(32 nodes) Frizzled cysteine-rich domain superfamily network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106523685	Frizzled-3-like isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (734 aa)
	LOC106523846	Secreted frizzled-related protein 5-like. (368 aa)
	fzd6	Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (691 aa)
	fzd9	Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	cpz	Carboxypeptidase Z isoform X1. (661 aa)
	LOC106525940	Frizzled-8-like; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	LOC106526258	Secreted frizzled-related protein 5-like. (282 aa)
	fzd2	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (542 aa)
	fzd3	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (690 aa)
	LOC106529207	Uncharacterized protein LOC106529207. (898 aa)
	LOC106529885	Carboxypeptidase Z-like isoform X1. (670 aa)
	corin	Atrial natriuretic peptide-converting enzyme. (921 aa)
	mfrp	Membrane frizzled-related protein isoform X1. (621 aa)
	LOC106531582	Secreted frizzled-related protein 1-like. (305 aa)
	LOC106531850	frizzled-7-A-like; Belongs to the G-protein coupled receptor Fz/Smo family. (522 aa)
	LOC106533080	Secreted frizzled-related protein 3-like. (310 aa)
	smo	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (813 aa)
	LOC106537208	Secreted frizzled-related protein 5-like. (322 aa)
	LOC106537279	Frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC106519008	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
	ror1	Tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (951 aa)
	fzd4	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
	LOC106517262	Secreted frizzled-related protein 2-like. (343 aa)
	LOC106511782	Atrial natriuretic peptide-converting enzyme-like. (114 aa)
	LOC106512451	Atrial natriuretic peptide-converting enzyme-like. (202 aa)
	musk	Muscle, skeletal receptor tyrosine-protein kinase isoform X1. (962 aa)
	fzd10	Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	fzd8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	LOC106519701	frizzled-7-A-like; Belongs to the G-protein coupled receptor Fz/Smo family. (561 aa)
	ror2	Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
	LOC106522253	Collagen alpha-1(XVIII) chain-like. (1647 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106517262	LOC106519008	A0A2I4B6U4	A0A2I4BDV8	Secreted frizzled-related protein 2-like.	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.689
LOC106517262	LOC106519701	A0A2I4B6U4	A0A2I4BGT5	Secreted frizzled-related protein 2-like.	frizzled-7-A-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.688
LOC106517262	LOC106523685	A0A2I4B6U4	A0A2I4BY42	Secreted frizzled-related protein 2-like.	Frizzled-3-like isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.718
LOC106517262	LOC106525940	A0A2I4B6U4	A0A2I4C725	Secreted frizzled-related protein 2-like.	Frizzled-8-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.676
LOC106517262	LOC106531850	A0A2I4B6U4	A0A2I4CTD0	Secreted frizzled-related protein 2-like.	frizzled-7-A-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.650
LOC106517262	LOC106537279	A0A2I4B6U4	A0A2I4DCZ9	Secreted frizzled-related protein 2-like.	Frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.676
LOC106517262	fzd10	A0A2I4B6U4	A0A2I4B4D4	Secreted frizzled-related protein 2-like.	Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family.	0.650
LOC106517262	fzd2	A0A2I4B6U4	A0A2I4CFH6	Secreted frizzled-related protein 2-like.	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.688
LOC106517262	fzd3	A0A2I4B6U4	A0A2I4CI33	Secreted frizzled-related protein 2-like.	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family.	0.718
LOC106517262	fzd4	A0A2I4B6U4	A0A2I4BP43	Secreted frizzled-related protein 2-like.	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.650
LOC106517262	fzd6	A0A2I4B6U4	A0A2I4BZ19	Secreted frizzled-related protein 2-like.	Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.718
LOC106517262	fzd8	A0A2I4B6U4	A0A2I4BMM6	Secreted frizzled-related protein 2-like.	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.676
LOC106517262	fzd9	A0A2I4B6U4	A0A2I4C0U9	Secreted frizzled-related protein 2-like.	Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family.	0.650
LOC106517262	ror1	A0A2I4B6U4	A0A2I4BPR0	Secreted frizzled-related protein 2-like.	Tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.439
LOC106517262	ror2	A0A2I4B6U4	A0A2I4BS43	Secreted frizzled-related protein 2-like.	Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.439
LOC106519008	LOC106517262	A0A2I4BDV8	A0A2I4B6U4	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2-like.	0.689
LOC106519008	LOC106531582	A0A2I4BDV8	A0A2I4CSH0	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 1-like.	0.688
LOC106519008	LOC106537208	A0A2I4BDV8	A0A2I4DCR9	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5-like.	0.688
LOC106519008	fzd4	A0A2I4BDV8	A0A2I4BP43	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.409
LOC106519008	ror1	A0A2I4BDV8	A0A2I4BPR0	Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.816