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| | cobS | Unannotated protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (275 aa) |
| | cobT | Unannotated protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (340 aa) |
| | GCA_001696535_00019 | Unannotated protein. (139 aa) |
| | GCA_001696535_00027 | Unannotated protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (429 aa) |
| | GCA_001696535_00028 | Unannotated protein. (184 aa) |
| | mobA | Unannotated protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (208 aa) |
| | fdhD | Unannotated protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (306 aa) |
| | GCA_001696535_00052 | Unannotated protein. (209 aa) |
| | moaA | Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (333 aa) |
| | pdxJ | Unannotated protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (249 aa) |
| | rpoZ | Unannotated protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (135 aa) |
| | HemB | Unannotated protein; Belongs to the ALAD family. (344 aa) |
| | RibD | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (374 aa) |
| | GCA_001696535_00101 | Unannotated protein. (200 aa) |
| | ribH | Unannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (148 aa) |
| | nusB | Unannotated protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (175 aa) |
| | ctaA | Unannotated protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (367 aa) |
| | GCA_001696535_00159 | Unannotated protein. (203 aa) |
| | GCA_001696535_00160 | Unannotated protein. (336 aa) |
| | GCA_001696535_00196 | Unannotated protein. (357 aa) |
| | tmk | Unannotated protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (223 aa) |
| | tgt | Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] (381 aa) |
| | queA | Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (361 aa) |
| | glmU | Unannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (453 aa) |
| | GCA_001696535_00227 | Unannotated protein. (190 aa) |
| | coaD | Unannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (168 aa) |
| | GCA_001696535_00240 | Unannotated protein. (425 aa) |
| | GCA_001696535_00265 | Unannotated protein; Belongs to the CinA family. (174 aa) |
| | lipA | Unannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (327 aa) |
| | GCA_001696535_00274 | Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (464 aa) |
| | pdhA | Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (350 aa) |
| | pyrG | Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa) |
| | trpD | Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (342 aa) |
| | trpC | Unannotated protein; Belongs to the TrpC family. (269 aa) |
| | moaC | Unannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (173 aa) |
| | GCA_001696535_00314 | Unannotated protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (404 aa) |
| | pyrH | Unannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa) |
| | DnaE | Unannotated protein. (1146 aa) |
| | serS | Unannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | napA | Unannotated protein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (833 aa) |
| | purM | Unannotated protein. (359 aa) |
| | purN | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (201 aa) |
| | ndk | Unannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (191 aa) |
| | GCA_001696535_00452 | Unannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (493 aa) |
| | purF | Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa) |
| | nadE | Unannotated protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (570 aa) |
| | GCA_001696535_00574 | Unannotated protein. (149 aa) |
| | pdxA | Unannotated protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (339 aa) |
| | gmk | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. (231 aa) |
| | AccC | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | GCA_001696535_00621 | Unannotated protein. (173 aa) |
| | GCA_001696535_00632 | Unannotated protein. (135 aa) |
| | GCA_001696535_00634 | Unannotated protein. (283 aa) |
| | pyrB | Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (318 aa) |
| | GCA_001696535_00670 | Unannotated protein. (431 aa) |
| | dinB | Unannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (452 aa) |
| | GCA_001696535_00723 | Unannotated protein. (414 aa) |
| | HydA | Unannotated protein. (469 aa) |
| | GCA_001696535_00755 | Unannotated protein. (271 aa) |
| | guaA | Unannotated protein; Catalyzes the synthesis of GMP from XMP. (521 aa) |
| | guaB | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa) |
| | queF | Unannotated protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (155 aa) |
| | GCA_001696535_00837 | Unannotated protein. (791 aa) |
| | GCA_001696535_00859 | Unannotated protein. (474 aa) |
| | GCA_001696535_00869 | Unannotated protein. (240 aa) |
| | GCA_001696535_00871 | Unannotated protein. (275 aa) |
| | GCA_001696535_00897 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa) |
| | rpoA | Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa) |
| | adk | Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (198 aa) |
