STRINGSTRING
MGYG_08157 MGYG_08157 MGYG_01905 MGYG_01905 MGYG_01917 MGYG_01917 MGYG_01918 MGYG_01918 DRE2 DRE2 MGYG_01237 MGYG_01237 MGYG_00456 MGYG_00456 MGYG_01430 MGYG_01430 MGYG_01515 MGYG_01515 MGYG_00568 MGYG_00568 MGYG_02544 MGYG_02544 MGYG_02604 MGYG_02604 MGYG_02025 MGYG_02025 CFD1 CFD1 MGYG_03708 MGYG_03708 MGYG_05379 MGYG_05379 NBP35 NBP35 MGYG_05506 MGYG_05506 MGYG_05569 MGYG_05569 MGYG_06381 MGYG_06381 MGYG_06441 MGYG_06441 MGYG_06029 MGYG_06029 MGYG_06852 MGYG_06852 MGYG_06870 MGYG_06870 MGYG_07787 MGYG_07787
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MGYG_08157DNA polymerase. (1465 aa)
MGYG_01905Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (148 aa)
MGYG_01917Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (201 aa)
MGYG_01918NADH dehydrogenase iron-sulfur protein 7; Belongs to the complex I 20 kDa subunit family. (227 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (305 aa)
MGYG_01237Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (652 aa)
MGYG_00456Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
MGYG_01430Biotin synthase. (402 aa)
MGYG_01515Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (801 aa)
MGYG_00568DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2231 aa)
MGYG_02544NADH-ubiquinone oxidoreductase subunit; Belongs to the complex I 20 kDa subunit family. (191 aa)
MGYG_02604Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (284 aa)
MGYG_02025NADH-ubiquinone oxidoreductase subunit. (267 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (327 aa)
MGYG_03708Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (576 aa)
MGYG_05379Pyruvate formate lyase activating enzyme. (365 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (330 aa)
MGYG_05506DNA polymerase. (1681 aa)
MGYG_05569Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (413 aa)
MGYG_06381Glutamate synthase. (2132 aa)
MGYG_06441Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (792 aa)
MGYG_06029DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (478 aa)
MGYG_06852NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (535 aa)
MGYG_06870Xanthine dehydrogenase. (1355 aa)
MGYG_07787DNA polymerase. (1112 aa)
Your Current Organism:
Nannizzia gypsea
NCBI taxonomy Id: 535722
Other names: Arthroderma gypseum CBS 118893, Microsporum gypseum CBS 118893, N. gypsea CBS 118893, Nannizzia gypsea CBS 118893
Server load: low (20%) [HD]