(25 nodes) Cellular response to hydrogen peroxide network (Austrofundulus limnaeus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106511039	Protein IMPACT-like. (318 aa)
	LOC106511439	Zinc finger protein 277-like. (270 aa)
	LOC106511621	Zinc finger protein 277-like. (131 aa)
	LOC106512584	Zinc finger protein 277-like. (272 aa)
	nfe2l2	Nuclear factor erythroid 2-related factor 2. (606 aa)
	trpa1	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1118 aa)
	park7	Protein deglycase DJ-1. (189 aa)
	aifm1	Apoptosis-inducing factor 1, mitochondrial isoform X1. (644 aa)
	ect2	Protein ECT2 isoform X1. (1117 aa)
	ankzf1	Ankyrin repeat and zinc finger domain-containing protein 1 isoform X1. (736 aa)
	sirt1	NAD-dependent protein deacetylase sirtuin-1. (690 aa)
	LOC106525583	Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (537 aa)
	LOC106527055	Receptor-interacting serine/threonine-protein kinase 3-like; Belongs to the protein kinase superfamily. (481 aa)
	plekha1	Pleckstrin homology domain-containing family A member 1. (301 aa)
	LOC106530112	Endothelin-3-like. (219 aa)
	oser1	Oxidative stress-responsive serine-rich protein 1. (326 aa)
	LOC106531352	E3 ubiquitin-protein ligase RBBP6-like. (1710 aa)
	fxn	Frataxin, mitochondrial. (197 aa)
	LOC106532001	Protein IMPACT-like. (319 aa)
	LOC106533171	Aquaporin FA-CHIP-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (280 aa)
	LOC106533179	Aquaporin-1-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	ripk1	Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (743 aa)
	LOC106533946	Lysine-specific demethylase 6B-like. (1304 aa)
	tnfaip3	Tumor necrosis factor alpha-induced protein 3. (815 aa)
	smpd3	Sphingomyelin phosphodiesterase 3. (735 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511439	LOC106511621	A0A2I4AJJ2	A0A2I4AK15	Zinc finger protein 277-like.	Zinc finger protein 277-like.	0.825
LOC106511621	LOC106511439	A0A2I4AK15	A0A2I4AJJ2	Zinc finger protein 277-like.	Zinc finger protein 277-like.	0.825
LOC106527055	ripk1	A0A2I4CBA7	A0A2I4D0Q0	Receptor-interacting serine/threonine-protein kinase 3-like; Belongs to the protein kinase superfamily.	Receptor-interacting serine/threonine-protein kinase 1 isoform X1.	0.999
LOC106527055	tnfaip3	A0A2I4CBA7	A0A2I4D5I9	Receptor-interacting serine/threonine-protein kinase 3-like; Belongs to the protein kinase superfamily.	Tumor necrosis factor alpha-induced protein 3.	0.952
nfe2l2	sirt1	A0A2I4AMY0	A0A2I4C5T8	Nuclear factor erythroid 2-related factor 2.	NAD-dependent protein deacetylase sirtuin-1.	0.408
ripk1	LOC106527055	A0A2I4D0Q0	A0A2I4CBA7	Receptor-interacting serine/threonine-protein kinase 1 isoform X1.	Receptor-interacting serine/threonine-protein kinase 3-like; Belongs to the protein kinase superfamily.	0.999
ripk1	tnfaip3	A0A2I4D0Q0	A0A2I4D5I9	Receptor-interacting serine/threonine-protein kinase 1 isoform X1.	Tumor necrosis factor alpha-induced protein 3.	0.947
sirt1	nfe2l2	A0A2I4C5T8	A0A2I4AMY0	NAD-dependent protein deacetylase sirtuin-1.	Nuclear factor erythroid 2-related factor 2.	0.408
tnfaip3	LOC106527055	A0A2I4D5I9	A0A2I4CBA7	Tumor necrosis factor alpha-induced protein 3.	Receptor-interacting serine/threonine-protein kinase 3-like; Belongs to the protein kinase superfamily.	0.952
tnfaip3	ripk1	A0A2I4D5I9	A0A2I4D0Q0	Tumor necrosis factor alpha-induced protein 3.	Receptor-interacting serine/threonine-protein kinase 1 isoform X1.	0.947