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| | AEH24182.1 | dCMP deaminase. (181 aa) |
| | glmS | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa) |
| | AEH25566.1 | nifS protein. (398 aa) |
| | AEH25564.1 | parB-like nuclease, putative. (242 aa) |
| | nnrD | YjeF-like carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (480 aa) |
| | AEH25546.1 | Glutamine synthetase. (441 aa) |
| | AEH25540.1 | Hypothetical protein. (112 aa) |
| | AEH25532.1 | Nicotinamide-nucleotide adenylyltransferase. (188 aa) |
| | AEH25525.1 | 2-haloalkanoic acid dehalogenase-like hydrolase. (235 aa) |
| | AEH25518.1 | Hypothetical protein. (116 aa) |
| | AEH25511.1 | Competence damage-inducible protein A. (251 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa) |
| | ahcY | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (422 aa) |
| | AEH25501.1 | Cyclase-related protein. (194 aa) |
| | AEH25500.1 | Putative tRNA-binding protein. (229 aa) |
| | glpK | Glycerol kinase (glpK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (493 aa) |
| | gcvPB | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (501 aa) |
| | gcvPA | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (464 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (156 aa) |
| | dtdA | Hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (278 aa) |
| | AEH25436.1 | dTDP-glucose 4,6-dehydratase. (333 aa) |
| | AEH25433.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | AEH25426.1 | UTP-glucose-1-phosphate uridylyltransferase (galU). (286 aa) |
| | AEH25425.1 | NDP-sugar dehydrogenase. (427 aa) |
| | AEH25421.1 | dTDP-D-Fucp3N acetylase. (219 aa) |
| | AEH25409.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (467 aa) |
| | AEH25405.1 | GTP:adenosylcobinamide-phosphate guanylyltransferase. (181 aa) |
| | cobS | Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (229 aa) |
| | AEH25396.1 | L-asparaginase. (328 aa) |
| | AEH25387.1 | cob(I)alamin adenosyltransferase. (175 aa) |
| | AEH25357.1 | methylmalonyl-CoA epimerase. (133 aa) |
| | AEH25355.1 | Purine phosphoribosyltransferase. (215 aa) |
| | AEH25354.1 | Asparagine synthetase A. (270 aa) |
| | AEH25350.1 | Diaminopimelate aminotransferase. (419 aa) |
| | AEH25342.1 | Indolepyruvate oxidoreductase subunit B. (193 aa) |
| | lysS | lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (519 aa) |
| | AEH25329.1 | Translation initiation factor IF-2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (322 aa) |
| | AEH25310.1 | L-fuculose 1-phosphate aldolase (fucA). (187 aa) |
| | nadE | NAD synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (261 aa) |
| | AEH25286.1 | Metallo-beta-lactamase superfamily, putative. (229 aa) |
| | mtnP | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (278 aa) |
| | AEH25275.1 | Hypothetical protein. (298 aa) |
| | AEH25273.1 | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl. (380 aa) |
| | purD | Phosphoribosylamine--glycine ligase (purD); Belongs to the GARS family. (438 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (143 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (429 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase. (333 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II, purL component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is th [...] (707 aa) |
| | AEH25262.1 | Incomplete phosphoenolpyruvate synthetase-related protein. (53 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (216 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa) |
| | pgiA | Glucose-6-phosphate isomerase; Belongs to the archaeal-type GPI family. (189 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (408 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (244 aa) |
| | AEH25245.1 | alanyl-tRNA synthetase. (404 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (213 aa) |
| | atpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (464 aa) |
| | atpA | ATP synthase archaeal, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (587 aa) |
| | atpF | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (102 aa) |
| | atpC | V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (370 aa) |
| | atpE | V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (203 aa) |
| | AEH25223.1 | Hydrolase, HAD superfamily. (230 aa) |
| | AEH25221.1 | Metal dependent hydrolase. (270 aa) |
| | AEH25192.1 | Class II glutamine amidotransferase domain protein. (321 aa) |
| | AEH25168.1 | Histidine triad (HIT) protein (hit). (166 aa) |
| | AEH25162.1 | Putative regulatory protein. (93 aa) |
