(16 nodes) Beta-catenin destruction complex network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106522717	Axin-1-like. (882 aa)
	ctnnbip1	Beta-catenin-interacting protein 1. (81 aa)
	apc2	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2. (2517 aa)
	LOC106519965	Ankyrin repeat domain-containing protein 6-like isoform X1. (505 aa)
	LOC106535880	Adenomatous polyposis coli protein-like. (1147 aa)
	ankrd6	Ankyrin repeat domain-containing protein 6. (745 aa)
	LOC106518754	Axin-2-like isoform X1. (839 aa)
	LOC106519557	Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily. (438 aa)
	LOC106535279	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (421 aa)
	LOC106511172	Glycogen synthase kinase-3 beta-like. (128 aa)
	LOC106537373	Adenomatous polyposis coli protein-like. (1835 aa)
	LOC106524605	Axin-2-like. (786 aa)
	axin1	Axin-1. (846 aa)
	gsk3b	Glycogen synthase kinase-3 beta. (138 aa)
	LOC106532331	Glycogen synthase kinase-3 alpha-like; Belongs to the protein kinase superfamily. (440 aa)
	cacybp	Calcyclin-binding protein. (227 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106511172	LOC106518754	A0A2I4AIR5	A0A2I4BCZ7	Glycogen synthase kinase-3 beta-like.	Axin-2-like isoform X1.	0.740
LOC106511172	LOC106522717	A0A2I4AIR5	A0A2I4BUB0	Glycogen synthase kinase-3 beta-like.	Axin-1-like.	0.756
LOC106511172	LOC106524605	A0A2I4AIR5	A0A2I4C1Q6	Glycogen synthase kinase-3 beta-like.	Axin-2-like.	0.740
LOC106511172	LOC106535880	A0A2I4AIR5	A0A2I4D8B3	Glycogen synthase kinase-3 beta-like.	Adenomatous polyposis coli protein-like.	0.712
LOC106511172	LOC106537373	A0A2I4AIR5	A0A2I4DD68	Glycogen synthase kinase-3 beta-like.	Adenomatous polyposis coli protein-like.	0.712
LOC106511172	apc2	A0A2I4AIR5	A0A2I4BIY7	Glycogen synthase kinase-3 beta-like.	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	0.712
LOC106511172	axin1	A0A2I4AIR5	A0A2I4CGW3	Glycogen synthase kinase-3 beta-like.	Axin-1.	0.756
LOC106518754	LOC106511172	A0A2I4BCZ7	A0A2I4AIR5	Axin-2-like isoform X1.	Glycogen synthase kinase-3 beta-like.	0.740
LOC106518754	LOC106519557	A0A2I4BCZ7	A0A2I4BG58	Axin-2-like isoform X1.	Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily.	0.740
LOC106518754	LOC106532331	A0A2I4BCZ7	A0A2I4CV03	Axin-2-like isoform X1.	Glycogen synthase kinase-3 alpha-like; Belongs to the protein kinase superfamily.	0.740
LOC106518754	LOC106535279	A0A2I4BCZ7	A0A2I4D643	Axin-2-like isoform X1.	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily.	0.975
LOC106518754	LOC106535880	A0A2I4BCZ7	A0A2I4D8B3	Axin-2-like isoform X1.	Adenomatous polyposis coli protein-like.	0.769
LOC106518754	LOC106537373	A0A2I4BCZ7	A0A2I4DD68	Axin-2-like isoform X1.	Adenomatous polyposis coli protein-like.	0.975
LOC106518754	apc2	A0A2I4BCZ7	A0A2I4BIY7	Axin-2-like isoform X1.	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	0.975
LOC106518754	gsk3b	A0A2I4BCZ7	A0A2I4CRH6	Axin-2-like isoform X1.	Glycogen synthase kinase-3 beta.	0.769
LOC106519557	LOC106518754	A0A2I4BG58	A0A2I4BCZ7	Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily.	Axin-2-like isoform X1.	0.740
LOC106519557	LOC106522717	A0A2I4BG58	A0A2I4BUB0	Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily.	Axin-1-like.	0.756
LOC106519557	LOC106524605	A0A2I4BG58	A0A2I4C1Q6	Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily.	Axin-2-like.	0.740
LOC106519557	LOC106535880	A0A2I4BG58	A0A2I4D8B3	Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily.	Adenomatous polyposis coli protein-like.	0.712
LOC106519557	LOC106537373	A0A2I4BG58	A0A2I4DD68	Glycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily.	Adenomatous polyposis coli protein-like.	0.712