STRINGSTRING
cnot2 cnot2 cirbp cirbp zfp36l2 zfp36l2 ythdf2 ythdf2 LOC106536019 LOC106536019 LOC106536002 LOC106536002 LOC106535900 LOC106535900 LOC106535881 LOC106535881 LOC106535332 LOC106535332 parn parn LOC106534985 LOC106534985 LOC106534944 LOC106534944 LOC106534939 LOC106534939 sf3b4 sf3b4 samd4a samd4a LOC106533450 LOC106533450 ttc5 ttc5 mettl3 mettl3 exosc3 exosc3 dcps dcps LOC106532634 LOC106532634 LOC106532230 LOC106532230 LOC106532229 LOC106532229 LOC106532103 LOC106532103 LOC106532104 LOC106532104 nudt21 nudt21 LOC106530231 LOC106530231 LOC106530103 LOC106530103 patl1 patl1 LOC106529673 LOC106529673 exosc5 exosc5 LOC106529426 LOC106529426 LOC106528860 LOC106528860 cnot1 cnot1 LOC106528619 LOC106528619 hrsp12 hrsp12 LOC106527726 LOC106527726 cdc73 cdc73 LOC106526625 LOC106526625 gtpbp1 gtpbp1 zfp36l1 zfp36l1 snw1 snw1 pde12 pde12 noct noct exosc9 exosc9 LOC106524402 LOC106524402 celf4 celf4 ythdf1 ythdf1 tra2b tra2b pan2 pan2 exosc2 exosc2 plekhn1 plekhn1 LOC106522478 LOC106522478 cnot6l cnot6l LOC106521380 LOC106521380 cnot3 cnot3 samd4b samd4b zcchc11 zcchc11 dicer1 dicer1 zcchc6 zcchc6 dhx36 dhx36 LOC106518464 LOC106518464 LOC106517771 LOC106517771 LOC106517664 LOC106517664 cnot6 cnot6 prpf19 prpf19 fto fto mettl14 mettl14 dazap1 dazap1 lsm1 lsm1 tnrc6a tnrc6a polr2g polr2g eif4enif1 eif4enif1 LOC106515813 LOC106515813 LOC106515708 LOC106515708 LOC106510838 LOC106510838 LOC106511070 LOC106511070 LOC106511350 LOC106511350 LOC106511359 LOC106511359 LOC106511585 LOC106511585 LOC106511698 LOC106511698 LOC106511762 LOC106511762 LOC106511761 LOC106511761 LOC106511756 LOC106511756 LOC106511832 LOC106511832 LOC106512371 LOC106512371 LOC106512517 LOC106512517 LOC106512572 LOC106512572 LOC106512772 LOC106512772 cpeb1 cpeb1 dcp1a dcp1a LOC106513399 LOC106513399 pan3 pan3 ythdf3 ythdf3 LOC106513504 LOC106513504 dcp2 dcp2 dis3l2 dis3l2 exosc8 exosc8 LOC106514548 LOC106514548 cnot8 cnot8 LOC106515087 LOC106515087 rbmx rbmx dcp1b dcp1b LOC106515268 LOC106515268 pnpt1 pnpt1 mettl16 mettl16 mlh1 mlh1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cnot2CCR4-NOT transcription complex subunit 2. (521 aa)
cirbpCold-inducible RNA-binding protein. (180 aa)
zfp36l2Zinc finger protein 36, C3H1 type-like 2. (421 aa)
ythdf2YTH domain-containing family protein 2. (639 aa)
LOC106536019CUGBP Elav-like family member 3. (458 aa)
LOC106536002Ribonuclease ZC3H12A-like. (422 aa)
LOC106535900Trinucleotide repeat-containing gene 6C protein-like isoform X1. (1894 aa)
LOC106535881Exosome complex component RRP45-like. (78 aa)
LOC106535332Terminal uridylyltransferase 4-like. (979 aa)
parnpoly(A)-specific ribonuclease PARN isoform X1. (682 aa)
LOC106534985CUGBP Elav-like family member 4. (484 aa)
LOC106534944CCR4-NOT transcription complex subunit 2-like. (529 aa)
LOC106534939Roquin-1-like isoform X1. (1122 aa)
sf3b4Splicing factor 3B subunit 4. (385 aa)
samd4aLOW QUALITY PROTEIN: protein Smaug homolog 1. (719 aa)
LOC106533450Trinucleotide repeat-containing gene 6B protein-like. (2017 aa)
ttc5Tetratricopeptide repeat protein 5. (444 aa)
mettl3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (586 aa)
exosc3Exosome complex component RRP40. (273 aa)
dcpsm7GpppX diphosphatase. (321 aa)
LOC106532634DNA-directed RNA polymerase II subunit RPB4. (143 aa)
LOC106532230Protein argonaute-1. (585 aa)
LOC106532229Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
LOC106532103Nuclear pore complex protein Nup98-Nup96-like. (1631 aa)
LOC106532104Nuclear pore complex protein Nup98-Nup96-like. (90 aa)
nudt21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (234 aa)
LOC106530231Trinucleotide repeat-containing gene 6B protein-like. (2103 aa)
LOC106530103Protein argonaute-3-like; Belongs to the argonaute family. (861 aa)
patl1Protein PAT1 homolog 1. (783 aa)
LOC106529673Zinc finger protein 36, C3H1 type-like 1. (410 aa)
exosc5Exosome complex component RRP46. (218 aa)
LOC106529426CCR4-NOT transcription complex subunit 3-like. (910 aa)
LOC106528860CCR4-NOT transcription complex subunit 7. (286 aa)
cnot1CCR4-NOT transcription complex subunit 1. (2391 aa)
LOC106528619Nucleolin-like. (428 aa)
hrsp12Ribonuclease UK114. (136 aa)
