STRINGSTRING
psmd2 psmd2 psmc5 psmc5 LOC106521431 LOC106521431 LOC106521574 LOC106521574 pole4 pole4 pole pole LOC106521949 LOC106521949 orc3 orc3 LOC106522128 LOC106522128 LOC106522130 LOC106522130 LOC106522212 LOC106522212 psme2 psme2 mcm2 mcm2 gltscr1 gltscr1 psmd8 psmd8 LOC106523089 LOC106523089 psmd12 psmd12 LOC106523505 LOC106523505 psmd9 psmd9 LOC106524021 LOC106524021 tm7sf3 tm7sf3 pola1 pola1 cdc16 cdc16 psmf1 psmf1 LOC106525086 LOC106525086 LOC106525098 LOC106525098 rpa3 rpa3 meiob meiob LOC106525245 LOC106525245 psmd10 psmd10 mcm7 mcm7 anapc4 anapc4 psma6 psma6 pole2 pole2 psmc1 psmc1 fzr1 fzr1 rpa2 rpa2 psmb3 psmb3 psma3 psma3 LOC106527735 LOC106527735 LOC106527753 LOC106527753 LOC106527799 LOC106527799 LOC106527800 LOC106527800 LOC106519546 LOC106519546 LOC106527833 LOC106527833 kpnb1 kpnb1 psmd3 psmd3 cdc27 cdc27 LOC106528837 LOC106528837 psma2 psma2 mcm8 mcm8 anapc7 anapc7 anapc5 anapc5 LOC106529614 LOC106529614 psmb4 psmb4 psme1 psme1 mcm9 mcm9 cdc7 cdc7 mcm10 mcm10 LOC106530661 LOC106530661 ube2s ube2s psma1 psma1 kpna6 kpna6 mcm3 mcm3 ube2c ube2c anapc10 anapc10 cdc23 cdc23 psmc2 psmc2 LOC106533213 LOC106533213 LOC106533276 LOC106533276 LOC106533547 LOC106533547 mcm4 mcm4 pole3 pole3 LOC106534377 LOC106534377 LOC106534515 LOC106534515 cdc26 cdc26 fam89a fam89a cdc6 cdc6 LOC106534936 LOC106534936 LOC106534943 LOC106534943 orc4 orc4 anapc11 anapc11 anapc2 anapc2 psmc4 psmc4 psme3 psme3 LOC106535907 LOC106535907 LOC106536729 LOC106536729 LOC106519548 LOC106519548 orc1 orc1 LOC106537244 LOC106537244 kxd1 kxd1 prim2 prim2 cdk2 cdk2 LOC106510792 LOC106510792 rps27a rps27a psmd1 psmd1 LOC106511027 LOC106511027 LOC106511290 LOC106511290 LOC106511613 LOC106511613 LOC106511800 LOC106511800 LOC106511864 LOC106511864 LOC106511955 LOC106511955 LOC106512191 LOC106512191 psma4 psma4 LOC106513019 LOC106513019 psmd13 psmd13 psmc3 psmc3 psmb1 psmb1 psma5 psma5 LOC106513356 LOC106513356 kpna1 kpna1 LOC106519545 LOC106519545 cdc45 cdc45 LOC106513800 LOC106513800 cdt1 cdt1 psmd14 psmd14 LOC106514195 LOC106514195 LOC106514299 LOC106514299 orc5 orc5 LOC106514956 LOC106514956 anapc1 anapc1 gmnn gmnn pola2 pola2 psmd5 psmd5 LOC106516344 LOC106516344 anapc16 anapc16 prim1 prim1 LOC106516843 LOC106516843 anapc15 anapc15 mcm5 mcm5 mcm6 mcm6 orc2 orc2 LOC106518112 LOC106518112 psmc6 psmc6 psmd6 psmd6 LOC106518873 LOC106518873 gltscr1l gltscr1l uba52 uba52 psmb8 psmb8 LOC106520301 LOC106520301
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (412 aa)
LOC106521431Histone H2B; Belongs to the histone H2B family. (124 aa)
LOC106521574C-C motif chemokine 20-like. (122 aa)
pole4DNA polymerase epsilon subunit 4 isoform X1. (128 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2287 aa)
LOC10652194926S proteasome non-ATPase regulatory subunit 11B. (422 aa)
orc3Origin recognition complex subunit 3. (720 aa)
LOC106522128Proteasome subunit alpha type. (246 aa)
LOC106522130Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106522212Proteasome subunit beta. (277 aa)
psme2Proteasome activator complex subunit 2. (245 aa)
mcm2DNA helicase; Belongs to the MCM family. (892 aa)
gltscr1Glioma tumor suppressor candidate region gene 1 protein. (1247 aa)
psmd826S proteasome non-ATPase regulatory subunit 8. (265 aa)
LOC106523089Ubiquitin-conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (202 aa)
psmd1226S proteasome non-ATPase regulatory subunit 12. (510 aa)
