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| | rbcL | Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (421 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (406 aa) |
| | fbp | Thermophile-specific fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (374 aa) |
| | AEH23754.1 | Hypothetical protein; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa) |
| | AEH23755.1 | acetyl-CoA acetyltransferase. (385 aa) |
| | AEH23760.1 | Magnesium chelatase, subunit ChlI family. (637 aa) |
| | AEH23761.1 | CobN/magnesium chelatase domain protein. (1252 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (444 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (234 aa) |
| | thiL | Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (314 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase. (334 aa) |
| | AEH23803.1 | GHMP kinase. (302 aa) |
| | mat | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa) |
| | moaC | Putative molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (154 aa) |
| | AEH23822.1 | Glucose-1-dehydrogenase. (268 aa) |
| | AEH23827.1 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (408 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa) |
| | AEH23833.1 | acetyl-CoA synthase. (473 aa) |
| | AEH23834.1 | Acetyl-CoA synthetase (ADP forming), beta chain (acdB). (238 aa) |
| | AEH23836.1 | Hypothetical protein. (201 aa) |
| | mptA | GTP cyclohydrolase; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (269 aa) |
| | adkA | Adenylate kinase; Belongs to the archaeal adenylate kinase family. (196 aa) |
| | AEH23873.1 | Sarcosine oxidase. (378 aa) |
| | AEH23876.1 | Sarcosine oxidase, subunit alpha. (475 aa) |
| | AEH23884.1 | UDP-glucose 4-epimerase. (317 aa) |
| | AEH23885.1 | AcdB acetate--coA ligase (ADP-forming), beta chain. (232 aa) |
| | AEH23918.1 | NDP-sugar synthase. (361 aa) |
| | tmk | Thymidylate kinase. (205 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | AEH23932.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma. (182 aa) |
| | AEH23933.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (281 aa) |
| | AEH23934.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (385 aa) |
| | AEH23935.1 | 2-oxoglutarate synthase subunit KorC. (171 aa) |
| | AEH23936.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (283 aa) |
| | AEH23937.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (396 aa) |
| | AEH23938.1 | 2-keto acid:ferredoxin oxidoreductase subunit delta. (89 aa) |
| | AEH23943.1 | Molybdenum cofactor biosynthesis protein MoeA. (394 aa) |
| | pfkC | ADP-specific phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (457 aa) |
| | AEH23957.1 | Enolase. (341 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (333 aa) |
| | AEH23961.1 | Amino acid kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (258 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase (fni); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (377 aa) |
| | AEH23964.1 | Bifunctional short chain isoprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (341 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (277 aa) |
| | AEH23966.1 | Homoserine dehydrogenase. (320 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (164 aa) |
| | AEH23976.1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa) |
| | AEH23991.1 | Glycerol-3-phosphate cytidyltransferase. (138 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (211 aa) |
| | AEH23997.1 | Hypothetical protein. (261 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa) |
| | AEH24018.1 | Lipoate-protein ligase a related protein. (249 aa) |
| | AEH24031.1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa) |
| | AEH24054.1 | UDP-N-acetylglucosamine 2-epimerase. (377 aa) |
| | AEH24055.1 | UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (418 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (285 aa) |
| | AEH24112.1 | Translation initiation factor IF-2B subunit beta; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (356 aa) |
| | AEH24140.1 | Phosphomethylpyrimidine kinase. (451 aa) |
| | AEH24150.1 | Pyrazinamidase/nicotinamidase. (181 aa) |
| | AEH24152.1 | Histidine triad protein. (110 aa) |
| | AEH24164.1 | 5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. (269 aa) |
| | AEH24178.1 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa) |
| | AEH24182.1 | dCMP deaminase. (181 aa) |
| | pdaD | Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. (158 aa) |
| | cmk | Cytidylate kinase. (192 aa) |
| | AEH24226.1 | Formaldehyde:ferredoxin oxidoreductase. (619 aa) |
| | hcp | Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (451 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (573 aa) |
| | AEH24264.1 | Dihydropteroate synthase. (272 aa) |
| | AEH24270.1 | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (315 aa) |
