(59 nodes) Response to organonitrogen compound network (Nannizzia gypsea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LCL2	Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (122 aa)
	MGYG_03881	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	MGYG_03834	Ubiquitin fusion degradation protein 1. (393 aa)
	MGYG_06596	Transcriptional activator protein DAL81. (730 aa)
	MGYG_07370	UBIQUITIN_CONJUGAT_2 domain-containing protein. (292 aa)
	MGYG_05026	E3 ubiquitin-protein ligase synoviolin-A. (823 aa)
	MGYG_06376	Zn(2)-C6 fungal-type domain-containing protein. (523 aa)
	MGYG_06506	Uncharacterized protein. (250 aa)
	MGYG_05900	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1050 aa)
	MGYG_05952	N-acetyltransferase domain-containing protein. (190 aa)
	MGYG_09105	Uncharacterized protein. (1083 aa)
	MGYG_06646	TPR_REGION domain-containing protein. (373 aa)
	MGYG_06943	SEL1L. (803 aa)
	MGYG_07081	UBX domain-containing protein. (526 aa)
	MGYG_01727	Cytidylyltransferase. (290 aa)
	MGYG_01737	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (587 aa)
	MGYG_01047	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (597 aa)
	MGYG_07375	Ubiquitin fusion degradation protein 1. (760 aa)
	MGYG_07723	Uncharacterized protein; Belongs to the AAA ATPase family. (814 aa)
	MGYG_07782	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (581 aa)
	MGYG_07207	GTP-binding protein GTR2. (386 aa)
	MGYG_04747	Proteasome component ECM29. (1852 aa)
	MGYG_05544	UBX domain-containing protein. (481 aa)
	MGYG_04704	26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. (393 aa)
	MGYG_04703	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (719 aa)
	MGYG_04698	UBX domain-containing protein. (523 aa)
	MGYG_04679	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (457 aa)
	MGYG_04117	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (263 aa)
	MGYG_04025	GTP-binding protein GTR1. (338 aa)
	MGYG_02158	RING finger membrane protein. (1628 aa)
	MGYG_02805	Acetyl esterase. (341 aa)
	MGYG_02632	Abhydrolase_3 domain-containing protein. (489 aa)
	MGYG_02631	J domain-containing protein. (305 aa)
	MGYG_05701	Ubiquitin thioesterase OTU1. (327 aa)
	MGYG_05021	J domain-containing protein. (478 aa)
	MGYG_05087	PRKCSH domain-containing protein. (577 aa)
	MGYG_07803	UBIQUITIN_CONJUGAT_2 domain-containing protein. (329 aa)
	MGYG_07975	Glucose-regulated protein; Belongs to the heat shock protein 70 family. (676 aa)
	MGYG_08004	Chaperone dnaJ. (418 aa)
	MGYG_08809	Uncharacterized protein. (405 aa)
	MGYG_00329	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (248 aa)
	MGYG_00463	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (899 aa)
	MGYG_00467	BAH domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1091 aa)
	MGYG_00515	WD repeat-containing protein mip1. (1408 aa)
	MGYG_00545	UDP-glucose:glycoprotein glucosyltransferase. (1489 aa)
	MGYG_04606	Cross-pathway control protein A. (239 aa)
	MGYG_03737	PEK/GCN2 protein kinase. (1590 aa)
	MGYG_03641	Ubiquitin-conjugating enzyme E2 1; Belongs to the ubiquitin-conjugating enzyme family. (245 aa)
	MGYG_04381	Alpha/beta hydrolase fold-3 domain-containing protein. (338 aa)
	MGYG_04368	Nitrogen metabolic regulation protein. (344 aa)
	MGYG_04365	Methyltranfer_dom domain-containing protein. (671 aa)
	MGYG_04339	Transporter SEC61 subunit alpha. (434 aa)
	MGYG_01540	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (509 aa)
	MGYG_01723	Ubiquitin conjugation factor E4. (1052 aa)
	MGYG_01725	Hlj1 protein. (351 aa)
	MGYG_03505	Ankyrin repeat and zinc finger domain-containing protein 1. (658 aa)
	MGYG_04325	Nucleotide excision repair protein RAD23. (380 aa)
	MGYG_03071	Ubiquitin-protein ligase E3C. (1209 aa)
	MGYG_02981	Protein kinase subdomain-containing protein. (938 aa)

Your Current Organism:

Nannizzia gypsea

NCBI taxonomy Id: 535722
Other names: Arthroderma gypseum CBS 118893, Microsporum gypseum CBS 118893, N. gypsea CBS 118893, Nannizzia gypsea CBS 118893

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MGYG_00329	MGYG_02158	E5QZ56	E4UQ12	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	RING finger membrane protein.	0.566
MGYG_00329	MGYG_03834	E5QZ56	E4UU63	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Ubiquitin fusion degradation protein 1.	0.970
MGYG_00329	MGYG_03881	E5QZ56	E4UUB1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.	0.433
MGYG_00329	MGYG_04117	E5QZ56	E4UUZ6	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.989
MGYG_00329	MGYG_04325	E5QZ56	E4USB4	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Nucleotide excision repair protein RAD23.	0.727
MGYG_00329	MGYG_04339	E5QZ56	E4USI1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Transporter SEC61 subunit alpha.	0.653
MGYG_00329	MGYG_05026	E5QZ56	E4UY31	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	E3 ubiquitin-protein ligase synoviolin-A.	0.997
MGYG_00329	MGYG_05087	E5QZ56	E4UYC1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	PRKCSH domain-containing protein.	0.996
MGYG_00329	MGYG_05544	E5QZ56	E4UWF2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBX domain-containing protein.	0.852
MGYG_00329	MGYG_05900	E5QZ56	E4UZW2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.560
MGYG_00329	MGYG_06943	E5QZ56	E4V1N0	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	SEL1L.	0.999
MGYG_00329	MGYG_07081	E5QZ56	E4V210	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBX domain-containing protein.	0.882
MGYG_00329	MGYG_07370	E5QZ56	E4V2Y8	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.670
MGYG_00329	MGYG_07375	E5QZ56	E4V2Z3	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Ubiquitin fusion degradation protein 1.	0.708
MGYG_00329	MGYG_07723	E5QZ56	E4V3Z1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.986
MGYG_00329	MGYG_07803	E5QZ56	E4V472	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.529
MGYG_00329	MGYG_07975	E5QZ56	E4V4P9	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Glucose-regulated protein; Belongs to the heat shock protein 70 family.	0.908
MGYG_00463	MGYG_01047	E5QZV9	E5R3V1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.760
MGYG_00463	MGYG_04703	E5QZV9	E4UW92	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.931
MGYG_00515	MGYG_03737	E5R064	E4UTM3	WD repeat-containing protein mip1.	PEK/GCN2 protein kinase.	0.941