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polr2j polr2j polr2h polr2h ccnh ccnh mllt3 mllt3 polr2c polr2c LOC106532059 LOC106532059 LOC106536142 LOC106536142 cinp cinp LOC106534903 LOC106534903 wdr61 wdr61 cdk7 cdk7 supt5h supt5h polr2b polr2b LOC106533313 LOC106533313 LOC106532634 LOC106532634 polr2e polr2e mnat1 mnat1 gtf2h5 gtf2h5 LOC106511108 LOC106511108 LOC106511433 LOC106511433 LOC106511443 LOC106511443 LOC106512772 LOC106512772 nelfcd nelfcd tceb1 tceb1 ercc3 ercc3 gtf2f2 gtf2f2 ssrp1 ssrp1 ell ell LOC106516227 LOC106516227 polr2g polr2g mllt1 mllt1 tceanc2 tceanc2 polr2k polr2k LOC106519130 LOC106519130 LOC106519707 LOC106519707 paf1 paf1 polr2f polr2f nelfe nelfe gtf2h1 gtf2h1 LOC106521413 LOC106521413 nelfb nelfb polr2i polr2i ercc2 ercc2 fam58a fam58a LOC106523116 LOC106523116 aff4 aff4 supt6h supt6h gtf2h3 gtf2h3 LOC106523822 LOC106523822 LOC106523888 LOC106523888 ncbp2 ncbp2 tcea1 tcea1 polr2a polr2a ccnk ccnk tceanc tceanc gtf2f1 gtf2f1 nelfa nelfa LOC106526453 LOC106526453 eaf1 eaf1 cdc73 cdc73 LOC106527039 LOC106527039 supt16h supt16h ccnt1 ccnt1 supt4h1 supt4h1 LOC106528505 LOC106528505 tceb3 tceb3 LOC106529135 LOC106529135 ccnt2 ccnt2 LOC106529473 LOC106529473 LOC106529518 LOC106529518 LOC106529525 LOC106529525 rtf1 rtf1 LOC106530141 LOC106530141 polr2l polr2l leo1 leo1 gtf2h4 gtf2h4 ctr9 ctr9 ctdp1 ctdp1 ncbp1 ncbp1 cdk9 cdk9 LOC106531760 LOC106531760
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ccnhcyclin-H; Belongs to the cyclin family. (319 aa)
mllt3Protein AF-9. (576 aa)
polr2cDNA-directed RNA polymerase II subunit RPB3. (275 aa)
LOC106532059DNA-directed RNA polymerase II subunit RPB2-like. (367 aa)
LOC106536142Protein IWS1 homolog. (805 aa)
cinpCyclin-dependent kinase 2-interacting protein. (212 aa)
LOC106534903RNA polymerase-associated protein RTF1 homolog. (262 aa)
wdr61WD repeat-containing protein 61. (305 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
supt5hTranscription elongation factor SPT5. (1080 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
LOC106533313DNA-directed RNA polymerase II subunit RPB1-like. (290 aa)
LOC106532634DNA-directed RNA polymerase II subunit RPB4. (143 aa)
polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
gtf2h5General transcription factor IIH subunit 5. (71 aa)
LOC106511108Transcription elongation factor B polypeptide 3-like. (563 aa)
LOC106511433Serine/arginine repetitive matrix protein 1-like. (768 aa)
LOC106511443Zinc transporter ZIP13-like. (382 aa)
LOC106512772DNA-directed RNA polymerase II subunit RPB4-like. (139 aa)
nelfcdNegative elongation factor C/D. (579 aa)
tceb1Transcription elongation factor B polypeptide 1; Belongs to the SKP1 family. (112 aa)
ercc3TFIIH basal transcription factor complex helicase XPB subunit. (783 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (697 aa)
ellRNA polymerase II elongation factor ELL. (621 aa)
LOC106516227AF4/FMR2 family member 1-like isoform X1. (1119 aa)
polr2gDNA-directed RNA polymerase II subunit RPB7. (172 aa)
mllt1Protein ENL. (544 aa)
tceanc2Transcription elongation factor A N-terminal and central domain-containing protein 2. (207 aa)
polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
LOC106519130cyclin-T2-like; Belongs to the cyclin family. (587 aa)
LOC106519707General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (253 aa)
paf1RNA polymerase II-associated factor 1 homolog. (535 aa)
polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
nelfeNegative elongation factor E. (355 aa)
gtf2h1General transcription factor IIH subunit 1. (550 aa)
LOC106521413Transcription elongation factor B polypeptide 2. (119 aa)
nelfbNegative elongation factor B isoform X1. (561 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
ercc2TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (782 aa)
fam58aCyclin-related protein FAM58A; Belongs to the cyclin family. (257 aa)
LOC106523116Transcription elongation factor B polypeptide 3-like. (647 aa)
aff4AF4/FMR2 family member 4. (1143 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1751 aa)
gtf2h3General transcription factor IIH subunit 3 isoform X1. (300 aa)
LOC106523822Uncharacterized protein LOC106523822. (2227 aa)
LOC106523888Flocculation protein FLO11-like. (327 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
tcea1Transcription elongation factor A protein 1 isoform X1. (311 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1910 aa)
ccnkcyclin-K; Belongs to the cyclin family. (541 aa)
tceancTranscription elongation factor A N-terminal and central domain-containing protein. (316 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (530 aa)
nelfaNegative elongation factor A. (550 aa)
LOC106526453Protein transport protein SEC31-like. (333 aa)
eaf1ELL-associated factor 1. (259 aa)
cdc73Parafibromin. (530 aa)
LOC106527039Cyclin-dependent kinase 9-like. (239 aa)
supt16hFACT complex subunit SPT16. (1034 aa)
ccnt1cyclin-T1 isoform X1; Belongs to the cyclin family. (697 aa)
supt4h1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
LOC106528505Transcription elongation factor A protein 2-like. (305 aa)
tceb3Transcription elongation factor B polypeptide 3. (381 aa)
LOC106529135Transcription elongation factor B polypeptide 3-like. (179 aa)
ccnt2cyclin-T2 isoform X1; Belongs to the cyclin family. (714 aa)
LOC106529473Probable assembly chaperone of rpl4. (412 aa)
LOC106529518Perforin-1-like. (588 aa)
LOC106529525Transcription elongation factor B polypeptide 2-like. (119 aa)
rtf1RNA polymerase-associated protein RTF1 homolog. (677 aa)
LOC106530141ELL-associated factor 2-like. (250 aa)
polr2lDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
leo1RNA polymerase-associated protein LEO1. (743 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)
ctr9RNA polymerase-associated protein CTR9 homolog. (1152 aa)
ctdp1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (977 aa)
ncbp1Nuclear cap-binding protein subunit 1. (795 aa)
cdk9LOW QUALITY PROTEIN: cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (393 aa)
LOC106531760General transcription factor IIH subunit. (392 aa)
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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