| | AEH24271.1 | methylmalonyl-CoA decarboxylase beta chain. (400 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (383 aa) |
| | AEH24311.1 | Myo-inositol-1-phosphate synthase. (383 aa) |
| | thi4 | Ribulose-1,5-biphosphate synthetase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (252 aa) |
| | thiC | Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (430 aa) |
| | AEH24314.1 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (219 aa) |
| | AEH24315.1 | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl. (310 aa) |
| | purO | IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (196 aa) |
| | cobB | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. (250 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A (mobA); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (191 aa) |
| | AEH24348.1 | Pyruvate ferredoxin oxidoreductase subunit beta. (331 aa) |
| | AEH24349.1 | Pyruvate ferredoxin oxidoreductase subunit alpha. (395 aa) |
| | AEH24350.1 | Pyuvate ferredoxin oxidoreductase subunit delta. (105 aa) |
| | AEH24351.1 | 2-ketoisovalerate ferredoxin oxidoreductase subunit beta. (311 aa) |
| | AEH24352.1 | 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha. (394 aa) |
| | AEH24353.1 | 2-ketoisovalerate ferredoxin oxidoreductase subunit delta. (105 aa) |
| | AEH24354.1 | Pyruvate ferredoxin oxidoreductase subunit gamma. (185 aa) |
| | AEH24358.1 | Fumarate hydratase. (278 aa) |
| | AEH24359.1 | Fumarate hydratase. (175 aa) |
| | AEH24360.1 | Aspartate racemase. (226 aa) |
| | AEH24361.1 | Cobalamin adenosyltransferase. (172 aa) |
| | AEH24368.1 | Arginase; Belongs to the arginase family. (243 aa) |
| | AEH24370.1 | Putative NTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (176 aa) |
| | AEH24376.1 | Formaldehyde:ferredoxin oxidoreductase wor5. (623 aa) |
| | AEH24377.1 | 4Fe-4S binding domain protein. (173 aa) |
| | AEH24383.1 | Mannosyl-3-phosphoglycerate synthase. (394 aa) |
| | mngB | Mannosyl-3-phosphoglycerate phosphatase; Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG). (243 aa) |
| | AEH24385.1 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl; Belongs to the mannose-6-phosphate isomerase type 2 family. (460 aa) |
| | AEH24387.1 | Phosphohexomutase. (456 aa) |
| | AEH24388.1 | Acetamidase/Formamidase family. (296 aa) |
| | AEH24394.1 | AcdA-3 acetate--coA ligase (ADP-forming), alpha chain. (455 aa) |
| | thyX | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (239 aa) |
| | AEH24410.1 | Asparagine synthase. (487 aa) |
| | AEH24412.1 | Threonine synthase. (443 aa) |
| | AEH24424.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (327 aa) |
| | AEH24426.1 | Alpha-amylase (intracellular); Belongs to the glycosyl hydrolase 57 family. (564 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic subunit. (308 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (151 aa) |
| | AEH24442.1 | Alpha-glucan phosphorylase. (836 aa) |
| | mtaD | 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (423 aa) |
| | pyrD | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. (298 aa) |
| | AEH24447.1 | ADP forming acetyl coenzyme A synthetase. (460 aa) |
| | AEH24456.1 | Arylmalonate decarboxylase. (236 aa) |
| | gcvT | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (401 aa) |
| | AEH24460.1 | Molybdenum cofactor biosynthesis protein MoeA. (400 aa) |
| | AEH24472.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa) |
| | AEH24477.1 | Carbamate kinase; Belongs to the carbamate kinase family. (314 aa) |
| | cobD | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (288 aa) |
| | AEH24493.1 | Putative aminotransferase. (323 aa) |
| | AEH24517.1 | ferredoxin-NADP(+) reductase subunit alpha. (289 aa) |
| | AEH24528.1 | Acetylornithine deacetylase. (350 aa) |
| | thi4-2 | Putative thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (263 aa) |
| | AEH24553.1 | Cystathionine gamma-lyase. (387 aa) |
| | AEH24554.1 | Pyridoxal-phosphate dependent enzyme superfamily. (389 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (363 aa) |
| | AEH24592.1 | Methyltransferase domain family. (243 aa) |
| | AEH24593.1 | Cystathionine gamma-lyase. (385 aa) |
| | AEH24594.1 | Pyridoxal-phosphate dependent enzyme superfamily. (390 aa) |
| | AEH24604.1 | Hydrolase. (226 aa) |
| | gyaR | Glyoxylate reductase. (333 aa) |
| | glmM | Phosphohexomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa) |
| | AEH24622.1 | Adenylyl cyclase, CyaB-type, putative. (176 aa) |
| | ubiX | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (186 aa) |
| | AEH24626.1 | NDP-sugar synthase. (413 aa) |
| | AEH24628.1 | Tungsten-containing aldehyde ferredoxin oxidoreductase. (606 aa) |
| | AEH24636.1 | Putative kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (185 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (232 aa) |
