(101 nodes) Side of membrane network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106511037	UPF0415 protein C7orf25 homolog isoform X1. (439 aa)
	gnb4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	LOC106512237	Mucin-1-like. (157 aa)
	LOC106512599	Laforin-like. (255 aa)
	LOC106513041	ERBB receptor feedback inhibitor 1-like. (377 aa)
	stac3	SH3 and cysteine-rich domain-containing protein 3. (337 aa)
	bdh1	D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
	zdhhc23	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (422 aa)
	efna5	ephrin-A5; Belongs to the ephrin family. (229 aa)
	errfi1	ERBB receptor feedback inhibitor 1. (426 aa)
	rasa3	Ras GTPase-activating protein 3. (833 aa)
	LOC106514188	C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	LOC106514187	C-C chemokine receptor type 8-like; Belongs to the G-protein coupled receptor 1 family. (340 aa)
	sema7a	semaphorin-7A; Belongs to the semaphorin family. (659 aa)
	sppl3	Signal peptide peptidase-like 3. (383 aa)
	gnaz	Guanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
	LOC106514756	Protein arginine N-methyltransferase 8-B-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (405 aa)
	kras	GTPase KRas isoform X1. (189 aa)
	LOC106516123	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like. (340 aa)
	LOC106516374	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like. (340 aa)
	ptprc	Receptor-type tyrosine-protein phosphatase C. (863 aa)
	sppl2b	Signal peptide peptidase-like 2B isoform X1. (556 aa)
	LOC106516939	Sorting nexin. (622 aa)
	LOC106516984	FERM domain-containing protein 1-like. (382 aa)
	LOC106517266	Folate receptor beta-like. (241 aa)
	LOC106517423	Uncharacterized protein LOC106517423. (1296 aa)
	LOC106517611	Sorting nexin-9-like isoform X1. (529 aa)
	LOC106517635	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
	LOC106517856	Riboflavin-binding protein-like. (277 aa)
	rps26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (129 aa)
	cd34	Hematopoietic progenitor cell antigen CD34 isoform X1. (337 aa)
	igsf21	Immunoglobulin superfamily member 21. (494 aa)
	rps29	40S ribosomal protein S29. (56 aa)
	frmd1	FERM domain-containing protein 1. (583 aa)
	gnb1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	LOC106518959	C-C chemokine receptor type 6-like; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	sppl2a	Signal peptide peptidase-like 2A isoform X1. (537 aa)
	LOC106518983	Guanine nucleotide-binding protein subunit beta-5-like. (395 aa)
	rtn4r	Reticulon-4 receptor. (465 aa)
	LOC106519591	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3-like. (342 aa)
	LOC106519638	Cell death-inducing p53-target protein 1-like isoform X1. (196 aa)
	LOC106519673	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog. (179 aa)
	epm2a	Laforin. (316 aa)
	LOC106520346	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	LOC106520401	Cell death-inducing p53-target protein 1 homolog. (135 aa)
	LOC106521057	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3-like. (340 aa)
	gnb5	Guanine nucleotide-binding protein subunit beta-5. (361 aa)
	LOC106521554	Guanine nucleotide-binding protein subunit alpha-11-like. (369 aa)
	LOC106521600	Metastasis suppressor protein 1-like. (84 aa)
	LOC106521674	Thyroid adenoma-associated protein homolog isoform X1. (1862 aa)
	LOC106522242	MTSS1-like protein. (773 aa)
	LOC106522243	MTSS1-like protein. (115 aa)
	LOC106522518	semaphorin-7A-like; Belongs to the semaphorin family. (550 aa)
	LOC106522599	Teratocarcinoma-derived growth factor-like. (198 aa)
	rgs2	Regulator of G-protein signaling 2. (202 aa)
	LOC106524060	semaphorin-7A-like isoform X1; Belongs to the semaphorin family. (641 aa)
	rasa2	Ras GTPase-activating protein 2. (832 aa)
	wnt2b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
	LOC106525982	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	lrrk2	Leucine-rich repeat serine/threonine-protein kinase 2. (2528 aa)
	LOC106526369	Protein arginine N-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (347 aa)
	LOC106526529	Thyroid adenoma-associated protein homolog. (1903 aa)
	LOC106526964	Regulator of G-protein signaling 2-like. (177 aa)
	LOC106527048	Migration and invasion enhancer 1-like. (83 aa)
	apopt1	Apoptogenic protein 1, mitochondrial. (190 aa)
	LOC106527332	Migration and invasion enhancer 1-like. (95 aa)
	LOC106527651	ephrin-A5-like; Belongs to the ephrin family. (229 aa)
	LOC106527773	Uncharacterized protein LOC106527773. (284 aa)
	LOC106528739	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog. (198 aa)
	cdip1	Cell death-inducing p53-target protein 1. (207 aa)
	LOC106529093	LOW QUALITY PROTEIN: MTSS1-like protein. (902 aa)
	borcs5	Loss of heterozygosity 12 chromosomal region 1 protein. (197 aa)