| | rpoC | Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1399 aa) |
| | rpoB | Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1380 aa) |
| | nusG | Unannotated protein; Participates in transcription elongation, termination and antitermination. (176 aa) |
| | GCA_001696535_00969 | Unannotated protein. (664 aa) |
| | pyrE | Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (231 aa) |
| | nadK | Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (260 aa) |
| | folE | Unannotated protein. (211 aa) |
| | GCA_001696535_01035 | Unannotated protein. (247 aa) |
| | gpt | Unannotated protein; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (169 aa) |
| | ackA | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa) |
| | GCA_001696535_01049 | Unannotated protein. (464 aa) |
| | purU | Unannotated protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa) |
| | GCA_001696535_01063 | Unannotated protein. (89 aa) |
| | GCA_001696535_01088 | Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (442 aa) |
| | purC | Unannotated protein; Belongs to the SAICAR synthetase family. (254 aa) |
| | purS | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (79 aa) |
| | purQ | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (224 aa) |
| | purL | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (732 aa) |
| | GCA_001696535_01107 | Unannotated protein; Belongs to the BolA/IbaG family. (77 aa) |
| | GCA_001696535_01221 | Unannotated protein. (767 aa) |
| | GCA_001696535_01242 | Unannotated protein. (293 aa) |
| | GCA_001696535_01252 | Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (180 aa) |
| | GCA_001696535_01255 | Unannotated protein. (179 aa) |
| | thyA | Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | GCA_001696535_01449 | Unannotated protein. (136 aa) |
| | rpoD | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (682 aa) |
| | dnaG | Unannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (695 aa) |
| | carA | Unannotated protein; Belongs to the CarA family. (403 aa) |
| | carB | Unannotated protein; Belongs to the CarB family. (1104 aa) |
| | MoaD | Unannotated protein. (83 aa) |
| | GCA_001696535_01508 | Unannotated protein. (164 aa) |
| | prs | Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | GCA_001696535_01538 | Unannotated protein. (228 aa) |
| | apt | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa) |
| | mtnP | Unannotated protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (291 aa) |
| | hemF | Unannotated protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (312 aa) |
| | GCA_001696535_01550 | Unannotated protein. (373 aa) |
| | GCA_001696535_01601 | Unannotated protein. (658 aa) |
| | GCA_001696535_01659 | Unannotated protein. (567 aa) |
| | GCA_001696535_01661 | Unannotated protein. (271 aa) |
| | GCA_001696535_01678 | Unannotated protein. (361 aa) |
| | hemH | Unannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (359 aa) |
| | GCA_001696535_01714 | Unannotated protein. (131 aa) |
| | purK | Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (367 aa) |
| | purE | Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa) |
| | GCA_001696535_01760 | Unannotated protein. (86 aa) |
| | GCA_001696535_01762 | Unannotated protein. (637 aa) |
| | GCA_001696535_01775 | Unannotated protein. (214 aa) |
| | GCA_001696535_01783 | Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (207 aa) |
| | purA | Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | GCA_001696535_01807 | Unannotated protein. (732 aa) |
| | rpoH | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (300 aa) |
| | FliI | Unannotated protein. (441 aa) |
| | GCA_001696535_01859 | Unannotated protein. (413 aa) |
| | GCA_001696535_01893 | Unannotated protein. (654 aa) |
| | GCA_001696535_01907 | Unannotated protein. (428 aa) |
| | GCA_001696535_01912 | Unannotated protein. (300 aa) |
| | GCA_001696535_01926 | Unannotated protein. (464 aa) |
| | GCA_001696535_01929 | Unannotated protein. (677 aa) |
| | GCA_001696535_01955 | Unannotated protein. (346 aa) |
| | GCA_001696535_01961 | Unannotated protein. (604 aa) |
| | fdhD-2 | Unannotated protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (271 aa) |
| | GCA_001696535_02074 | Unannotated protein. (283 aa) |
| | pyrD | Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate. (314 aa) |
| | pyrC | Unannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (349 aa) |
| | GCA_001696535_02091 | Unannotated protein. (818 aa) |
| | GCA_001696535_02103 | Unannotated protein. (166 aa) |
| | GCA_001696535_02118 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa) |
| | GCA_001696535_02157 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (177 aa) |
| | GCA_001696535_02163 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa) |
| | GCA_001696535_02225 | Unannotated protein. (161 aa) |
| | nbaC | Unannotated protein; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (180 aa) |
| | nadX | Unannotated protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (266 aa) |
| | GCA_001696535_02255 | Unannotated protein. (736 aa) |
| | GCA_001696535_02261 | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa) |
