STRINGSTRING
rsgA rsgA AKN29421.1 AKN29421.1 thiC thiC AKN29548.1 AKN29548.1 AKN29553.1 AKN29553.1 AKN29554.1 AKN29554.1 thiG thiG AKN29556.1 AKN29556.1 cbiM cbiM cbiN cbiN AKN29589.1 AKN29589.1 AKN29590.1 AKN29590.1 AKN29701.1 AKN29701.1 AKN29745.1 AKN29745.1 AKN29838.1 AKN29838.1 thiM thiM AKN30074.1 AKN30074.1 AKN30095.1 AKN30095.1 AKN30232.1 AKN30232.1 AKN30233.1 AKN30233.1 AKN34122.1 AKN34122.1 AKN30234.1 AKN30234.1 AKN30235.1 AKN30235.1 AKN30564.1 AKN30564.1 AKN30566.1 AKN30566.1 AKN30567.1 AKN30567.1 AKN30568.1 AKN30568.1 AKN30569.1 AKN30569.1 AKN30659.1 AKN30659.1 AKN30704.1 AKN30704.1 AKN30705.1 AKN30705.1 AKN31010.1 AKN31010.1 AKN31162.1 AKN31162.1 AKN31163.1 AKN31163.1 cbiN-2 cbiN-2 cbiM-2 cbiM-2 AKN31460.1 AKN31460.1 AKN31461.1 AKN31461.1 AKN31462.1 AKN31462.1 AKN31469.1 AKN31469.1 AKN31470.1 AKN31470.1 AKN31471.1 AKN31471.1 AKN31472.1 AKN31472.1 AKN31473.1 AKN31473.1 AKN31474.1 AKN31474.1 AKN31475.1 AKN31475.1 AKN31476.1 AKN31476.1 AKN31477.1 AKN31477.1 AKN31478.1 AKN31478.1 AKN31479.1 AKN31479.1 AKN31482.1 AKN31482.1 AKN31483.1 AKN31483.1 AKN31485.1 AKN31485.1 AKN31486.1 AKN31486.1 AKN31487.1 AKN31487.1 AKN31488.1 AKN31488.1 AKN31489.1 AKN31489.1 AKN31490.1 AKN31490.1 AKN31491.1 AKN31491.1 AKN31492.1 AKN31492.1 AKN31500.1 AKN31500.1 AKN31501.1 AKN31501.1 AKN31502.1 AKN31502.1 AKN31503.1 AKN31503.1 AKN31504.1 AKN31504.1 nikC nikC AKN31506.1 AKN31506.1 AKN31507.1 AKN31507.1 AKN31508.1 AKN31508.1 AKN31509.1 AKN31509.1 AKN31848.1 AKN31848.1 AKN31928.1 AKN31928.1 AKN32085.1 AKN32085.1 AKN32086.1 AKN32086.1 AKN32096.1 AKN32096.1 AKN32164.1 AKN32164.1 AKN32165.1 AKN32165.1 AKN32166.1 AKN32166.1 AKN32167.1 AKN32167.1 AKN32168.1 AKN32168.1 AKN32169.1 AKN32169.1 cbiF cbiF AKN32171.1 AKN32171.1 AKN32172.1 AKN32172.1 AKN32173.1 AKN32173.1 cbiD cbiD cbiC cbiC cobT cobT AKN32177.1 AKN32177.1 hemL hemL AKN32179.1 AKN32179.1 AKN32180.1 AKN32180.1 hemC hemC AKN32182.1 AKN32182.1 hemA hemA AKN32184.1 AKN32184.1 cobD cobD cobQ cobQ AKN32186.1 AKN32186.1 AKN32187.1 AKN32187.1 AKN32238.1 AKN32238.1 AKN32555.1 AKN32555.1 AKN32671.1 AKN32671.1 cobS cobS AKN32708.1 AKN32708.1 AKN32799.1 AKN32799.1 ecfT ecfT AKN32946.1 AKN32946.1 ecfA ecfA AKN33229.1 AKN33229.1 AKN33271.1 AKN33271.1 AKN33330.1 AKN33330.1 AKN33331.1 AKN33331.1 AKN33332.1 AKN33332.1 AKN33333.1 AKN33333.1 AKN33615.1 AKN33615.1 AKN33627.1 AKN33627.1 thiM-2 thiM-2 thiE thiE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rsgARibosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (288 aa)
AKN29421.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (437 aa)
AKN29548.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AKN29553.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
AKN29554.1Thiamine biosynthesis protein ThiF; Catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa)
AKN29556.1Thiamine biosynthesis protein ThiH; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
cbiMCobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (246 aa)
cbiNCobalamin biosynthesis protein CbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (104 aa)
AKN29589.1Cobalt ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AKN29590.1Cobalt ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
AKN29701.1Thiaminase; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (219 aa)
AKN29745.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AKN29838.1Thiamine biosynthesis protein ThiW; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (265 aa)
AKN30074.1Biotin biosynthesis protein BioY; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AKN30095.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
AKN30232.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
AKN30233.1Peptide ABC transporter permease; Transports peptides consisting of two or three amino acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AKN34122.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AKN30234.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (323 aa)
AKN30235.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (320 aa)
AKN30564.1Cyclic nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
AKN30566.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AKN30567.1Cobalt ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AKN30568.1Cobalt ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AKN30569.1Cobalt ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
AKN30659.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AKN30704.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
AKN30705.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
AKN31010.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (823 aa)
AKN31162.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (238 aa)
AKN31163.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (643 aa)
cbiN-2Cobalt ABC transporter; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (116 aa)
cbiM-2Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (250 aa)
AKN31460.1ATP-binding protein; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (284 aa)
AKN31461.1Cobalt ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AKN31462.1Precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AKN31469.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1146 aa)
AKN31470.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (639 aa)
AKN31471.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AKN31472.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AKN31473.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
