STRINGSTRING
BN2166_0002170 BN2166_0002170 BN2166_0053950 BN2166_0053950 BN2166_0029020 BN2166_0029020 BN2166_0052700 BN2166_0052700 BN2166_0026670 BN2166_0026670 BN2166_0050300 BN2166_0050300 BN2166_0038730 BN2166_0038730 BN2166_0037180 BN2166_0037180 BN2166_0040040 BN2166_0040040 BN2166_0039440 BN2166_0039440 BN2166_0038290 BN2166_0038290 BN2166_0037190 BN2166_0037190 BN2166_0037140 BN2166_0037140 BN2166_0032580 BN2166_0032580 BN2166_0018570 BN2166_0018570 BN2166_0030630 BN2166_0030630 BN2166_0028160 BN2166_0028160 BN2166_0039050 BN2166_0039050 BN2166_0011720 BN2166_0011720 BN2166_0024960 BN2166_0024960 BN2166_0024380 BN2166_0024380 BN2166_0022210 BN2166_0022210 BN2166_0024540 BN2166_0024540 BN2166_0024390 BN2166_0024390 BN2166_0020680 BN2166_0020680 BN2166_0019510 BN2166_0019510 BN2166_0018210 BN2166_0018210 BN2166_0017610 BN2166_0017610 BN2166_0018080 BN2166_0018080 BN2166_0027950 BN2166_0027950 BN2166_0016730 BN2166_0016730 BN2166_0026100 BN2166_0026100 BN2166_0016890 BN2166_0016890 BN2166_0025450 BN2166_0025450 BN2166_0014180 BN2166_0014180 BN2166_0015840 BN2166_0015840 BN2166_0011910 BN2166_0011910 BN2166_0023950 BN2166_0023950 BN2166_0012590 BN2166_0012590 BN2166_0010080 BN2166_0010080 BN2166_0009780 BN2166_0009780 BN2166_0019600 BN2166_0019600 BN2166_0008380 BN2166_0008380 BN2166_0010040 BN2166_0010040 BN2166_0008540 BN2166_0008540 BN2166_0008190 BN2166_0008190 BN2166_0004410 BN2166_0004410 BN2166_0015750 BN2166_0015750 BN2166_0002460 BN2166_0002460 BN2166_0002260 BN2166_0002260 BN2166_0005040 BN2166_0005040 BN2166_0003390 BN2166_0003390 BN2166_0007500 BN2166_0007500 BN2166_0005250 BN2166_0005250 BN2166_0002500 BN2166_0002500 BN2166_0000150 BN2166_0000150 BN2166_0009970 BN2166_0009970 BN2166_0048390 BN2166_0048390 BN2166_0075320 BN2166_0075320 BN2166_0042310 BN2166_0042310 BN2166_0044580 BN2166_0044580 BN2166_0045430 BN2166_0045430 BN2166_0031070 BN2166_0031070 BN2166_0044760 BN2166_0044760 BN2166_0031670 BN2166_0031670 BN2166_0049990 BN2166_0049990 BN2166_0033070 BN2166_0033070 BN2166_0051940 BN2166_0051940 BN2166_0046860 BN2166_0046860 BN2166_0047260 BN2166_0047260 BN2166_0061100 BN2166_0061100 BN2166_0052830 BN2166_0052830 BN2166_0053080 BN2166_0053080 BN2166_0052260 BN2166_0052260 BN2166_0066300 BN2166_0066300 BN2166_0062690 BN2166_0062690 BN2166_0065140 BN2166_0065140 BN2166_0065240 BN2166_0065240 BN2166_0062530 BN2166_0062530 BN2166_0074350 BN2166_0074350 BN2166_0070030 BN2166_0070030 BN2166_0070730 BN2166_0070730 BN2166_0074240 BN2166_0074240 BN2166_0057520 BN2166_0057520 BN2166_0072510 BN2166_0072510 BN2166_0074060 BN2166_0074060 BN2166_0074810 BN2166_0074810 BN2166_0075110 BN2166_0075110 BN2166_0068670 BN2166_0068670 BN2166_0074820 BN2166_0074820 BN2166_0075020 BN2166_0075020
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BN2166_0002170DNA replication factor A subunit Ssb3. (108 aa)
BN2166_0053950DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (585 aa)
BN2166_0029020Ubiquitin-related domain-containing protein. (154 aa)
BN2166_0052700FGENESH: predicted gene_10.107 protein. (1330 aa)
