STRINGSTRING
BN2166_0000150 BN2166_0000150 BN2166_0005150 BN2166_0005150 BN2166_0005200 BN2166_0005200 BN2166_0005250 BN2166_0005250 BN2166_0007500 BN2166_0007500 BN2166_0003640 BN2166_0003640 PIF1 PIF1 BN2166_0002260 BN2166_0002260 BN2166_0015750 BN2166_0015750 BN2166_0007140 BN2166_0007140 BN2166_0004410 BN2166_0004410 BN2166_0010040 BN2166_0010040 BN2166_0019600 BN2166_0019600 BN2166_0011190 BN2166_0011190 BN2166_0009130 BN2166_0009130 BN2166_0009780 BN2166_0009780 BN2166_0012140 BN2166_0012140 BN2166_0008260 BN2166_0008260 BN2166_0012590 BN2166_0012590 BN2166_0011180 BN2166_0011180 BN2166_0023950 BN2166_0023950 BN2166_0011910 BN2166_0011910 BN2166_0015840 BN2166_0015840 BN2166_0014180 BN2166_0014180 BN2166_0025450 BN2166_0025450 BN2166_0016890 BN2166_0016890 BN2166_0026100 BN2166_0026100 BN2166_0016730 BN2166_0016730 BN2166_0027950 BN2166_0027950 BN2166_0020340 BN2166_0020340 BN2166_0004120 BN2166_0004120 BN2166_0004570 BN2166_0004570 BN2166_0018610 BN2166_0018610 BN2166_0006320 BN2166_0006320 BN2166_0008170 BN2166_0008170 BN2166_0035600 BN2166_0035600 BN2166_0010270 BN2166_0010270 BN2166_0025130 BN2166_0025130 BN2166_0011720 BN2166_0011720 BN2166_0026630 BN2166_0026630 BN2166_0039050 BN2166_0039050 BN2166_0028130 BN2166_0028130 BN2166_0028330 BN2166_0028330 BN2166_0028160 BN2166_0028160 BN2166_0015970 BN2166_0015970 BN2166_0017070 BN2166_0017070 BN2166_0042650 BN2166_0042650 BN2166_0035640 BN2166_0035640 BN2166_0032580 BN2166_0032580 BN2166_0037140 BN2166_0037140 BN2166_0037190 BN2166_0037190 BN2166_0037390 BN2166_0037390 BN2166_0045950 BN2166_0045950 BN2166_0038290 BN2166_0038290 BN2166_0035180 BN2166_0035180 BN2166_0039440 BN2166_0039440 BN2166_0036580 BN2166_0036580 BN2166_0036730 BN2166_0036730 BN2166_0037180 BN2166_0037180 BN2166_0036510 BN2166_0036510 BN2166_0023620 BN2166_0023620 BN2166_0038730 BN2166_0038730 BN2166_0050300 BN2166_0050300 BN2166_0038760 BN2166_0038760 BN2166_0026670 BN2166_0026670 BN2166_0026870 BN2166_0026870 BN2166_0027170 BN2166_0027170 BN2166_0052700 BN2166_0052700 BN2166_0053950 BN2166_0053950 BN2166_0043930 BN2166_0043930 BN2166_0044580 BN2166_0044580 BN2166_0047540 BN2166_0047540 BN2166_0044680 BN2166_0044680 BN2166_0031070 BN2166_0031070 BN2166_0044760 BN2166_0044760 BN2166_0031420 BN2166_0031420 BN2166_0049990 BN2166_0049990 BN2166_0050590 BN2166_0050590 BN2166_0033270 BN2166_0033270 BN2166_0050940 BN2166_0050940 BN2166_0051940 BN2166_0051940 BN2166_0046860 BN2166_0046860 BN2166_0052190 BN2166_0052190 BN2166_0035170 BN2166_0035170 BN2166_0047310 BN2166_0047310 BN2166_0052830 BN2166_0052830 BN2166_0052980 BN2166_0052980 BN2166_0053080 BN2166_0053080 BN2166_0054030 BN2166_0054030 BN2166_0052610 BN2166_0052610 BN2166_0064900 BN2166_0064900 BN2166_0059430 BN2166_0059430 BN2166_0069100 BN2166_0069100 BN2166_0058010 BN2166_0058010 BN2166_0060380 BN2166_0060380 BN2166_0045720 BN2166_0045720 BN2166_0058860 BN2166_0058860 BN2166_0064690 BN2166_0064690 BN2166_0046420 BN2166_0046420 BN2166_0065140 BN2166_0065140 BN2166_0047320 BN2166_0047320 BN2166_0062530 BN2166_0062530 BN2166_0049570 BN2166_0049570 BN2166_0074350 BN2166_0074350 BN2166_0064910 BN2166_0064910 BN2166_0054770 BN2166_0054770 BN2166_0057520 BN2166_0057520 BN2166_0074060 BN2166_0074060 BN2166_0074460 BN2166_0074460 BN2166_0064520 BN2166_0064520 BN2166_0064920 BN2166_0064920 BN2166_0065470 BN2166_0065470 BN2166_0068670 BN2166_0068670 BN2166_0069170 BN2166_0069170 BN2166_0070870 BN2166_0070870 BN2166_0072770 BN2166_0072770
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BN2166_0000150DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (599 aa)
BN2166_0005150annotation not available (663 aa)
BN2166_0005200annotation not available (1304 aa)
BN2166_0005250BY PROTMAP: gi|342320736|gb|EGU12675.1| DNA ligase [Rhodotorula glutinis ATCC 204091]. (946 aa)
BN2166_0007500CDC45 family. (736 aa)
BN2166_0003640annotation not available (731 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (681 aa)
BN2166_0002260DNA polymerase. (1555 aa)