| | AEH25157.1 | Fructose 1,6-bisphosphate aldolase class 1 (fba). (281 aa) |
| | queC | Transcription regulator, putative, ExsB family (ExsB); Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (239 aa) |
| | AEH25148.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) |
| | AEH25143.1 | Purine phosphoribosyltransferase related protein. (153 aa) |
| | AEH25135.1 | Hypothetical protein. (272 aa) |
| | AEH25131.1 | alanyl-tRNA synthetase-related protein. (213 aa) |
| | cpgS | Cyclic 2,3-diphospoglycerate-synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP. (427 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (628 aa) |
| | AEH25072.1 | Nicotinate phosphoribosyltransferase. (390 aa) |
| | AEH25071.1 | Oxidoreductase, short chain dehydrogenase/reductase family. (265 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (225 aa) |
| | AEH25062.1 | Phosphoserine phosphatase (serB). (206 aa) |
| | AEH25058.1 | Metal-dependent phosphohydrolase. (175 aa) |
| | AEH25054.1 | Hypothetical protein; Belongs to the UPF0107 family. (130 aa) |
| | AEH25053.1 | Hypothetical protein. (406 aa) |
| | guaB | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (912 aa) |
| | hisS | histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (436 aa) |
| | AEH25031.1 | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (395 aa) |
| | AEH25027.1 | 2-amino-3-ketobutyrate coenzyme A ligase. (93 aa) |
| | AEH25006.1 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (178 aa) |
| | AEH24998.1 | HAM1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (184 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (384 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (279 aa) |
| | AEH24986.1 | Glucose-1-phosphate thymidylyltransferase. (419 aa) |
| | AEH24976.1 | Hydrolase. (214 aa) |
| | AEH24973.1 | Putative 6-pyruvoyl tetrahydrobiopterin synthase. (149 aa) |
| | AEH24970.1 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (185 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | AEH24966.1 | Bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase. (253 aa) |
| | AEH24944.1 | Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (278 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (316 aa) |
| | AEH24935.1 | UDP-glucose 4-epimerase (galE). (315 aa) |
| | AEH24887.1 | Alcohol dehydrogenase. (331 aa) |
| | AEH24885.1 | Translation initiation inhibitor, putative. (127 aa) |
| | AEH24884.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (450 aa) |
| | AEH24878.1 | Hydrolase, metallo-beta-lactamase superfamily. (263 aa) |
| | AEH24864.1 | Malic enzyme (malate oxidoreductase) (maeB). (438 aa) |
| | AEH24863.1 | Amidohydrolase family, putative. (404 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (186 aa) |
| | AEH24843.1 | Serine aminotransferase. (383 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (437 aa) |
| | AEH24821.1 | Bifunctional phosphopantothenoylcysteine. (407 aa) |
| | AEH24815.1 | Membrane bound hydrogenase, NiFe-hydrogenase large subunit 2. (429 aa) |
| | AEH24813.1 | Membrane bound hydrogenase, NiFe-hydrogenase small subunit. (172 aa) |
| | AEH24803.1 | 4Fe-4S cluster-binding protein. (51 aa) |
| | AEH24792.1 | Formate hydrogenlyase II subunit H. (271 aa) |
| | AEH24785.1 | 4Fe-4S cluster-binding protein. (82 aa) |
| | AEH24784.1 | Hypothetical formate dehydrogenase, alpha subunit. (711 aa) |
| | AEH24775.1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa) |
| | glkA | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. (462 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa) |
| | pdxT | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa) |
| | purP | 5-aminoimidazole-4-carboxamide-1-beta-D- ribofuranosyl; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (331 aa) |
| | guaAB | GMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. (307 aa) |
| | guaAA | GMP synthase subunit A; Catalyzes the synthesis of GMP from XMP. (188 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (733 aa) |
| | AEH24730.1 | 6-pyruvoyl-tetrahydropterin synthase. (115 aa) |
| | queE | Organic radical activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (253 aa) |
| | cysS | cysteinyl-tRNA synthetase. (476 aa) |
| | AEH24720.1 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. (225 aa) |
| | tdh | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (348 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta. (556 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (500 aa) |
