(40 nodes) Leukocyte proliferation network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	il34	Interleukin-34. (311 aa)
	LOC106535238	Tumor necrosis factor ligand superfamily member 15-like; Belongs to the tumor necrosis factor family. (137 aa)
	LOC106534939	Roquin-1-like isoform X1. (1122 aa)
	LOC106534650	Neurofibromin. (2131 aa)
	LOC106531985	Tumor necrosis factor receptor superfamily member 5-like. (305 aa)
	npr3	Atrial natriuretic peptide receptor 3 isoform X1. (498 aa)
	ripk2	Receptor-interacting serine/threonine-protein kinase 2 isoform X1. (577 aa)
	LOC106529655	Transforming growth factor beta-1-like. (474 aa)
	armc5	Armadillo repeat-containing protein 5. (1194 aa)
	malt1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (829 aa)
	LOC106527579	Interleukin-7 receptor subunit alpha-like. (456 aa)
	LOC106526938	Transcription factor jun-B-like isoform X1. (332 aa)
	nf1	Neurofibromin isoform X1. (2016 aa)
	LOC106526427	Thioredoxin; Belongs to the thioredoxin family. (106 aa)
	LOC106526428	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	LOC106524441	Ras association domain-containing protein 5-like. (252 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (824 aa)
	tnfsf13b	Tumor necrosis factor ligand superfamily member 13B isoform X1; Belongs to the tumor necrosis factor family. (272 aa)
	cd79a	B-cell antigen receptor complex-associated protein alpha chain. (221 aa)
	LOC106523044	Uncharacterized protein LOC106523044 isoform X1. (272 aa)
	LOC106522383	E3 ubiquitin-protein ligase. (877 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (576 aa)
	LOC106521563	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog. (831 aa)
	ncstn	Nicastrin isoform X1. (701 aa)
	card11	Caspase recruitment domain-containing protein 11 isoform X1. (1155 aa)
	ebi3	Interleukin-27 subunit beta. (251 aa)
	LOC106518511	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	prkcd	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	LOC106517855	Transcription factor jun-B-like. (330 aa)
	itch	E3 ubiquitin-protein ligase. (864 aa)
	lef1	Lymphoid enhancer-binding factor 1 isoform X1. (380 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (827 aa)
	ptprc	Receptor-type tyrosine-protein phosphatase C. (863 aa)
	sash3	SAM and SH3 domain-containing protein 3. (387 aa)
	LOC106514548	Roquin-2-like isoform X1. (1154 aa)
	LOC106514346	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (648 aa)
	azi2	5-azacytidine-induced protein 2 isoform X1. (400 aa)
	hells	Lymphoid-specific helicase. (851 aa)
	rassf5	Ras association domain-containing protein 5 isoform X1. (534 aa)
	LOC106511186	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family. (263 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511186	LOC106523044	A0A2I4AIS2	A0A2I4BVK5	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Uncharacterized protein LOC106523044 isoform X1.	0.591
LOC106511186	LOC106531985	A0A2I4AIS2	A0A2I4CTT3	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily member 5-like.	0.812
LOC106511186	LOC106535238	A0A2I4AIS2	A0A2I4D601	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand superfamily member 15-like; Belongs to the tumor necrosis factor family.	0.605
LOC106511186	tnfsf13b	A0A2I4AIS2	A0A2I4BYX5	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand superfamily member 13B isoform X1; Belongs to the tumor necrosis factor family.	0.799
LOC106514346	LOC106518511	A0A2I4AU54	A0A2I4BC02	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.447
LOC106514346	LOC106521563	A0A2I4AU54	A0A2I4BPK3	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog.	0.906
LOC106514346	card11	A0A2I4AU54	A0A2I4BKP8	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	Caspase recruitment domain-containing protein 11 isoform X1.	0.860
LOC106514346	malt1	A0A2I4AU54	A0A2I4CI63	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1.	0.902
LOC106514346	prkcd	A0A2I4AU54	A0A2I4BA02	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.447
LOC106514346	prkcq	A0A2I4AU54	A0A2I4C126	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.447
LOC106514548	LOC106534939	A0A2I4AUZ3	A0A2I4D4N9	Roquin-2-like isoform X1.	Roquin-1-like isoform X1.	0.611
LOC106518511	LOC106514346	A0A2I4BC02	A0A2I4AU54	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	0.447
LOC106518511	LOC106521563	A0A2I4BC02	A0A2I4BPK3	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog.	0.447
LOC106518511	card11	A0A2I4BC02	A0A2I4BKP8	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Caspase recruitment domain-containing protein 11 isoform X1.	0.803
LOC106518511	malt1	A0A2I4BC02	A0A2I4CI63	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1.	0.447
LOC106521563	LOC106514346	A0A2I4BPK3	A0A2I4AU54	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like.	0.906
LOC106521563	LOC106518511	A0A2I4BPK3	A0A2I4BC02	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.447
LOC106521563	card11	A0A2I4BPK3	A0A2I4BKP8	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog.	Caspase recruitment domain-containing protein 11 isoform X1.	0.860
LOC106521563	malt1	A0A2I4BPK3	A0A2I4CI63	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1.	0.903
LOC106521563	prkcd	A0A2I4BPK3	A0A2I4BA02	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.447