LOC106527726YTH domain-containing family protein 1-like. (607 aa)
cdc73Parafibromin. (530 aa)
LOC106526625Ribonuclease ZC3H12A-like. (593 aa)
gtpbp1GTP-binding protein 1 isoform X1. (681 aa)
zfp36l1Zinc finger protein 36, C3H1 type-like 1 isoform X1. (365 aa)
snw1SNW domain-containing protein 1 isoform X1. (537 aa)
pde122',5'-phosphodiesterase 12. (591 aa)
noctNocturnin isoform X1. (390 aa)
exosc9Exosome complex component RRP45. (424 aa)
LOC106524402Putative helicase mov-10-B.2. (1011 aa)
celf4CUGBP Elav-like family member 4 isoform X1. (266 aa)
ythdf1YTH domain-containing family protein 1 isoform X1. (615 aa)
tra2bTransformer-2 protein homolog beta. (297 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1208 aa)
exosc2Exosome complex component RRP4. (294 aa)
plekhn1Pleckstrin homology domain-containing family N member 1 isoform X1. (719 aa)
LOC106522478GTP-binding protein 1-like. (387 aa)
cnot6lCCR4-NOT transcription complex subunit 6-like. (553 aa)
LOC106521380Protein PAT1 homolog 2-like. (709 aa)
cnot3CCR4-NOT transcription complex subunit 3 isoform X1. (905 aa)
samd4bProtein Smaug homolog 2 isoform X1. (671 aa)
zcchc11Terminal uridylyltransferase 4 isoform X1. (1449 aa)
dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1846 aa)
zcchc6Terminal uridylyltransferase 7 isoform X1. (1306 aa)
dhx36ATP-dependent RNA helicase DHX36. (1071 aa)
LOC106518464Transformer-2 protein homolog alpha-like. (292 aa)
LOC106517771RNA-binding protein 24-like. (120 aa)
LOC106517664Putative helicase mov-10-B.1. (999 aa)
cnot6CCR4-NOT transcription complex subunit 6. (558 aa)
prpf19pre-mRNA-processing factor 19. (505 aa)
ftoAlpha-ketoglutarate-dependent dioxygenase FTO isoform X1. (658 aa)
mettl14N6-adenosine-methyltransferase subunit METTL14; Belongs to the MT-A70-like family. (455 aa)
dazap1DAZ-associated protein 1 isoform X4. (435 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
tnrc6aTrinucleotide repeat-containing gene 6A protein. (1844 aa)
polr2gDNA-directed RNA polymerase II subunit RPB7. (172 aa)
eif4enif1Eukaryotic translation initiation factor 4E transporter isoform X1. (926 aa)
LOC106515813RNA-binding protein 24. (232 aa)
LOC106515708Ribonuclease UK114-like. (135 aa)
LOC106510838Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (868 aa)
LOC106511070Tristetraprolin-like. (424 aa)
LOC106511350Nuclear pore complex protein Nup98-Nup96-like. (951 aa)
LOC106511359Nocturnin-like. (358 aa)
LOC106511585Nocturnin-like. (427 aa)
LOC106511698CCR4-NOT transcription complex subunit 2-like. (145 aa)
LOC106511762Nuclear pore complex protein Nup98-Nup96-like. (208 aa)
LOC106511761Nuclear pore complex protein Nup98-Nup96-like. (318 aa)
LOC106511756Nuclear pore complex protein Nup98-Nup96-like. (212 aa)
LOC106511832DNA mismatch repair protein Mlh1-like. (214 aa)
LOC106512371Protein argonaute-3-like. (384 aa)
LOC106512517GTP-binding protein 1-like. (316 aa)
LOC106512572Exosome complex component RRP42-like. (291 aa)
LOC106512772DNA-directed RNA polymerase II subunit RPB4-like. (139 aa)
cpeb1Cytoplasmic polyadenylation element-binding protein 1 isoform X1. (581 aa)
dcp1amRNA-decapping enzyme 1A. (490 aa)
LOC106513399Nanos homolog 2-like; Belongs to the nanos family. (150 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (786 aa)
ythdf3YTH domain-containing family protein 3. (604 aa)
LOC106513504Putative helicase mov-10-B.1. (396 aa)
dcp2m7GpppN-mRNA hydrolase isoform X1. (396 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1058 aa)
exosc8Exosome complex component RRP43. (277 aa)
LOC106514548Roquin-2-like isoform X1. (1154 aa)
cnot8LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 8. (285 aa)
LOC106515087CUGBP Elav-like family member 3 isoform X1. (483 aa)
rbmxRNA-binding motif protein, X chromosome. (386 aa)
dcp1bmRNA-decapping enzyme 1B. (668 aa)
LOC106515268Trinucleotide repeat-containing gene 6C protein-like isoform X1. (1883 aa)
pnpt1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (770 aa)
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (545 aa)
mlh1DNA mismatch repair protein Mlh1 isoform X1. (743 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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