| | ribK | Transcriptional regulator, MarR family; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (212 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (155 aa) |
| | AEH24668.1 | Molybdopterin oxidoreductase, molybdopterin-binding subunit. (638 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (232 aa) |
| | AEH24636.1 | Putative kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (185 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (456 aa) |
| | AEH24622.1 | Adenylyl cyclase, CyaB-type, putative. (176 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (375 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa) |
| | AEH24604.1 | Hydrolase. (226 aa) |
| | AEH24594.1 | Pyridoxal-phosphate dependent enzyme superfamily. (390 aa) |
| | AEH24593.1 | Cystathionine gamma-lyase. (385 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (363 aa) |
| | AEH24554.1 | Pyridoxal-phosphate dependent enzyme superfamily. (389 aa) |
| | AEH24553.1 | Cystathionine gamma-lyase. (387 aa) |
| | thi4-2 | Putative thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (263 aa) |
| | AEH24528.1 | Acetylornithine deacetylase. (350 aa) |
| | AEH24524.1 | Cytochrome-c3 hydrogenase subunit gamma. (292 aa) |
| | AEH24517.1 | ferredoxin-NADP(+) reductase subunit alpha. (289 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (884 aa) |
| | cobD | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (288 aa) |
| | AEH24491.1 | Hypothetical protein; Belongs to the UPF0284 family. (337 aa) |
| | AEH24477.1 | Carbamate kinase; Belongs to the carbamate kinase family. (314 aa) |
| | AEH24472.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa) |
| | gcvT | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (401 aa) |
| | pyrD | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. (298 aa) |
| | AEH24440.1 | Amino acid amidohydrolase. (380 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (151 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic subunit. (308 aa) |
| | AEH24433.1 | Metallo-beta-lactamase superfamily protein. (254 aa) |
| | AEH24424.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (327 aa) |
| | AEH24412.1 | Threonine synthase. (443 aa) |
| | AEH24410.1 | Asparagine synthase. (487 aa) |
| | thyX | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (239 aa) |
| | AEH24396.1 | Indolepyruvate oxidoreductase subunit beta. (202 aa) |
| | AEH24395.1 | Indolepyruvate ferredoxin oxidoreductase, subunit alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (644 aa) |
| | mngB | Mannosyl-3-phosphoglycerate phosphatase; Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG). (243 aa) |
| | AEH24383.1 | Mannosyl-3-phosphoglycerate synthase. (394 aa) |
| | AEH24368.1 | Arginase; Belongs to the arginase family. (243 aa) |
| | AEH24361.1 | Cobalamin adenosyltransferase. (172 aa) |
| | AEH24354.1 | Pyruvate ferredoxin oxidoreductase subunit gamma. (185 aa) |
| | AEH24353.1 | 2-ketoisovalerate ferredoxin oxidoreductase subunit delta. (105 aa) |
| | AEH24352.1 | 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha. (394 aa) |
| | AEH24351.1 | 2-ketoisovalerate ferredoxin oxidoreductase subunit beta. (311 aa) |
| | AEH24350.1 | Pyuvate ferredoxin oxidoreductase subunit delta. (105 aa) |
| | AEH24349.1 | Pyruvate ferredoxin oxidoreductase subunit alpha. (395 aa) |
| | AEH24348.1 | Pyruvate ferredoxin oxidoreductase subunit beta. (331 aa) |
| | AEH24339.1 | Indolepyruvate: ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (615 aa) |
| | AEH24338.1 | Predicted metal-dependent hydrolase with the TIM-barrel fold. (508 aa) |
| | AEH24319.1 | Hypothetical protein. (135 aa) |
| | purO | IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (196 aa) |
| | AEH24315.1 | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl. (310 aa) |
| | AEH24314.1 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (219 aa) |
| | thiC | Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (430 aa) |
| | thi4 | Ribulose-1,5-biphosphate synthetase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (252 aa) |
| | AEH24311.1 | Myo-inositol-1-phosphate synthase. (383 aa) |
| | AEH24302.1 | Hydrolase. (223 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (383 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa) |
| | AEH24274.1 | Methylmalonyl-coadecarboxylase, subunit alpha. (520 aa) |
| | AEH24272.1 | glutaconyl-CoA decarboxylase subunit gamma. (142 aa) |
| | AEH24270.1 | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (315 aa) |
| | AEH24264.1 | Dihydropteroate synthase. (272 aa) |
