(28 nodes) Dynein complex binding network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	LOC106516018	Protein bicaudal D homolog 2-like. (807 aa)
	LOC106510960	Nuclear mitotic apparatus protein 1-like. (669 aa)
	LOC106511993	Nucleoprotein TPR-like isoform X1. (313 aa)
	cenpf	Centromere protein F isoform X1. (2749 aa)
	atmin	ATM interactor. (795 aa)
	ppp1r42	Protein phosphatase 1 regulatory subunit 42. (313 aa)
	dctn6	Dynactin subunit 6. (188 aa)
	pafah1b1	Platelet-activating factor acetylhydrolase IB subunit alpha. (345 aa)
	LOC106515759	Centromere protein F-like isoform X1. (1572 aa)
	tpr	Nucleoprotein TPR. (1975 aa)
	LOC106516822	Nucleoprotein TPR-like. (369 aa)
	numa1	Nuclear mitotic apparatus protein 1 isoform X1. (1091 aa)
	LOC106519330	Protein bicaudal D homolog 2-like. (884 aa)
	smc3	Structural maintenance of chromosomes protein. (1217 aa)
	LOC106523468	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
	LOC106524922	Nucleoprotein TPR-like isoform X1. (2502 aa)
	gpsm2	G-protein-signaling modulator 2 isoform X1. (661 aa)
	LOC106527434	Fragile X mental retardation protein 1 homolog. (414 aa)
	LOC106528256	G-protein-signaling modulator 2-like. (684 aa)
	LOC106529942	Protein bicaudal D homolog 2-like. (862 aa)
	LOC106530154	Protein Hook homolog 2-like. (753 aa)
	LOC106531915	G-protein-signaling modulator 2-like. (684 aa)
	LOC106532179	Protein bicaudal D homolog 1-like. (441 aa)
	LOC106534455	Coiled-coil domain-containing protein 37-like. (391 aa)
	LOC106535182	Protein bicaudal D homolog 1-like. (782 aa)
	LOC106536374	Fragile X mental retardation protein 1 homolog B-like. (621 aa)
	LOC106536392	Coiled-coil domain-containing protein 37-like. (403 aa)
	LOC106537199	Protein bicaudal D homolog 1-like. (925 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106510960	LOC106528256	A0A2I4AI32	A0A2I4CFR9	Nuclear mitotic apparatus protein 1-like.	G-protein-signaling modulator 2-like.	0.812
LOC106510960	LOC106531915	A0A2I4AI32	A0A2I4CTL2	Nuclear mitotic apparatus protein 1-like.	G-protein-signaling modulator 2-like.	0.812
LOC106510960	gpsm2	A0A2I4AI32	A0A2I4CAN9	Nuclear mitotic apparatus protein 1-like.	G-protein-signaling modulator 2 isoform X1.	0.946
LOC106511993	LOC106516822	A0A2I4AKW9	A0A2I4B513	Nucleoprotein TPR-like isoform X1.	Nucleoprotein TPR-like.	0.854
LOC106516018	LOC106523468	A0A2I4B1I1	A0A2I4BX67	Protein bicaudal D homolog 2-like.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	0.508
LOC106516018	dctn6	A0A2I4B1I1	A0A2I4AXT2	Protein bicaudal D homolog 2-like.	Dynactin subunit 6.	0.454
LOC106516018	pafah1b1	A0A2I4B1I1	A0A2I4AZ45	Protein bicaudal D homolog 2-like.	Platelet-activating factor acetylhydrolase IB subunit alpha.	0.508
LOC106516822	LOC106511993	A0A2I4B513	A0A2I4AKW9	Nucleoprotein TPR-like.	Nucleoprotein TPR-like isoform X1.	0.854
LOC106516822	tpr	A0A2I4B513	A0A2I4B4Y8	Nucleoprotein TPR-like.	Nucleoprotein TPR.	0.913
LOC106519330	LOC106523468	A0A2I4BFA8	A0A2I4BX67	Protein bicaudal D homolog 2-like.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	0.508
LOC106519330	dctn6	A0A2I4BFA8	A0A2I4AXT2	Protein bicaudal D homolog 2-like.	Dynactin subunit 6.	0.454
LOC106519330	pafah1b1	A0A2I4BFA8	A0A2I4AZ45	Protein bicaudal D homolog 2-like.	Platelet-activating factor acetylhydrolase IB subunit alpha.	0.508
LOC106523468	LOC106516018	A0A2I4BX67	A0A2I4B1I1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Protein bicaudal D homolog 2-like.	0.508
LOC106523468	LOC106519330	A0A2I4BX67	A0A2I4BFA8	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Protein bicaudal D homolog 2-like.	0.508
LOC106523468	LOC106529942	A0A2I4BX67	A0A2I4CLS1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Protein bicaudal D homolog 2-like.	0.508
LOC106523468	LOC106532179	A0A2I4BX67	A0A2I4CUI8	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Protein bicaudal D homolog 1-like.	0.508
LOC106523468	LOC106535182	A0A2I4BX67	A0A2I4D5R6	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Protein bicaudal D homolog 1-like.	0.508
LOC106523468	LOC106537199	A0A2I4BX67	A0A2I4DCR5	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Protein bicaudal D homolog 1-like.	0.508
LOC106523468	dctn6	A0A2I4BX67	A0A2I4AXT2	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Dynactin subunit 6.	0.611
LOC106523468	pafah1b1	A0A2I4BX67	A0A2I4AZ45	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Platelet-activating factor acetylhydrolase IB subunit alpha.	0.900