| | AEH24670.1 | Sarcosine oxidase, alpha subunit. (495 aa) |
| | AEH24671.1 | Sarcosine oxidase, beta subunit. (386 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (229 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (155 aa) |
| | ribK | Transcriptional regulator, MarR family; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (212 aa) |
| | tdh | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (348 aa) |
| | queE | Organic radical activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (253 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (733 aa) |
| | guaAA | GMP synthase subunit A; Catalyzes the synthesis of GMP from XMP. (188 aa) |
| | guaAB | GMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. (307 aa) |
| | purP | 5-aminoimidazole-4-carboxamide-1-beta-D- ribofuranosyl; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (331 aa) |
| | pdxT | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa) |
| | glkA | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. (462 aa) |
| | AEH24773.1 | Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (233 aa) |
| | AEH24775.1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa) |
| | AEH24777.1 | Coenzyme F420 hydrogenase alpha subunit. (391 aa) |
| | AEH24778.1 | Coenzyme F420 hydrogenase gamma subunit. (226 aa) |
| | AEH24779.1 | Coenzyme F420 hydrogenase/dehydrogenase beta subunit. (275 aa) |
| | AEH24784.1 | Hypothetical formate dehydrogenase, alpha subunit. (711 aa) |
| | AEH24802.1 | Pyridine nucleotide-disulfide oxidoreductase, putative. (351 aa) |
| | AEH24821.1 | Bifunctional phosphopantothenoylcysteine. (407 aa) |
| | AEH24822.1 | NADH dehydrogenase subunit I. (197 aa) |
| | AEH24823.1 | NADH dehydrogenase subunit D; Belongs to the complex I 49 kDa subunit family. (391 aa) |
| | AEH24824.1 | NADH dehydrogenase subunit C. (174 aa) |
| | AEH24825.1 | NADH dehydrogenase subunit B; Belongs to the complex I 20 kDa subunit family. (192 aa) |
| | AEH24826.1 | NADH dehydrogenase subunit. (309 aa) |
| | AEH24827.1 | NADH dehydrogenase subunit M. (618 aa) |
| | AEH24828.1 | NADH dehydrogenase subunit N. (495 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (437 aa) |
| | gatE | glutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (629 aa) |
| | AEH24849.1 | Thiamine biosynthesis protein (ThiI). (313 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (186 aa) |
| | AEH24862.1 | Alanine aminotransferase. (397 aa) |
| | AEH24865.1 | FwdE-like tungsten formylmethanofuran dehydrogenase, subunit E. (231 aa) |
| | AEH24884.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (450 aa) |
| | AEH24932.1 | dephospho-CoA kinase. (190 aa) |
| | AEH24935.1 | UDP-glucose 4-epimerase (galE). (315 aa) |
| | AEH24937.1 | Sugar-phosphate nucleotidyltransferase. (331 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (316 aa) |
| | AEH24944.1 | Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (278 aa) |
| | AEH24966.1 | Bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase. (253 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | AEH24973.1 | Putative 6-pyruvoyl tetrahydrobiopterin synthase. (149 aa) |
| | AEH24974.1 | D-arabino 3-hexulose 6-phosphate formaldehyde lyase. (406 aa) |
| | AEH24984.1 | CoA binding domain protein. (469 aa) |
| | AEH24986.1 | Glucose-1-phosphate thymidylyltransferase. (419 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (279 aa) |
| | AEH24998.1 | HAM1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (184 aa) |
| | AEH25006.1 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (178 aa) |
| | AEH25031.1 | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (395 aa) |
| | AEH25039.1 | 4-alpha-Glucanotransferase. (648 aa) |
| | AEH25050.1 | Acylphosphatase. (95 aa) |
| | guaB | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa) |
| | AEH25057.1 | Evolution of Prochlorococcus. (293 aa) |
| | AEH25062.1 | Phosphoserine phosphatase (serB). (206 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (225 aa) |
| | AEH25072.1 | Nicotinate phosphoribosyltransferase. (390 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (628 aa) |
| | AEH25107.1 | Biotin-protein ligase. (254 aa) |
| | AEH25148.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) |
| | queC | Transcription regulator, putative, ExsB family (ExsB); Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (239 aa) |
| | AEH25156.1 | Agmatinase; Belongs to the arginase family. (300 aa) |
| | AEH25157.1 | Fructose 1,6-bisphosphate aldolase class 1 (fba). (281 aa) |
| | AEH25168.1 | Histidine triad (HIT) protein (hit). (166 aa) |
| | AEH25173.1 | Dolichol monophosphate mannose synthase. (350 aa) |
| | AEH25218.1 | Putative glycerate kinase. (441 aa) |
| | AEH25234.1 | Hypothetical protein. (103 aa) |