BN2166_0015750DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (300 aa)
BN2166_0007140BY PROTMAP: gi|647394924|emb|CDR36159.1| RHTO0S01e15544g1_1 [Rhodosporidium toruloides]. (591 aa)
BN2166_0004410Origin recognition complex (ORC) subunit 5 C-terminus-domain containing protein. (703 aa)
BN2166_0010040DNA helicase; Belongs to the MCM family. (2462 aa)
BN2166_0019600Dfp1/Him1, central region-domain containing protein. (719 aa)
BN2166_0011190DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1245 aa)
BN2166_0009130Restriction endonuclease type II-like protein. (332 aa)
BN2166_0009780BY PROTMAP: gi|342319889|gb|EGU11834.1| Proteophosphoglycan ppg4 [Rhodotorula glutinis ATCC 204091]. (274 aa)
BN2166_0012140DNA polymerase. (1990 aa)
BN2166_0008260annotation not available (433 aa)
BN2166_0012590annotation not available (455 aa)
BN2166_0011180BY PROTMAP: gi|342319958|gb|EGU11903.1| RAD51-like protein 2 ISS [Rhodotorula glutinis ATCC 204091]. (297 aa)
BN2166_0023950DNA helicase; Belongs to the MCM family. (1074 aa)
BN2166_0011910Uncharacterized protein. (686 aa)
BN2166_0015840FGENESH: predicted gene_3.35 protein. (295 aa)
BN2166_0014180annotation not available (1032 aa)
BN2166_0025450Sld5 domain-containing protein. (249 aa)
BN2166_0016890DNA polymerase subunit Cdc27. (418 aa)
BN2166_0026100Putative RFC3-DNA replication factor C, 40 kDa subunit. (357 aa)
BN2166_0016730FGENESH: predicted gene_3.124 protein. (789 aa)
BN2166_0027950annotation not available (813 aa)
BN2166_0020340annotation not available (1209 aa)
BN2166_0004120annotation not available (1050 aa)
BN2166_0004570DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (345 aa)
BN2166_0018610annotation not available (709 aa)
BN2166_0006320Rad51-associated protein Brh2. (1137 aa)
BN2166_0008170Checkpoint protein; Belongs to the HUS1 family. (295 aa)
BN2166_0035600DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1012 aa)
BN2166_0010270FGENESH: predicted gene_2.196 protein. (1656 aa)
BN2166_0025130WD_REPEATS_REGION domain-containing protein. (1955 aa)
BN2166_0011720GINS complex, Psf3 component. (180 aa)
BN2166_0026630annotation not available (351 aa)
BN2166_0039050Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (620 aa)
BN2166_0028130FGENESH: predicted gene_5.358 protein. (325 aa)
BN2166_0028330FGENESH: predicted gene_5.378 protein. (732 aa)
BN2166_0028160Replication factor C subunit 4. (438 aa)
BN2166_0015970DUF1767 domain-containing protein. (430 aa)
BN2166_0017070DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (335 aa)
BN2166_0042650Timeless protein-domain containing protein. (1214 aa)
BN2166_0035640annotation not available (807 aa)
BN2166_0032580Replication factor C subunit 1. (887 aa)
BN2166_0037140Origin recognition complex (ORC) subunit 3 N-terminus-domain containing protein. (725 aa)
BN2166_0037190Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (708 aa)
BN2166_0037390DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1189 aa)
BN2166_0045950Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3051 aa)
BN2166_0038290DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (773 aa)
BN2166_0035180MRC1 domain-containing protein. (1494 aa)
BN2166_0039440annotation not available (268 aa)
BN2166_0036580Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (363 aa)
BN2166_0036730BY PROTMAP: gi|342320560|gb|EGU12500.1| Proteophosphoglycan ppg4 [Rhodotorula glutinis ATCC 204091]. (1448 aa)
BN2166_0037180Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (924 aa)
BN2166_0036510annotation not available (1160 aa)
BN2166_0023620BY PROTMAP: gi|342319821|gb|EGU11767.1| Proteophosphoglycan ppg4 [Rhodotorula glutinis ATCC 204091]. (1641 aa)
BN2166_0038730annotation not available (415 aa)
BN2166_0050300DNA replication origin binding protein. (539 aa)
BN2166_0038760DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (733 aa)
BN2166_0026670FGENESH: predicted gene_5.212 protein. (360 aa)
BN2166_0026870DNA-binding HORMA. (263 aa)
BN2166_0027170SNF2 family N-terminal domain-domain containing protein. (1221 aa)