BN2166_0026670FGENESH: predicted gene_5.212 protein. (360 aa)
BN2166_0050300DNA replication origin binding protein. (539 aa)
BN2166_0038730annotation not available (415 aa)
BN2166_0037180Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (924 aa)
BN2166_0040040annotation not available (718 aa)
BN2166_0039440annotation not available (268 aa)
BN2166_0038290DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (773 aa)
BN2166_0037190Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (708 aa)
BN2166_0037140Origin recognition complex (ORC) subunit 3 N-terminus-domain containing protein. (725 aa)
BN2166_0032580Replication factor C subunit 1. (887 aa)
BN2166_0018570Uncharacterized protein. (230 aa)
BN2166_0030630Uncharacterized protein. (148 aa)
BN2166_0028160Replication factor C subunit 4. (438 aa)
BN2166_0039050Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (620 aa)
BN2166_0011720GINS complex, Psf3 component. (180 aa)
BN2166_0024960Uncharacterized protein. (735 aa)
BN2166_0024380FGENESH: predicted gene_4.214 protein. (2249 aa)
BN2166_0022210FGENESH: predicted gene_3.672 protein. (781 aa)
BN2166_0024540Importin subunit alpha; Belongs to the importin alpha family. (530 aa)
BN2166_0024390FGENESH: predicted gene_4.215 protein. (2233 aa)
BN2166_0020680FGENESH: predicted gene_3.519 protein. (1459 aa)
BN2166_0019510ANAPC5 domain-containing protein. (680 aa)
BN2166_0018210Histone H2B; Belongs to the histone H2B family. (125 aa)
BN2166_0017610FGENESH: predicted gene_3.212 protein. (1777 aa)
BN2166_0018080Histone H2B; Belongs to the histone H2B family. (138 aa)
BN2166_0027950annotation not available (813 aa)
BN2166_0016730FGENESH: predicted gene_3.124 protein. (789 aa)
BN2166_0026100Putative RFC3-DNA replication factor C, 40 kDa subunit. (357 aa)
BN2166_0016890DNA polymerase subunit Cdc27. (418 aa)
BN2166_0025450Sld5 domain-containing protein. (249 aa)
BN2166_0014180annotation not available (1032 aa)
BN2166_0015840FGENESH: predicted gene_3.35 protein. (295 aa)
BN2166_0011910Uncharacterized protein. (686 aa)
BN2166_0023950DNA helicase; Belongs to the MCM family. (1074 aa)
BN2166_0012590annotation not available (455 aa)
BN2166_0010080Uncharacterized protein. (459 aa)
BN2166_0009780BY PROTMAP: gi|342319889|gb|EGU11834.1| Proteophosphoglycan ppg4 [Rhodotorula glutinis ATCC 204091]. (274 aa)
BN2166_0019600Dfp1/Him1, central region-domain containing protein. (719 aa)
BN2166_0008380Putative DNA polymerase. (210 aa)
BN2166_0010040DNA helicase; Belongs to the MCM family. (2462 aa)
BN2166_0008540FGENESH: predicted gene_2.23 protein. (1833 aa)
BN2166_0008190annotation not available (1088 aa)
BN2166_0004410Origin recognition complex (ORC) subunit 5 C-terminus-domain containing protein. (703 aa)
BN2166_0015750DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (300 aa)
BN2166_0002460BY PROTMAP: gi|814541099|emb|CEQ41539.1| SPOSA6832_03267 [Sporidiobolus salmonicolor]; Belongs to the cyclin family. (517 aa)
BN2166_0002260DNA polymerase. (1555 aa)
BN2166_0005040Uncharacterized protein. (150 aa)
BN2166_0003390annotation not available (153 aa)
BN2166_0007500CDC45 family. (736 aa)