AKN31474.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
AKN31475.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AKN31476.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
AKN31477.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
AKN31478.1Cobalt transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AKN31479.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1211 aa)
AKN31482.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
AKN31483.1Cyclopropane-fatty-acyl-phospholipid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AKN31485.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AKN31486.1Nickel ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AKN31487.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
AKN31488.1Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
AKN31489.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (526 aa)
AKN31490.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AKN31491.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
AKN31492.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
AKN31500.1Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
AKN31501.1Succinylglutamate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AKN31502.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (323 aa)
AKN31503.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AKN31504.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
nikCNickel transporter permease NikC; With NikABDE is involved in nickel transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AKN31506.1Nickel transporter permease NikB; With NikACDE is involved in nickel transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AKN31507.1Ubiquinone biosynthesis methyltransferase UbiE; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
AKN31508.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (71 aa)
AKN31509.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
AKN31848.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (202 aa)
AKN31928.1Biotin biosynthesis protein BioY; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AKN32085.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AKN32086.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
AKN32096.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AKN32164.1Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
AKN32165.1Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
AKN32166.1cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AKN32167.1Sirohydrochlorin cobaltochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AKN32168.1cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
AKN32169.1Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
cbiFCatalyzes the formation of cobalt-precorrin-5 from cobalt-precorrin-4; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
AKN32171.1Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. (228 aa)
AKN32172.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
AKN32173.1precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
cbiDcobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (362 aa)
cbiCCatalyzes the interconversion of precorrin-8X and cobyrinic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (357 aa)
AKN32177.1Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
AKN32179.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (323 aa)
AKN32180.1Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (290 aa)
AKN32182.1Precorrin-2 dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (398 aa)
AKN32184.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (319 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (505 aa)
AKN32186.1Cobalt ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
AKN32187.1Cobalt permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AKN32238.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1086 aa)
AKN32555.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
AKN32671.1Cobinamide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (252 aa)
AKN32708.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
AKN32799.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
ecfTTransporter; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (268 aa)
AKN32946.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
ecfACobalt transporter ATP-binding subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (281 aa)
AKN33229.1Proton-coupled thiamine transporter YuaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
AKN33271.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
AKN33330.1Membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. (207 aa)
AKN33331.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
AKN33332.1Flagellar biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
AKN33333.1Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
AKN33615.1Cobalamin biosynthesis protein CbiM; Catalyzes the ATP-dependent transport of cobalt; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
AKN33627.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
thiM-2Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (270 aa)
thiEThiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (204 aa)
Your Current Organism:
Clostridium carboxidivorans
NCBI taxonomy Id: 536227
Other names: C. carboxidivorans P7, Clostridium carboxidivorans P7, Clostridium carboxidivorans str. P7, Clostridium carboxidivorans strain P7
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