(24 nodes) Sm domain network (Austrofundulus limnaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106531753	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	snrpf	Small nuclear ribonucleoprotein F. (86 aa)
	LOC106531024	Protein LSM14 homolog A-like. (491 aa)
	lsm4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (147 aa)
	LOC106525186	Protein LSM14 homolog B-like. (248 aa)
	atxn2	Ataxin-2 isoform X1. (1152 aa)
	lsm10	U7 snRNA-associated Sm-like protein LSm10. (150 aa)
	lsm12	Protein LSM12 homolog. (196 aa)
	lsm14b	Protein LSM14 homolog B isoform X1. (379 aa)
	lsm1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	lsm7	U6 snRNA-associated Sm-like protein LSm7. (103 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	naa38	N(Alpha)-acetyltransferase 38, NatC auxiliary subunit isoform X1. (124 aa)
	lsm5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	lsm11	U7 snRNA-associated Sm-like protein LSm11. (321 aa)
	lsm8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	lsm14a	Protein LSM14 homolog A isoform X1. (444 aa)
	lsm2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	lsm6	U6 snRNA-associated Sm-like protein LSm6. (80 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)

Your Current Organism:

Austrofundulus limnaeus

NCBI taxonomy Id: 52670
Other names: A. limnaeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106525186	lsm1	A0A2I4C468	A0A2I4B4J5	Protein LSM14 homolog B-like.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.463
LOC106531024	lsm1	A0A2I4CQG3	A0A2I4B4J5	Protein LSM14 homolog A-like.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.516
LOC106531753	atxn2	A0A2I4CT11	A0A2I4CZQ0	Small nuclear ribonucleoprotein-associated protein.	Ataxin-2 isoform X1.	0.545
LOC106531753	lsm1	A0A2I4CT11	A0A2I4B4J5	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.441
LOC106531753	lsm10	A0A2I4CT11	A0A2I4D535	Small nuclear ribonucleoprotein-associated protein.	U7 snRNA-associated Sm-like protein LSm10.	0.945
LOC106531753	lsm11	A0A2I4CT11	A0A2I4BR03	Small nuclear ribonucleoprotein-associated protein.	U7 snRNA-associated Sm-like protein LSm11.	0.730
LOC106531753	lsm12	A0A2I4CT11	A0A2I4D6I8	Small nuclear ribonucleoprotein-associated protein.	Protein LSM12 homolog.	0.425
LOC106531753	lsm2	A0A2I4CT11	A0A2I4CCT9	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.930
LOC106531753	lsm3	A0A2I4CT11	A0A2I4CHF1	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.838
LOC106531753	lsm4	A0A2I4CT11	A0A2I4BEU3	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.850
LOC106531753	lsm5	A0A2I4CT11	A0A2I4BSP9	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.845
LOC106531753	lsm6	A0A2I4CT11	A0A2I4CD61	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm6.	0.892
LOC106531753	lsm7	A0A2I4CT11	A0A2I4AKL3	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm7.	0.899
LOC106531753	lsm8	A0A2I4CT11	A0A2I4AIV2	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.925
LOC106531753	snrpd1	A0A2I4CT11	A0A2I4B0I7	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.997
LOC106531753	snrpd2	A0A2I4CT11	A0A2I4BS13	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D2.	0.998
LOC106531753	snrpd3	A0A2I4CT11	A0A2I4AV47	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D3.	0.998
LOC106531753	snrpe	A0A2I4CT11	A0A2I4CGQ5	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.998
LOC106531753	snrpf	A0A2I4CT11	A0A2I4CMT3	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein F.	0.998
LOC106531753	snrpg	A0A2I4CT11	A0A2I4BVL4	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein G.	0.998