| | ileS | Isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1067 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (573 aa) |
| | cmk | Cytidylate kinase. (192 aa) |
| | AEH24212.1 | ATP-NAD kinase. (378 aa) |
| | AEH24208.1 | Metal-dependent hydrolase; Belongs to the UPF0173 family. (227 aa) |
| | mptE | Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (232 aa) |
| | pdaD | Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. (158 aa) |
| | glyS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (567 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (285 aa) |
| | AEH24091.1 | 3-octaprenyl-4-hydroxybenzoate decarboxylyase. (420 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (438 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (625 aa) |
| | AEH24191.1 | Nucleotide pyrophosphohydrolase. (95 aa) |
| | AEH24112.1 | Translation initiation factor IF-2B subunit beta; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (356 aa) |
| | AEH24134.1 | Hypothetical protein. (485 aa) |
| | AEH24143.1 | Alchol dehydrogenase. (378 aa) |
| | AEH24150.1 | Pyrazinamidase/nicotinamidase. (181 aa) |
| | AEH24152.1 | Histidine triad protein. (110 aa) |
| | AEH24164.1 | 5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. (269 aa) |
| | AEH24173.1 | AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. (503 aa) |
| | AEH24178.1 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa) |
| | uppS | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (264 aa) |
| | AEH23714.1 | ferredoxin-NADP(+) reductase subunit alpha. (277 aa) |
| | AEH23716.1 | Cytochrome-c3 hydrogenase subunit gamma. (288 aa) |
| | rbcL | Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (421 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (406 aa) |
| | fbp | Thermophile-specific fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (374 aa) |
| | AEH23754.1 | Hypothetical protein; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa) |
| | AEH23755.1 | acetyl-CoA acetyltransferase. (385 aa) |
| | AEH23756.1 | acaC protein. (134 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa) |
| | asnS | asparaginyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (434 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (444 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (234 aa) |
| | thiL | Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (314 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase. (334 aa) |
| | AEH23803.1 | GHMP kinase. (302 aa) |
| | mat | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa) |
| | AEH23811.1 | Cysteine synthase. (273 aa) |
| | AEH23827.1 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (408 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa) |
| | AEH23842.1 | Nucleotidyltransferase. (412 aa) |
| | adkA | Adenylate kinase; Belongs to the archaeal adenylate kinase family. (196 aa) |
| | AEH23884.1 | UDP-glucose 4-epimerase. (317 aa) |
| | AEH23916.1 | Hypothetical protein; Belongs to the UPF0292 family. (131 aa) |
| | tmk | Thymidylate kinase. (205 aa) |
| | AEH23925.1 | Adenine phosphoribosyltransferase. (237 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | AEH23927.1 | 2-haloalkanoic acid dehalogenase-like hydrolase. (239 aa) |
| | AEH23932.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma. (182 aa) |
| | AEH23933.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (281 aa) |
| | AEH23934.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (385 aa) |
| | AEH23935.1 | 2-oxoglutarate synthase subunit KorC. (171 aa) |
| | AEH23936.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (283 aa) |
| | AEH23937.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (396 aa) |
| | pfkC | ADP-specific phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (457 aa) |
| | AEH23957.1 | Enolase. (341 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (333 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (277 aa) |
| | AEH23966.1 | Homoserine dehydrogenase. (320 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (965 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (164 aa) |
| | AEH23976.1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa) |
| | AEH23991.1 | Glycerol-3-phosphate cytidyltransferase. (138 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (211 aa) |
| | AEH23997.1 | Hypothetical protein. (261 aa) |
| | argS | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (629 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa) |
| | AEH24031.1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa) |
