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| | dapA | Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | nrdR | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (158 aa) |
| | RibD | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (374 aa) |
| | GCA_001696535_00101 | Unannotated protein. (200 aa) |
| | ribH | Unannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (148 aa) |
| | nusB | Unannotated protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (175 aa) |
| | hppA | Unannotated protein; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (711 aa) |
| | RocF | Unannotated protein; Belongs to the arginase family. (317 aa) |
| | rocD | Unannotated protein; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (403 aa) |
| | GCA_001696535_00143 | Unannotated protein. (405 aa) |
| | GCA_001696535_00144 | Unannotated protein. (440 aa) |
| | GCA_001696535_00227 | Unannotated protein. (190 aa) |
| | coaD | Unannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (168 aa) |
| | ispDF | Unannotated protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (419 aa) |
| | trpD | Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (342 aa) |
| | trpC | Unannotated protein; Belongs to the TrpC family. (269 aa) |
| | purM | Unannotated protein. (359 aa) |
| | purN | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (201 aa) |
| | purF | Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa) |
| | GCA_001696535_00478 | Unannotated protein. (461 aa) |
| | GlnA | Unannotated protein. (469 aa) |
| | gmk | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. (231 aa) |
| | GCA_001696535_00584 | Unannotated protein. (298 aa) |
| | aroQ | Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | pyrB | Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (318 aa) |
| | GCA_001696535_00670 | Unannotated protein. (431 aa) |
| | HydA | Unannotated protein. (469 aa) |
| | guaA | Unannotated protein; Catalyzes the synthesis of GMP from XMP. (521 aa) |
| | GCA_001696535_00785 | Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (432 aa) |
| | guaB | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa) |
| | katG | Unannotated protein; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (734 aa) |
| | GCA_001696535_00897 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa) |
| | pyrE | Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (231 aa) |
| | folE | Unannotated protein. (211 aa) |
| | hisI | Unannotated protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (150 aa) |
| | gpt | Unannotated protein; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (169 aa) |
| | ispE | Unannotated protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (327 aa) |
| | GCA_001696535_01088 | Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (442 aa) |
| | purC | Unannotated protein; Belongs to the SAICAR synthetase family. (254 aa) |
| | purS | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (79 aa) |
| | purQ | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (224 aa) |
| | purL | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (732 aa) |
| | GCA_001696535_01252 | Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (180 aa) |
| | GCA_001696535_01262 | Unannotated protein. (298 aa) |
| | thyA | Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | GCA_001696535_01321 | Unannotated protein. (1200 aa) |
| | carA | Unannotated protein; Belongs to the CarA family. (403 aa) |
| | carB | Unannotated protein; Belongs to the CarB family. (1104 aa) |
| | GCA_001696535_01477 | Unannotated protein. (399 aa) |
| | proC | Unannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa) |
| | GCA_001696535_01611 | Unannotated protein. (595 aa) |
| | GCA_001696535_01658 | Unannotated protein. (386 aa) |
| | GltD | Unannotated protein. (476 aa) |
| | GltB | Unannotated protein. (1578 aa) |
| | GCA_001696535_01724 | Unannotated protein. (263 aa) |
| | purK | Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (367 aa) |
| | purE | Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa) |
| | GCA_001696535_01772 | Unannotated protein; Belongs to the inositol monophosphatase superfamily. (264 aa) |
| | GCA_001696535_01801 | Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (391 aa) |
| | GCA_001696535_01802 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | purA | Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | GCA_001696535_01861 | Unannotated protein. (370 aa) |
| | GCA_001696535_02068 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (345 aa) |
| | GCA_001696535_02074 | Unannotated protein. (283 aa) |
| | pyrD | Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate. (314 aa) |
| | GCA_001696535_02076 | Unannotated protein. (427 aa) |
| | pyrC | Unannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (349 aa) |
| | GCA_001696535_02179 | Unannotated protein. (527 aa) |
| | GCA_001696535_02216 | Unannotated protein. (271 aa) |
| | nbaC | Unannotated protein; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (180 aa) |
| | ArgE | Unannotated protein. (387 aa) |
| | PutA | Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1047 aa) |
| | dapE | Unannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (390 aa) |
| | dapD | Unannotated protein; Belongs to the transferase hexapeptide repeat family. (286 aa) |
| | argB | Unannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa) |
| | GCA_001696535_02475 | Unannotated protein; Belongs to the glutamine synthetase family. (463 aa) |
| | GCA_001696535_02477 | Unannotated protein; Belongs to the glutamine synthetase family. (465 aa) |
| | GCA_001696535_02503 | Unannotated protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (468 aa) |
| | hisS | Unannotated protein. (507 aa) |
| | GCA_001696535_02541 | Unannotated protein. (375 aa) |