| | GCA_001696535_02304 | Unannotated protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa) |
| | GCA_001696535_02309 | Unannotated protein. (340 aa) |
| | upp | Unannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | GCA_001696535_02416 | Unannotated protein. (292 aa) |
| | ThiS | Unannotated protein. (65 aa) |
| | thiG | Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (257 aa) |
| | GCA_001696535_02420 | Unannotated protein. (200 aa) |
| | GCA_001696535_02422 | Unannotated protein. (242 aa) |
| | GCA_001696535_02425 | Unannotated protein. (218 aa) |
| | kynU | Unannotated protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (420 aa) |
| | CobA | Unannotated protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (481 aa) |
| | GCA_001696535_02478 | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa) |
| | GCA_001696535_02559 | Unannotated protein; Belongs to the ribF family. (333 aa) |
| | purD | Unannotated protein; Belongs to the GARS family. (428 aa) |
| | ctaB | Unannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (315 aa) |
| | GCA_001696535_02601 | Unannotated protein; Belongs to the UPF0301 (AlgH) family. (199 aa) |
| | amn | Unannotated protein; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (512 aa) |
| | atpB | Unannotated protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (252 aa) |
| | atpE | Unannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | atpF | Unannotated protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (188 aa) |
| | atpF-2 | Unannotated protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (159 aa) |
| | MoaB | Unannotated protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (185 aa) |
| | GCA_001696535_02638 | Unannotated protein. (185 aa) |
| | GCA_001696535_02651 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (177 aa) |
| | nadA | Unannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (361 aa) |
| | GCA_001696535_02654 | Unannotated protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. (542 aa) |
| | GCA_001696535_02655 | Unannotated protein; Belongs to the NadC/ModD family. (289 aa) |
| | GCA_001696535_02663 | Unannotated protein. (225 aa) |
| | ribB | Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (439 aa) |
| | dxs | Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa) |
| | apaG | Unannotated protein. (130 aa) |
| | pyrD-2 | Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (370 aa) |
| | GCA_001696535_02790 | Unannotated protein. (550 aa) |
| | GCA_001696535_02808 | Unannotated protein; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (449 aa) |
| | GCA_001696535_02892 | Unannotated protein. (329 aa) |
| | GCA_001696535_02893 | Unannotated protein. (576 aa) |
| | GCA_001696535_03200 | Unannotated protein. (272 aa) |
| | GCA_001696535_03269 | Unannotated protein. (187 aa) |
| | GCA_001696535_03287 | Unannotated protein; Belongs to the sigma-70 factor family. (296 aa) |
| | GCA_001696535_03318 | Unannotated protein. (157 aa) |
| | GCA_001696535_03320 | Unannotated protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (195 aa) |
| | CobW | Unannotated protein. (373 aa) |
| | CobN | Unannotated protein. (1257 aa) |
| | CobO | Unannotated protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (210 aa) |
| | cobQ | Unannotated protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (490 aa) |
| | cobD | Unannotated protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (327 aa) |
| | GCA_001696535_03326 | Unannotated protein. (339 aa) |
| | GCA_001696535_03349 | Unannotated protein. (460 aa) |
| | GCA_001696535_03352 | Unannotated protein. (439 aa) |
| | RfbC | Unannotated protein; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | GCA_001696535_03367 | Unannotated protein. (353 aa) |
| | RfbD | Unannotated protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (291 aa) |
| | GCA_001696535_03433 | Unannotated protein. (321 aa) |
| | GCA_001696535_03452 | Unannotated protein. (227 aa) |
| | GCA_001696535_03468 | Unannotated protein. (247 aa) |
| | GCA_001696535_03497 | Unannotated protein. (410 aa) |
| | GCA_001696535_03504 | Unannotated protein. (401 aa) |
| | bioB | Unannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa) |
| | GCA_001696535_03556 | Unannotated protein. (852 aa) |
| | dnaE2 | Unannotated protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1081 aa) |
| | GCA_001696535_03618 | Unannotated protein. (218 aa) |
| | GCA_001696535_03639 | Unannotated protein. (327 aa) |
| | GCA_001696535_03653 | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa) |
| | GCA_001696535_03654 | Unannotated protein; Belongs to the sigma-70 factor family. (311 aa) |
| | nadX-2 | Unannotated protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (266 aa) |
| | pdxH | Unannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (211 aa) |
| | nusA | Unannotated protein; Participates in both transcription termination and antitermination. (547 aa) |
| | GCA_001696535_03761 | Unannotated protein; Belongs to the KdsB family. (254 aa) |
| | dnaX | Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (653 aa) |