BN2166_0052700FGENESH: predicted gene_10.107 protein. (1330 aa)
BN2166_0053950DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (585 aa)
BN2166_0043930BY PROTMAP: gi|342321555|gb|EGU13488.1| Hydrophilic protein [Rhodotorula glutinis ATCC 204091]. (370 aa)
BN2166_0044580DNA helicase; Belongs to the MCM family. (939 aa)
BN2166_0047540Uncharacterized protein. (1216 aa)
BN2166_0044680BY PROTMAP: gi|647395342|emb|CDR36677.1| RHTO0S02e05380g1_1 [Rhodosporidium toruloides]. (936 aa)
BN2166_0031070P-loop containing nucleoside triphosphate hydrolase protein. (687 aa)
BN2166_0044760Protein kinase-like domain-containing protein. (671 aa)
BN2166_0031420DNA_MISMATCH_REPAIR_2 domain-containing protein. (1020 aa)
BN2166_0049990DNA polymerase. (1118 aa)
BN2166_0050590BY PROTMAP: gi|647403136|emb|CDR49294.1| RHTO0S25e00650g1_1 [Rhodosporidium toruloides]; Belongs to the PI3/PI4-kinase family. (2634 aa)
BN2166_0033270annotation not available (424 aa)
BN2166_0050940BY PROTMAP: gi|342321259|gb|EGU13193.1| Cdk-related kinase 1 [Rhodotorula glutinis ATCC 204091]. (1267 aa)
BN2166_0051940DNA_pol_B_exo1 domain-containing protein. (224 aa)
BN2166_0046860Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (388 aa)
BN2166_0052190DNA mismatch repair protein MSH2; Component of the post-replicative DNA mismatch repair system (MMR). (986 aa)
BN2166_0035170FGENESH: predicted gene_6.439 protein. (771 aa)
BN2166_0047310Rad9-domain containing protein. (537 aa)
BN2166_0052830DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2246 aa)
BN2166_0052980annotation not available (730 aa)
BN2166_0053080DNA helicase; Belongs to the MCM family. (880 aa)
BN2166_0054030Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (686 aa)
BN2166_0052610annotation not available (1535 aa)
BN2166_0064900Uncharacterized protein. (189 aa)
BN2166_0059430annotation not available (762 aa)
BN2166_0069100Rad17 cell cycle checkpoint protein-domain containing protein. (797 aa)
BN2166_0058010annotation not available (933 aa)
BN2166_0060380BY PROTMAP: gi|472586258|gb|EMS23786.1| 3'-5' exonuclease [Rhodosporidium toruloides NP11]. (335 aa)
BN2166_0045720Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (743 aa)
BN2166_0058860Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (842 aa)
BN2166_0064690BY PROTMAP: gi|342319058|gb|EGU11010.1| putative RAD57 protein [Rhodotorula glutinis ATCC 204091]. (556 aa)
BN2166_0046420Belongs to the RecA family. (319 aa)
BN2166_0065140Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
BN2166_0047320BY PROTMAP: gi|342319987|gb|EGU11932.1| putative Endonuclease [Rhodotorula glutinis ATCC 204091]. (1073 aa)
BN2166_0062530annotation not available (835 aa)
BN2166_0049570annotation not available (921 aa)
BN2166_0074350FGENESH: predicted gene_18.86 protein. (726 aa)
BN2166_0064910FGENESH: predicted gene_14.41 protein. (914 aa)
BN2166_0054770ERCC4 domain-containing protein. (1060 aa)
BN2166_0057520DNA helicase; Belongs to the MCM family. (731 aa)
BN2166_0074060DNA primase; Belongs to the eukaryotic-type primase small subunit family. (452 aa)
BN2166_0074460annotation not available (661 aa)
BN2166_0064520BY PROTMAP: gi|472585507|gb|EMS23058.1| bloom syndrome protein [Rhodosporidium toruloides NP11]. (1529 aa)
BN2166_0064920AAA_23 domain-containing protein. (197 aa)
BN2166_0065470BY PROTMAP: gi|342319021|gb|EGU10973.1| Proteophosphoglycan ppg4 [Rhodotorula glutinis ATCC 204091]. (1208 aa)
BN2166_0068670DNA ligase. (872 aa)
BN2166_0069170FGENESH: predicted gene_15.198 protein. (1428 aa)
BN2166_0070870annotation not available (353 aa)
BN2166_0072770Rad51 domain-containing protein. (361 aa)
Your Current Organism:
Rhodotorula toruloides
NCBI taxonomy Id: 5286
Other names: CBS 6016, IFO 8766, IGC 5615, MUCL 28631, NRRL Y-6987, R. toruloides, Rhodosporidium toruloides, Rhodotorula gracilis, Rhodotorula rubescens, Rhodotorula toruloides (I. Banno) Q.M. Wang, F.Y. Bai, M. Groenew. & Boekhout, 2015
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