| | AEH25235.1 | V-type ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family. (659 aa) |
| | AEH25236.1 | V-type ATP synthase subunit K. (159 aa) |
| | atpE | V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (203 aa) |
| | atpC | V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (370 aa) |
| | atpF | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (102 aa) |
| | atpA | ATP synthase archaeal, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (587 aa) |
| | atpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (464 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (213 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (244 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (408 aa) |
| | pgiA | Glucose-6-phosphate isomerase; Belongs to the archaeal-type GPI family. (189 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (216 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II, purL component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is th [...] (707 aa) |
| | AEH25264.1 | Ribonucleoside-diphosphate reductase alpha subunit (nrdA); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (897 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase. (333 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (429 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (143 aa) |
| | purD | Phosphoribosylamine--glycine ligase (purD); Belongs to the GARS family. (438 aa) |
| | AEH25273.1 | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl. (380 aa) |
| | mtnP | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (278 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (306 aa) |
| | AEH25298.1 | Ferredoxin 2. (64 aa) |
| | nadE | NAD synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (261 aa) |
| | AEH25303.1 | Molybdopterin-converting factor subunit 2. (144 aa) |
| | AEH25328.1 | Aminotransferase, classes I and II superfamily. (413 aa) |
| | speE | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (278 aa) |
| | AEH25345.1 | L-asparaginase. (306 aa) |
| | AEH25347.1 | Biotin synthase-related protein. (318 aa) |
| | AEH25350.1 | Diaminopimelate aminotransferase. (419 aa) |
| | AEH25353.1 | Phosphoadenosine phosphosulfate reductase family protein. (632 aa) |
| | AEH25357.1 | methylmalonyl-CoA epimerase. (133 aa) |
| | AEH25366.1 | Cyclomaltodextrinase. (656 aa) |
| | speH | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (140 aa) |
| | pxpA | Lactam utilization related protein (lamB); Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (254 aa) |
| | AEH25380.1 | Allophanate hydrolase, subunit 2. (319 aa) |
| | AEH25387.1 | cob(I)alamin adenosyltransferase. (175 aa) |
| | AEH25393.1 | Glycogen synthase. (461 aa) |
| | AEH25396.1 | L-asparaginase. (328 aa) |
| | AEH25401.1 | Adenosylcobinamide amidohydrolase (AdoCbi hydrolase) (CbiZ). (202 aa) |
| | cobS | Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (229 aa) |
| | AEH25405.1 | GTP:adenosylcobinamide-phosphate guanylyltransferase. (181 aa) |
| | AEH25406.1 | Naerobic ribonucleoside triphosphate reductase. (500 aa) |
| | AEH25409.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (467 aa) |
| | sat | Sulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (379 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (178 aa) |
| | AEH25421.1 | dTDP-D-Fucp3N acetylase. (219 aa) |
| | AEH25425.1 | NDP-sugar dehydrogenase. (427 aa) |
| | AEH25426.1 | UTP-glucose-1-phosphate uridylyltransferase (galU). (286 aa) |
| | AEH25428.1 | dTDP-4-dehydrorhamnose reductase. (285 aa) |
| | AEH25433.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | AEH25436.1 | dTDP-glucose 4,6-dehydratase. (333 aa) |
| | AEH25437.1 | Glucose-1-phosphate thymidylyltransferase. (352 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (156 aa) |
| | gcvPA | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (464 aa) |
| | gcvPB | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (501 aa) |
| | glpK | Glycerol kinase (glpK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (493 aa) |
| | ahcY | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (422 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa) |
| | AEH25510.1 | Cytoplasmic alpha-amylase. (458 aa) |
| | AEH25524.1 | Tungsten-containing glyceraldehyde-3-phosphate:ferredoxin. (656 aa) |
| | AEH25525.1 | 2-haloalkanoic acid dehalogenase-like hydrolase. (235 aa) |
| | AEH25532.1 | Nicotinamide-nucleotide adenylyltransferase. (188 aa) |
| | AEH25546.1 | Glutamine synthetase. (441 aa) |
| | AEH25550.1 | D-isomer specific 2-hydroxyacid dehydrogenase. (333 aa) |
| | AEH25555.1 | Molybdenum cofactor biosynthesis protein. (168 aa) |
| | AEH25564.1 | parB-like nuclease, putative. (242 aa) |
| | AEH25566.1 | nifS protein. (398 aa) |
| | glmS | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa) |
