1072 aa)
	ankrd66	Ankyrin repeat domain-containing protein 66. (162 aa)
	LOC106533481	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like. (1047 aa)
	LOC106533767	Potassium voltage-gated channel subfamily KQT member 1-like. (226 aa)
	sri	Sorcin. (184 aa)
	pln	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106517961	LOC106518776	A0A2I4B9R0	A0A2I4BD14	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin-like.	0.463
LOC106517961	cav3	A0A2I4B9R0	A0A2I4B9X1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.592
LOC106518776	LOC106517961	A0A2I4BD14	A0A2I4B9R0	Junction plakoglobin-like.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.463
LOC106518776	LOC106535805	A0A2I4BD14	A0A2I4D7Y4	Junction plakoglobin-like.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.463
LOC106518776	cav3	A0A2I4BD14	A0A2I4B9X1	Junction plakoglobin-like.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.542
LOC106523540	LOC106529550	A0A2I4BXG2	A0A2I4CKF1	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	0.903
LOC106529550	LOC106523540	A0A2I4CKF1	A0A2I4BXG2	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily KQT member 1-like; Belongs to the potassium channel family.	0.903
LOC106535805	LOC106518776	A0A2I4D7Y4	A0A2I4BD14	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin-like.	0.463
LOC106535805	cav3	A0A2I4D7Y4	A0A2I4B9X1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.572
cav3	LOC106517961	A0A2I4B9X1	A0A2I4B9R0	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.592
cav3	LOC106518776	A0A2I4B9X1	A0A2I4BD14	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin-like.	0.542
cav3	LOC106535805	A0A2I4B9X1	A0A2I4D7Y4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.572