| | GCA_001696535_02542 | Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (332 aa) |
| | GCA_001696535_02556 | Unannotated protein. (239 aa) |
| | lspA | Unannotated protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (171 aa) |
| | GCA_001696535_02558 | Unannotated protein. (317 aa) |
| | GCA_001696535_02559 | Unannotated protein; Belongs to the ribF family. (333 aa) |
| | GCA_001696535_02581 | Unannotated protein. (80 aa) |
| | GCA_001696535_02582 | Unannotated protein. (268 aa) |
| | purD | Unannotated protein; Belongs to the GARS family. (428 aa) |
| | GCA_001696535_02602 | Unannotated protein. (489 aa) |
| | thrB | Unannotated protein; Belongs to the pseudomonas-type ThrB family. (321 aa) |
| | ispH | Unannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (327 aa) |
| | nadA | Unannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (361 aa) |
| | GCA_001696535_02654 | Unannotated protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. (542 aa) |
| | GCA_001696535_02655 | Unannotated protein; Belongs to the NadC/ModD family. (289 aa) |
| | aroC | Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | ribB | Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (439 aa) |
| | dxs | Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa) |
| | argD | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa) |
| | ArgF | Unannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (310 aa) |
| | hisD | Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa) |
| | GCA_001696535_03007 | Unannotated protein. (287 aa) |
| | aroQ-2 | Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) |
| | GCA_001696535_03036 | Unannotated protein. (609 aa) |
| | GCA_001696535_03086 | Unannotated protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (390 aa) |
| | GCA_001696535_03088 | Unannotated protein. (414 aa) |
| | GCA_001696535_03222 | Unannotated protein. (728 aa) |
| | ArgE-2 | Unannotated protein. (388 aa) |
| | SerA | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (414 aa) |
| | GCA_001696535_03245 | Unannotated protein. (423 aa) |
| | fhs | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. (556 aa) |
| | GCA_001696535_03565 | Unannotated protein. (403 aa) |
| | GCA_001696535_03594 | Unannotated protein. (460 aa) |
| | GCA_001696535_03618 | Unannotated protein. (218 aa) |
| | dapB | Unannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (270 aa) |
| | GCA_001696535_03760 | Unannotated protein. (296 aa) |
| | aroA | Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (451 aa) |
| | proA | Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (426 aa) |
| | proB | Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (401 aa) |
| | GCA_001696535_04022 | Unannotated protein. (625 aa) |
| | GCA_001696535_04061 | Unannotated protein; Belongs to the aspartokinase family. (416 aa) |
| | argJ | Unannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (410 aa) |
| | AsnB | Unannotated protein. (651 aa) |
| | purH | Unannotated protein. (538 aa) |
| | GCA_001696535_04132 | Unannotated protein. (410 aa) |
| | ispG | Unannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (422 aa) |
| | folD | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa) |
| | GCA_001696535_04202 | Unannotated protein. (105 aa) |
| | Hpt | Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | lysA | Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (424 aa) |
| | argH | Unannotated protein. (465 aa) |
| | dapF | Unannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (302 aa) |
| | argC | Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (316 aa) |
| | GCA_001696535_04259 | Unannotated protein. (1598 aa) |
| | GCA_001696535_04264 | Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa) |
| | FolK | Unannotated protein. (169 aa) |
| | GCA_001696535_04266 | Unannotated protein. (306 aa) |
| | hisC | Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (373 aa) |
| | argG | Unannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa) |
| | GCA_001696535_04317 | Unannotated protein; Belongs to the FPP/GGPP synthase family. (301 aa) |
| | aroK | Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (206 aa) |
| | aroB | Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (384 aa) |
| | asd | Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | Ggt | Unannotated protein. (591 aa) |
| | PpsR | Unannotated protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (283 aa) |
| | GCA_001696535_04393 | Unannotated protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (198 aa) |
| | aroE | Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa) |
| | coaE | Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (195 aa) |
| | trpF | Unannotated protein; Belongs to the TrpF family. (230 aa) |
| | trpB | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa) |
| | GCA_001696535_04462 | Unannotated protein; Belongs to the glutamine synthetase family. (455 aa) |
| | trpA | Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (276 aa) |
| | GCA_001696535_04467 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. (436 aa) |
| | coaA | Unannotated protein. (324 aa) |
| | hisE | Unannotated protein. (107 aa) |
| | hisF | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa) |
| | hisA | Unannotated protein. (243 aa) |
| | hisH | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa) |
| | hisB | Unannotated protein. (197 aa) |
| | pyrF | Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (249 aa) |
| | dut | Unannotated protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa) |
| | CoaBC | Unannotated protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa) |
| | GCA_001696535_04528 | Unannotated protein. (451 aa) |
| | PreA | Unannotated protein. (436 aa) |
| | GCA_001696535_04535 | Unannotated protein. (416 aa) |
| | HydA-2 | Unannotated protein. (485 aa) |