LOC106523505Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (665 aa)
psmd926S proteasome non-ATPase regulatory subunit 9. (221 aa)
LOC106524021Protein FAM89A-like. (122 aa)
tm7sf3Transmembrane 7 superfamily member 3 isoform X1. (663 aa)
pola1DNA polymerase. (1468 aa)
cdc16Cell division cycle protein 16 homolog isoform X1. (619 aa)
psmf1Proteasome inhibitor PI31 subunit. (277 aa)
LOC106525086Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC106525098Histone H2B; Belongs to the histone H2B family. (124 aa)
rpa3Replication protein A 14 kDa subunit. (122 aa)
meiobMeiosis-specific with OB domain-containing protein. (463 aa)
LOC10652524526S proteasome non-ATPase regulatory subunit 11A. (422 aa)
psmd1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (796 aa)
psma6Proteasome subunit alpha type. (246 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
fzr1Fizzy-related protein homolog. (496 aa)
rpa2Replication protein A 32 kDa subunit. (272 aa)
psmb3Proteasome subunit beta. (205 aa)
psma3Proteasome subunit alpha type. (255 aa)
LOC106527735Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC106527753Histone H2A; Belongs to the histone H2A family. (105 aa)
LOC106527799Histone H3-like; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (250 aa)
LOC106527800Histone H2A; Belongs to the histone H2A family. (142 aa)
LOC106519546Proteasome subunit beta. (275 aa)
LOC106527833Histone H2A; Belongs to the histone H2A family. (146 aa)
kpnb1Importin subunit beta-1. (876 aa)
psmd326S proteasome non-ATPase regulatory subunit 3. (522 aa)
cdc27Cell division cycle protein 27 homolog. (802 aa)
LOC106528837Histone H2A; Belongs to the histone H2A family. (127 aa)
psma2Proteasome subunit alpha type. (234 aa)
mcm8DNA helicase MCM8; Belongs to the MCM family. (686 aa)
anapc7Anaphase-promoting complex subunit 7. (565 aa)
anapc5Anaphase-promoting complex subunit 5. (773 aa)
LOC106529614Fizzy-related protein homolog. (487 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
psme1Proteasome activator complex subunit 1. (250 aa)
mcm9DNA helicase MCM9; Belongs to the MCM family. (516 aa)
cdc7Cell division cycle 7-related protein kinase isoform X1. (554 aa)
mcm10Protein MCM10 homolog isoform X1. (871 aa)
LOC106530661Importin subunit alpha; Belongs to the importin alpha family. (536 aa)
ube2sUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
psma1Proteasome subunit alpha type. (263 aa)
kpna6Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
mcm3DNA helicase; Belongs to the MCM family. (814 aa)
ube2cUbiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
cdc23Cell division cycle protein 23 homolog. (573 aa)
psmc226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
LOC106533213Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (601 aa)
LOC10653327626S proteasome non-ATPase regulatory subunit 4-like. (375 aa)
LOC106533547Histone H2B; Belongs to the histone H2B family. (116 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
pole3DNA polymerase epsilon subunit 3. (150 aa)
LOC106534377LOW QUALITY PROTEIN: histone H2B.3-like; Belongs to the histone H2B family. (66 aa)
LOC106534515Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
cdc26Anaphase-promoting complex subunit CDC26. (138 aa)
fam89aProtein FAM89A. (175 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (585 aa)
LOC106534936Histone H2A; Belongs to the histone H2A family. (142 aa)
