STRINGSTRING
purC purC AEH25546.1 AEH25546.1 purA purA nadE nadE AEH25273.1 AEH25273.1 purD purD purM purM purL purL purQ purQ purS purS queC queC AEH25107.1 AEH25107.1 AEH25072.1 AEH25072.1 gatE gatE gatD gatD AEH24821.1 AEH24821.1 purP purP guaAB guaAB guaAA guaAA AEH24315.1 AEH24315.1 AEH24314.1 AEH24314.1 AEH24264.1 AEH24264.1 AEH23997.1 AEH23997.1 pyrG pyrG tiaS tiaS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (234 aa)
AEH25546.1Glutamine synthetase. (441 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa)
nadENAD synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (261 aa)
AEH25273.15-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl. (380 aa)
purDPhosphoribosylamine--glycine ligase (purD); Belongs to the GARS family. (438 aa)
purMPhosphoribosylaminoimidazole synthetase. (333 aa)
purLPhosphoribosylformylglycinamidine synthase II, purL component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is th [...] (707 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (216 aa)
purSPhosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa)
queCTranscription regulator, putative, ExsB family (ExsB); Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (239 aa)
AEH25107.1Biotin-protein ligase. (254 aa)
AEH25072.1Nicotinate phosphoribosyltransferase. (390 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (629 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (437 aa)
AEH24821.1Bifunctional phosphopantothenoylcysteine. (407 aa)
purP5-aminoimidazole-4-carboxamide-1-beta-D- ribofuranosyl; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (331 aa)
guaABGMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. (307 aa)
guaAAGMP synthase subunit A; Catalyzes the synthesis of GMP from XMP. (188 aa)
AEH24315.15-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl. (310 aa)
AEH24314.1Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (219 aa)
AEH24264.1Dihydropteroate synthase. (272 aa)
AEH23997.1Hypothetical protein. (261 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa)
tiaSNucleic acid-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (435 aa)
Your Current Organism:
Pyrococcus yayanosii
NCBI taxonomy Id: 529709
Other names: P. yayanosii CH1, Pyrococcus sp. CH1, Pyrococcus yayanosii CH1, Pyrococcus yayanosii str. CH1, Pyrococcus yayanosii strain CH1
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