(10 nodes) Adenylate kinase/UMP-CMP kinase network (Austrofundulus limnaeus)

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Your Input:
	ak9	Adenylate kinase 9. (1588 aa)
	ak3	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa)
	ak1	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (193 aa)
	ak4	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (226 aa)
	ak8	Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family. (485 aa)
	ak5	Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family. (565 aa)
	ak7	Adenylate kinase 7. (683 aa)
	cmpk1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (220 aa)
	ak2	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (243 aa)
	LOC106522421	Adenylate kinase 7-like; Belongs to the adenylate kinase family. (559 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106522421	ak1	A0A2I4BSY5	A0A2I4AK33	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	0.956
LOC106522421	ak2	A0A2I4BSY5	A0A2I4CIW6	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	0.919
LOC106522421	ak3	A0A2I4BSY5	A0A2I4AV33	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.407
LOC106522421	ak4	A0A2I4BSY5	A0A2I4AIP3	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.927
LOC106522421	ak5	A0A2I4BSY5	A0A2I4BL68	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family.	0.956
LOC106522421	ak7	A0A2I4BSY5	A0A2I4BHU3	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	Adenylate kinase 7.	0.904
LOC106522421	ak8	A0A2I4BSY5	A0A2I4CE39	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family.	0.963
LOC106522421	ak9	A0A2I4BSY5	A0A2I4BGZ2	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	Adenylate kinase 9.	0.943
LOC106522421	cmpk1	A0A2I4BSY5	A0A2I4CN89	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.502
ak1	LOC106522421	A0A2I4AK33	A0A2I4BSY5	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	0.956
ak1	ak2	A0A2I4AK33	A0A2I4CIW6	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	0.943
ak1	ak3	A0A2I4AK33	A0A2I4AV33	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.549
ak1	ak4	A0A2I4AK33	A0A2I4AIP3	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.935
ak1	ak5	A0A2I4AK33	A0A2I4BL68	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family.	0.900
ak1	ak7	A0A2I4AK33	A0A2I4BHU3	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	Adenylate kinase 7.	0.960
ak1	ak8	A0A2I4AK33	A0A2I4CE39	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family.	0.952
ak1	ak9	A0A2I4AK33	A0A2I4BGZ2	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	Adenylate kinase 9.	0.969
ak2	LOC106522421	A0A2I4CIW6	A0A2I4BSY5	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Adenylate kinase 7-like; Belongs to the adenylate kinase family.	0.919
ak2	ak1	A0A2I4CIW6	A0A2I4AK33	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	0.943
ak2	ak4	A0A2I4CIW6	A0A2I4AIP3	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.920