LOC106534943Histone H3-like; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (246 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (507 aa)
anapc11Anaphase-promoting complex subunit 11. (84 aa)
anapc2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (826 aa)
psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (417 aa)
psme3Proteasome activator complex subunit 3. (256 aa)
LOC106535907Protein DBF4 homolog A-like. (158 aa)
LOC106536729Glioma tumor suppressor candidate region gene 1 protein-like isoform X1. (1703 aa)
LOC106519548Proteasome subunit beta. (216 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (857 aa)
LOC106537244Importin subunit alpha-6-like. (337 aa)
kxd1kxDL motif-containing protein 1. (181 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (514 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC106510792Histone H2A; Belongs to the histone H2A family. (128 aa)
rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (965 aa)
LOC106511027Proteasome subunit alpha type. (246 aa)
LOC106511290Proteasome subunit beta. (199 aa)
LOC106511613Anaphase-promoting complex subunit 4-like. (93 aa)
LOC106511800Proteasome subunit beta. (233 aa)
LOC106511864DNA helicase MCM9-like. (243 aa)
LOC106511955DNA polymerase alpha catalytic subunit-like. (119 aa)
LOC106512191Cell division cycle protein 27 homolog. (194 aa)
psma4Proteasome subunit alpha type. (261 aa)
LOC106513019Histone H2B 1/2-like; Belongs to the histone H2B family. (111 aa)
psmd1326S proteasome non-ATPase regulatory subunit 13. (378 aa)
psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (427 aa)
psmb1Proteasome subunit beta. (237 aa)
psma5Proteasome subunit alpha type. (241 aa)
LOC106513356Ubiquitin-like. (85 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (539 aa)
LOC106519545Proteasome subunit beta type-6-B like protein. (217 aa)
cdc45Cell division control protein 45 homolog isoform X1. (575 aa)
LOC106513800Proteasome subunit beta. (278 aa)
cdt1DNA replication factor Cdt1 isoform X1. (628 aa)
psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
LOC106514195Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC10651429926S protease regulatory subunit 6B-like. (151 aa)
orc5Origin recognition complex subunit 5. (445 aa)
LOC106514956Proteasome subunit beta. (271 aa)
anapc1Anaphase-promoting complex subunit 1. (1976 aa)
gmnnGeminin isoform X1. (259 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (601 aa)
psmd526S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
LOC106516344Histone H2A; Belongs to the histone H2A family. (142 aa)
anapc16Anaphase-promoting complex subunit 16. (108 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (424 aa)
LOC106516843Anaphase-promoting complex subunit 2-like. (249 aa)
anapc15Anaphase-promoting complex subunit 15 isoform X1. (139 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
mcm6DNA helicase; Belongs to the MCM family. (821 aa)
orc2Origin recognition complex subunit 2. (574 aa)
LOC10651811226S proteasome non-ATPase regulatory subunit 4-like. (382 aa)
psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
LOC106518873Ubiquitin-like. (76 aa)
gltscr1lGLTSCR1-like protein. (790 aa)
uba52ubiquitin-60S ribosomal protein L40. (128 aa)
psmb8Proteasome subunit beta. (273 aa)
LOC10652030126S proteasome non-ATPase regulatory subunit 7. (328 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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