BN2166_0005250BY PROTMAP: gi|342320736|gb|EGU12675.1| DNA ligase [Rhodotorula glutinis ATCC 204091]. (946 aa)
BN2166_0002500BY PROTMAP: gi|342319348|gb|EGU11297.1| Proteophosphoglycan 5 [Rhodotorula glutinis ATCC 204091]. (652 aa)
BN2166_0000150DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (599 aa)
BN2166_0009970Histone H2B; Belongs to the histone H2B family. (144 aa)
BN2166_0048390FGENESH: predicted gene_9.185 protein. (101 aa)
BN2166_0075320FGENESH: predicted gene_29.1 protein. (1456 aa)
BN2166_0042310FGENESH: predicted gene_8.86 protein. (1243 aa)
BN2166_0044580DNA helicase; Belongs to the MCM family. (939 aa)
BN2166_0045430Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (328 aa)
BN2166_0031070P-loop containing nucleoside triphosphate hydrolase protein. (687 aa)
BN2166_0044760Protein kinase-like domain-containing protein. (671 aa)
BN2166_0031670BY PROTMAP: gi|342319608|gb|EGU11555.1| Proteophosphoglycan ppg4 [Rhodotorula glutinis ATCC 204091]. (694 aa)
BN2166_0049990DNA polymerase. (1118 aa)
BN2166_0033070annotation not available (266 aa)
BN2166_0051940DNA_pol_B_exo1 domain-containing protein. (224 aa)
BN2166_0046860Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (388 aa)
BN2166_0047260FGENESH: predicted gene_9.72 protein. (1762 aa)
BN2166_0061100BY PROTMAP: gi|814543146|emb|CEQ39523.1| SPOSA6832_01050 [Sporidiobolus salmonicolor]. (389 aa)
BN2166_0052830DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2246 aa)
BN2166_0053080DNA helicase; Belongs to the MCM family. (880 aa)
BN2166_0052260Belongs to the cyclin family. (651 aa)
BN2166_0066300annotation not available (1334 aa)
BN2166_0062690Importin subunit alpha; Belongs to the importin alpha family. (490 aa)
BN2166_0065140Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
BN2166_0065240Belongs to the cyclin family. (606 aa)
BN2166_0062530annotation not available (835 aa)
BN2166_0074350FGENESH: predicted gene_18.86 protein. (726 aa)
BN2166_0070030annotation not available (1384 aa)
BN2166_0070730FGENESH: predicted gene_16.99 protein. (810 aa)
BN2166_0074240BY PROTMAP: gi|647401048|emb|CDR46990.1| RHTO0S13e04478g1_1 [Rhodosporidium toruloides]; Belongs to the protein kinase superfamily. (294 aa)
BN2166_0057520DNA helicase; Belongs to the MCM family. (731 aa)
BN2166_0072510FGENESH: predicted gene_17.109 protein. (1594 aa)
BN2166_0074060DNA primase; Belongs to the eukaryotic-type primase small subunit family. (452 aa)
BN2166_0074810FGENESH: predicted gene_20.4 protein. (781 aa)
BN2166_0075110FGENESH: predicted gene_25.1 protein. (987 aa)
BN2166_0068670DNA ligase. (872 aa)
BN2166_0074820FGENESH: predicted gene_20.5 protein. (1374 aa)
BN2166_0075020FGENESH: predicted gene_24.1 protein. (390 aa)
Your Current Organism:
Rhodotorula toruloides
NCBI taxonomy Id: 5286
Other names: CBS 6016, IFO 8766, IGC 5615, MUCL 28631, NRRL Y-6987, R. toruloides, Rhodosporidium toruloides, Rhodotorula gracilis, Rhodotorula rubescens, Rhodotorula toruloides (I. Banno) Q.M. Wang, F.Y. Bai, M. Groenew. & Boekhout, 2015
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.