	fes	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (731 aa)
	LOC106530235	Metastasis suppressor protein 1-like. (358 aa)
	LOC106530524	Cyclin-dependent kinase 17. (527 aa)
	serpine2	Glia-derived nexin isoform X1; Belongs to the serpin family. (394 aa)
	LOC106530895	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	rps28	40S ribosomal protein S28. (69 aa)
	LOC106531365	Metastasis suppressor protein 1-like. (842 aa)
	LOC106531784	Myocardial zonula adherens protein-like isoform X1. (687 aa)
	LOC106531792	Cell death-inducing p53-target protein 1 homolog. (175 aa)
	hm13	Minor histocompatibility antigen H13. (391 aa)
	litaf	Lipopolysaccharide-induced tumor necrosis factor-alpha factor. (157 aa)
	LOC106533171	Aquaporin FA-CHIP-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (280 aa)
	LOC106533179	Aquaporin-1-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	LOC106533239	C-C chemokine receptor type 6-like; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	ccr6	C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (388 aa)
	LOC106533964	Cyclin-dependent kinase 17 isoform X1. (527 aa)
	LOC106534245	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog. (153 aa)
	LOC106534498	Ras GTPase-activating protein 3-like. (833 aa)
	fer	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (825 aa)
	syap1	Synapse-associated protein 1. (358 aa)
	mtss1l	MTSS1-like protein isoform X1. (782 aa)
	LOC106535238	Tumor necrosis factor ligand superfamily member 15-like; Belongs to the tumor necrosis factor family. (137 aa)
	LOC106535433	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	LOC106535761	Metastasis suppressor protein 1-like. (753 aa)
	LOC106536232	Tyrosine-protein kinase Fes/Fps-like. (187 aa)
	LOC106536304	Cyclin-dependent kinase 17-like isoform X1. (548 aa)
	frmd6	FERM domain-containing protein 6 isoform X1. (633 aa)
	LOC106536839	Thyroid adenoma-associated protein homolog. (944 aa)
	LOC106537242	Protein arginine N-methyltransferase 8-B; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (334 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106516123	LOC106516984	A0A2I4B221	A0A2I4B5R6	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	FERM domain-containing protein 1-like.	0.495
LOC106516123	LOC106520346	A0A2I4B221	A0A2I4BJB6	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.491
LOC106516123	LOC106521554	A0A2I4B221	A0A2I4BPG4	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Guanine nucleotide-binding protein subunit alpha-11-like.	0.644
LOC106516123	LOC106525982	A0A2I4B221	A0A2I4C773	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.991
LOC106516123	LOC106526964	A0A2I4B221	A0A2I4CAY9	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Regulator of G-protein signaling 2-like.	0.595
LOC106516123	LOC106535433	A0A2I4B221	A0A2I4D6M0	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.779
LOC106516123	frmd6	A0A2I4B221	A0A2I4DB10	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	FERM domain-containing protein 6 isoform X1.	0.495
LOC106516123	gnaz	A0A2I4B221	A0A2I4AUW9	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Guanine nucleotide-binding protein G(Z) subunit alpha.	0.675
LOC106516123	gnb1	A0A2I4B221	A0A2I4BDN4	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.900
LOC106516123	kras	A0A2I4B221	A0A2I4AZR4	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	GTPase KRas isoform X1.	0.718
LOC106516123	rgs2	A0A2I4B221	A0A2I4BWW4	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.	Regulator of G-protein signaling 2.	0.595
LOC106516374	LOC106516984	A0A2I4B312	A0A2I4B5R6	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	FERM domain-containing protein 1-like.	0.495
LOC106516374	LOC106520346	A0A2I4B312	A0A2I4BJB6	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.491
LOC106516374	LOC106521554	A0A2I4B312	A0A2I4BPG4	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	Guanine nucleotide-binding protein subunit alpha-11-like.	0.644
LOC106516374	LOC106525982	A0A2I4B312	A0A2I4C773	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.866
LOC106516374	LOC106526964	A0A2I4B312	A0A2I4CAY9	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	Regulator of G-protein signaling 2-like.	0.595
LOC106516374	LOC106535433	A0A2I4B312	A0A2I4D6M0	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.779
LOC106516374	frmd6	A0A2I4B312	A0A2I4DB10	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	FERM domain-containing protein 6 isoform X1.	0.495
LOC106516374	gnaz	A0A2I4B312	A0A2I4AUW9	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	Guanine nucleotide-binding protein G(Z) subunit alpha.	0.675
LOC106516374	kras	A0A2I4B312	A0A2I4AZR4	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like.	GTPase KRas isoform X1.	0.718