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glmS glmS PuuA_2 PuuA_2 PuuA_1 PuuA_1 purA purA SFD56824.1 SFD56824.1 Sad Sad purQ purQ SFD58887.1 SFD58887.1 purF purF argG argG GltD GltD GltB_2 GltB_2 gabD gabD Ald_2 Ald_2 TyrB TyrB carA carA GlnII GlnII GdhA GdhA AraE_2 AraE_2 PutA_1 PutA_1 SFE08838.1 SFE08838.1 SFE09276.1 SFE09276.1 SFE10392.1 SFE10392.1 SFE10440.1 SFE10440.1 DgdA DgdA AraE_1 AraE_1 GlnA_2 GlnA_2 GlnA_1 GlnA_1 pyrB pyrB glsA glsA SFE36176.1 SFE36176.1 SFE31862.1 SFE31862.1 PutA_2 PutA_2 GabT GabT carB carB glnA glnA PurB PurB Tpa_4 Tpa_4 argH argH AnsB AnsB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (607 aa)
PuuA_2L-glutamine synthetase. (452 aa)
PuuA_1Glutamate--putrescine ligase; Belongs to the glutamine synthetase family. (438 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa)
SFD56824.1Serine-glyoxylate aminotransferase apoenzyme. (403 aa)
SadSuccinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase. (457 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (222 aa)
SFD58887.1Ornithine cyclodeaminase. (339 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (487 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa)
GltDGlutamate synthase (NADPH) small subunit. (478 aa)
GltB_2Glutamate synthase (NADPH) large subunit. (1510 aa)
gabDSuccinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (492 aa)
Ald_2L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. (372 aa)
TyrBAromatic amino acid aminotransferase apoenzyme. (394 aa)
carACarbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (382 aa)
GlnIIL-glutamine synthetase. (359 aa)
GdhAGlutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (477 aa)
AraE_2Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase. (475 aa)
PutA_1L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1221 aa)
SFE08838.1Aspartate aminotransferase. (406 aa)
SFE09276.1Hypothetical protein. (522 aa)
SFE10392.1Serine-glyoxylate aminotransferase apoenzyme. (396 aa)
SFE10440.1Ornithine cyclodeaminase. (321 aa)
DgdAAlanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
AraE_1Succinate semialdehyde dehydrogenase. (478 aa)
GlnA_2L-glutamine synthetase. (453 aa)
GlnA_1Glutamine synthetase. (492 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (317 aa)
glsAL-glutaminase; Belongs to the glutaminase family. (338 aa)
SFE36176.1Aspartate aminotransferase. (400 aa)
SFE31862.1Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. (398 aa)
PutA_2L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1144 aa)
GabT4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (474 aa)
carBCarbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1102 aa)
glnAL-glutamine synthetase. (468 aa)
PurBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa)
Tpa_44-aminobutyrate---pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
argHArgininosuccinate lyase. (463 aa)
AnsBL-asparaginase. (165 aa)
Your Current Organism:
Roseovarius indicus
NCBI taxonomy Id: 540747
Other names: CCTCC AB 208233, DSM 26383, LMG 24622, LMG:24622, MCCC 1A01227, R. indicus, Roseovarius indicus Lai et al. 2011, Roseovarius sp. B108, strain 2PR52-14, strain B108
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