(14 nodes) Positive regulation of pattern recognition receptor signaling pathway network (Austrofundulus limnaeus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	slc15a4	Solute carrier family 15 member 4 isoform X1. (563 aa)
	LOC106513204	Cytochrome b-245 light chain. (213 aa)
	slc46a2	Thymic stromal cotransporter homolog. (322 aa)
	mfhas1	Malignant fibrous histiocytoma-amplified sequence 1. (1028 aa)
	LOC106535805	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (222 aa)
	LOC106534306	Pumilio homolog 2-like isoform X1. (1208 aa)
	LOC106532847	Toll-like receptor 5. (654 aa)
	tirap	Toll/interleukin-1 receptor domain-containing adapter protein. (186 aa)
	dhx58	Probable ATP-dependent RNA helicase DHX58. (681 aa)
	tlr5	Toll-like receptor 5; Belongs to the Toll-like receptor family. (880 aa)
	ifi35	Interferon-induced 35 kDa protein. (372 aa)
	LOC106519860	Uncharacterized protein CXorf21 homolog. (317 aa)
	LOC106517961	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (183 aa)
	pum1	Pumilio homolog 1 isoform X1. (1165 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106519860	slc15a4	A0A2I4BHD8	A0A2I4B4F2	Uncharacterized protein CXorf21 homolog.	Solute carrier family 15 member 4 isoform X1.	0.465
LOC106532847	tirap	A0A2I4CWR7	A0A2I4CTR5	Toll-like receptor 5.	Toll/interleukin-1 receptor domain-containing adapter protein.	0.591
LOC106532847	tlr5	A0A2I4CWR7	A0A2I4CAP5	Toll-like receptor 5.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.903
dhx58	ifi35	A0A2I4CEW3	A0A2I4C2L7	Probable ATP-dependent RNA helicase DHX58.	Interferon-induced 35 kDa protein.	0.666
ifi35	dhx58	A0A2I4C2L7	A0A2I4CEW3	Interferon-induced 35 kDa protein.	Probable ATP-dependent RNA helicase DHX58.	0.666
slc15a4	LOC106519860	A0A2I4B4F2	A0A2I4BHD8	Solute carrier family 15 member 4 isoform X1.	Uncharacterized protein CXorf21 homolog.	0.465
tirap	LOC106532847	A0A2I4CTR5	A0A2I4CWR7	Toll/interleukin-1 receptor domain-containing adapter protein.	Toll-like receptor 5.	0.591
tirap	tlr5	A0A2I4CTR5	A0A2I4CAP5	Toll/interleukin-1 receptor domain-containing adapter protein.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.591
tlr5	LOC106532847	A0A2I4CAP5	A0A2I4CWR7	Toll-like receptor 5; Belongs to the Toll-like receptor family.	Toll-like receptor 5.	0.903
tlr5	tirap	A0A2I4CAP5	A0A2I4CTR5	Toll-like receptor 5; Belongs to the Toll-like receptor family.	Toll/interleukin-1 receptor domain-containing adapter protein.	0.591