| | GCA_001696535_03774 | Unannotated protein. (549 aa) |
| | priA | Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (741 aa) |
| | atpH | Unannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (186 aa) |
| | atpA | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (509 aa) |
| | atpG | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa) |
| | atpD | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (479 aa) |
| | atpC | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | GCA_001696535_03818 | Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (372 aa) |
| | GCA_001696535_03827 | Unannotated protein. (561 aa) |
| | cmk | Unannotated protein. (208 aa) |
| | GCA_001696535_03880 | Unannotated protein. (692 aa) |
| | GCA_001696535_03890 | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (529 aa) |
| | QueG | Unannotated protein. (342 aa) |
| | nadD | Unannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (202 aa) |
| | proA | Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (426 aa) |
| | proB | Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (401 aa) |
| | GCA_001696535_03962 | Unannotated protein. (395 aa) |
| | GCA_001696535_03963 | Unannotated protein. (217 aa) |
| | GCA_001696535_03964 | Unannotated protein. (408 aa) |
| | GCA_001696535_03965 | Unannotated protein; Belongs to the precorrin methyltransferase family. (242 aa) |
| | CobJ | Unannotated protein. (606 aa) |
| | CobM | Unannotated protein. (261 aa) |
| | cobB | Unannotated protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (437 aa) |
| | GCA_001696535_03970 | Unannotated protein; Belongs to the precorrin methyltransferase family. (332 aa) |
| | cbiD | Unannotated protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (360 aa) |
| | GCA_001696535_03972 | Unannotated protein. (248 aa) |
| | GCA_001696535_03984 | Unannotated protein. (303 aa) |
| | GCA_001696535_03991 | Unannotated protein. (132 aa) |
| | GCA_001696535_04081 | Unannotated protein. (394 aa) |
| | purH | Unannotated protein. (538 aa) |
| | GCA_001696535_04155 | Unannotated protein; Belongs to the pyridoxine kinase family. (294 aa) |
| | accA | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | GCA_001696535_04161 | Unannotated protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (225 aa) |
| | folD | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa) |
| | GCA_001696535_04187 | Unannotated protein. (547 aa) |
| | Hpt | Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | GCA_001696535_04223 | Unannotated protein; Belongs to the Cob(I)alamin adenosyltransferase family. (191 aa) |
| | GCA_001696535_04228 | Unannotated protein. (412 aa) |
| | GCA_001696535_04264 | Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa) |
| | FolK | Unannotated protein. (169 aa) |
| | acsA | Unannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (646 aa) |
| | GCA_001696535_04290 | Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (235 aa) |
| | hemC | Unannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa) |
| | GCA_001696535_04317 | Unannotated protein; Belongs to the FPP/GGPP synthase family. (301 aa) |
| | GCA_001696535_04323 | Unannotated protein. (144 aa) |
| | GCA_001696535_04331 | Unannotated protein. (97 aa) |
| | GCA_001696535_04340 | Unannotated protein; Belongs to the sigma-70 factor family. (289 aa) |
| | fcl | Unannotated protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (326 aa) |
| | GCA_001696535_04351 | Unannotated protein; Belongs to the BolA/IbaG family. (100 aa) |
| | CobT | Unannotated protein. (630 aa) |
| | GCA_001696535_04372 | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa) |
| | GCA_001696535_04381 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (203 aa) |
| | rho | Unannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (421 aa) |
| | HemJ | Unannotated protein. (141 aa) |
| | hemE | Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa) |
| | coaE | Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (195 aa) |
| | dnaQ | Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (234 aa) |
| | trpF | Unannotated protein; Belongs to the TrpF family. (230 aa) |
| | trpB | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa) |
| | polA | Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (1003 aa) |
| | trpA | Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (276 aa) |
| | accD | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (327 aa) |
| | GCA_001696535_04467 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. (436 aa) |
| | coaA | Unannotated protein. (324 aa) |
| | pyrF | Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (249 aa) |
| | GCA_001696535_04503 | Unannotated protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (384 aa) |
| | MoeB | Unannotated protein. (268 aa) |
| | dut | Unannotated protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa) |
| | CoaBC | Unannotated protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa) |
| | PreA | Unannotated protein. (436 aa) |
| | HydA-2 | Unannotated protein. (485 aa) |
| | HemA | Unannotated protein. (406 aa) |
