STRINGSTRING
pdgfc pdgfc LOC106513237 LOC106513237 LOC106514408 LOC106514408 gdnf gdnf LOC106514811 LOC106514811 fgf23 fgf23 rnf126 rnf126 fgf22 fgf22 adam17 adam17 pdcl3 pdcl3 nptn nptn glmn glmn fgf20 fgf20 LOC106528328 LOC106528328 LOC106527443 LOC106527443 tlr5 tlr5 LOC106526845 LOC106526845 LOC106526827 LOC106526827 LOC106526643 LOC106526643 fgf19 fgf19 fgf4 fgf4 fgf3 fgf3 irak4 irak4 LOC106516544 LOC106516544 LOC106525890 LOC106525890 LOC106525101 LOC106525101 LOC106524062 LOC106524062 LOC106523980 LOC106523980 LOC106523871 LOC106523871 LOC106523548 LOC106523548 LOC106523408 LOC106523408 fam83b fam83b LOC106522509 LOC106522509 LOC106522503 LOC106522503 grem1 grem1 LOC106521899 LOC106521899 LOC106521553 LOC106521553 pdgfd pdgfd pgf pgf ncstn ncstn LOC106520498 LOC106520498 LOC106520132 LOC106520132 vegfa vegfa LOC106519974 LOC106519974 ereg ereg LOC106519868 LOC106519868 LOC106519652 LOC106519652 LOC106518787 LOC106518787 pdgfa pdgfa fgf16 fgf16 LOC106517425 LOC106517425 LOC106516883 LOC106516883 LOC106516533 LOC106516533 LOC106537311 LOC106537311 fgf6 fgf6 LOC106536182 LOC106536182 LOC106536183 LOC106536183 LOC106534548 LOC106534548 fgf1 fgf1 LOC106533727 LOC106533727 src src atxn2 atxn2 snx2 snx2 LOC106533273 LOC106533273 ecm1 ecm1 LOC106532969 LOC106532969 LOC106532847 LOC106532847 LOC106531424 LOC106531424 LOC106531016 LOC106531016 LOC106531189 LOC106531189 LOC106530826 LOC106530826 tgfa tgfa frs3 frs3 LOC106516002 LOC106516002 flrt3 flrt3 vegfb vegfb LOC106515330 LOC106515330 LOC106516236 LOC106516236 esm1 esm1 il1b il1b LOC106511033 LOC106511033 LOC106511175 LOC106511175 LOC106511287 LOC106511287 il1rap il1rap LOC106512030 LOC106512030 pibf1 pibf1 snx1 snx1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pdgfcPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (341 aa)
LOC106513237Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2. (613 aa)
LOC106514408Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (363 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (237 aa)
LOC106514811Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (254 aa)
rnf126E3 ubiquitin-protein ligase RNF126. (317 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
adam17Disintegrin and metalloproteinase domain-containing protein 17. (842 aa)
pdcl3Phosducin-like protein 3. (236 aa)
nptnNeuroplastin isoform X1. (394 aa)
glmnGlomulin. (596 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC106528328Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
LOC106527443Sorting nexin-4-like. (449 aa)
tlr5Toll-like receptor 5; Belongs to the Toll-like receptor family. (880 aa)
LOC106526845Neuroplastin-like isoform X1. (393 aa)
LOC106526827Cysteine-rich motor neuron 1 protein-like. (223 aa)
LOC106526643E3 ubiquitin-protein ligase RNF126-like isoform X1. (313 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
irak4Interleukin-1 receptor-associated kinase 4. (447 aa)
LOC106516544Uncharacterized protein LOC106516544 isoform X1; Belongs to the PDGF/VEGF growth factor family. (497 aa)
LOC106525890Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC106525101Persephin-like. (137 aa)
LOC106524062Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. (602 aa)
LOC106523980Cadherin-5-like isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (795 aa)
LOC106523871Growth factor receptor-bound protein 2. (217 aa)
LOC106523548Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B. (623 aa)
LOC106523408Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (177 aa)
fam83bProtein FAM83B. (928 aa)
LOC106522509Platelet-derived growth factor subunit A-like; Belongs to the PDGF/VEGF growth factor family. (197 aa)
LOC106522503Uncharacterized protein LOC106522503 isoform X1; Belongs to the PDGF/VEGF growth factor family. (543 aa)
grem1Gremlin-1. (174 aa)
LOC106521899Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
LOC106521553Disintegrin and metalloproteinase domain-containing protein 17-like. (856 aa)
pdgfdPlatelet-derived growth factor D. (522 aa)
pgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (163 aa)
ncstnNicastrin isoform X1. (701 aa)
LOC106520498Uncharacterized protein LOC106520498. (209 aa)
LOC106520132Gremlin. (182 aa)
vegfaVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (227 aa)
LOC106519974Leucine-rich repeat transmembrane protein FLRT2-like. (658 aa)
eregProepiregulin. (154 aa)
LOC106519868Pro-neuregulin-4, membrane-bound isoform-like. (158 aa)
LOC106519652GRB2-related adapter protein-like. (247 aa)
LOC106518787Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
pdgfaPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (210 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
LOC106517425Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (178 aa)
LOC106516883Neurturin-like. (226 aa)
LOC106516533GRB2-related adapter protein-like. (222 aa)
LOC106537311Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (91 aa)
fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
LOC106536182Interleukin-1 receptor accessory protein-like. (722 aa)
LOC106536183Interleukin-1 receptor accessory protein-like. (219 aa)
LOC106534548Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
LOC106533727Sorting nexin-1-like. (768 aa)
srcTyrosine-protein kinase. (550 aa)
atxn2Ataxin-2 isoform X1. (1152 aa)
snx2Sorting nexin-2. (545 aa)
LOC106533273Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
ecm1Extracellular matrix protein 1. (495 aa)
LOC106532969Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
LOC106532847Toll-like receptor 5. (654 aa)
LOC106531424Glial cell line-derived neurotrophic factor-like. (309 aa)
LOC106531016Fibroblast growth factor receptor substrate 2-like. (524 aa)
LOC106531189Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. (615 aa)
LOC106530826Sorting nexin-4-like. (438 aa)
tgfaProtransforming growth factor alpha. (242 aa)
frs3Fibroblast growth factor receptor substrate 3. (611 aa)
LOC106516002Proheparin-binding EGF-like growth factor. (229 aa)
flrt3Leucine-rich repeat transmembrane protein FLRT3. (650 aa)
vegfbVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (266 aa)
LOC106515330Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC106516236Probetacellulin-like. (191 aa)
esm1Endothelial cell-specific molecule 1. (200 aa)
il1bInterleukin-1. (246 aa)
LOC106511033Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
LOC106511175Leucine-rich repeat transmembrane protein FLRT2-like. (659 aa)
LOC106511287Fibroblast growth factor 18-like isoform X1; Belongs to the heparin-binding growth factors family. (210 aa)
il1rapInterleukin-1 receptor accessory protein. (429 aa)
LOC106512030Proto-oncogene tyrosine-protein kinase Src-like. (251 aa)
pibf1Progesterone-induced-blocking factor 1. (765 aa)
snx1Sorting nexin-1. (514 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.