(20 nodes) Pharyngeal system development network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106536951	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
	LOC106511674	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (677 aa)
	LOC106511991	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (160 aa)
	dlx2	Homeobox protein DLX-2. (276 aa)
	LOC106514226	Double-strand-break repair protein rad21 homolog. (637 aa)
	LOC106514699	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (462 aa)
	LOC106515330	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	LOC106520416	Homeobox protein Nkx-3.1-like. (193 aa)
	tbx1	T-box transcription factor TBX1 isoform X1. (521 aa)
	LOC106526946	Homeobox protein BarH-like 1. (230 aa)
	kctd15	BTB/POZ domain-containing protein KCTD15 isoform X1. (385 aa)
	ednra	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (437 aa)
	LOC106530112	Endothelin-3-like. (219 aa)
	tbx10	T-box transcription factor TBX10. (317 aa)
	rad21	Double-strand-break repair protein rad21 homolog. (539 aa)
	LOC106531025	BTB/POZ domain-containing protein kctd15-like. (266 aa)
	LOC106531229	Double-strand-break repair protein rad21 homolog isoform X1. (542 aa)
	LOC106531705	Mothers against decapentaplegic homolog. (474 aa)
	LOC106532449	Bone morphogenetic protein receptor type-2-like isoform X1. (391 aa)
	LOC106535653	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1057 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511674	LOC106531705	A0A2I4AK77	A0A2I4CSW1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.482
LOC106511674	LOC106535653	A0A2I4AK77	A0A2I4D7F0	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.901
LOC106511674	LOC106536951	A0A2I4AK77	A0A2I4DC05	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.901
LOC106511991	LOC106531705	A0A2I4AL03	A0A2I4CSW1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.482
LOC106514226	LOC106531229	A0A2I4ATM5	A0A2I4CR58	Double-strand-break repair protein rad21 homolog.	Double-strand-break repair protein rad21 homolog isoform X1.	0.902
LOC106514226	rad21	A0A2I4ATM5	A0A2I4CPG6	Double-strand-break repair protein rad21 homolog.	Double-strand-break repair protein rad21 homolog.	0.901
LOC106514699	LOC106530112	A0A2I4AVN4	A0A2I4CMD1	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-3-like.	0.996
LOC106514699	ednra	A0A2I4AVN4	A0A2I4CD60	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	0.901
LOC106515330	LOC106526946	A0A2I4AYE0	A0A2I4CAW3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein BarH-like 1.	0.405
LOC106515330	LOC106530112	A0A2I4AYE0	A0A2I4CMD1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Endothelin-3-like.	0.563
LOC106515330	dlx2	A0A2I4AYE0	A0A2I4AMI4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein DLX-2.	0.408
LOC106526946	LOC106515330	A0A2I4CAW3	A0A2I4AYE0	Homeobox protein BarH-like 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.405
LOC106526946	ednra	A0A2I4CAW3	A0A2I4CD60	Homeobox protein BarH-like 1.	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	0.404
LOC106530112	LOC106514699	A0A2I4CMD1	A0A2I4AVN4	Endothelin-3-like.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.996
LOC106530112	LOC106515330	A0A2I4CMD1	A0A2I4AYE0	Endothelin-3-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.563
LOC106530112	ednra	A0A2I4CMD1	A0A2I4CD60	Endothelin-3-like.	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	0.997
LOC106531229	LOC106514226	A0A2I4CR58	A0A2I4ATM5	Double-strand-break repair protein rad21 homolog isoform X1.	Double-strand-break repair protein rad21 homolog.	0.902
LOC106531229	rad21	A0A2I4CR58	A0A2I4CPG6	Double-strand-break repair protein rad21 homolog isoform X1.	Double-strand-break repair protein rad21 homolog.	0.904
LOC106531705	LOC106511674	A0A2I4CSW1	A0A2I4AK77	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.482
LOC106531705	LOC106511991	A0A2I4CSW1	A0A2I4AL03	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.482