STRINGSTRING
CUX76794.1 CUX76794.1 CUX76795.1 CUX76795.1 gcvPB gcvPB gcvPA gcvPA CUX76904.1 CUX76904.1 CUX76946.1 CUX76946.1 CUX77020.1 CUX77020.1 CUX77092.1 CUX77092.1 CUX77117.1 CUX77117.1 CUX77139.1 CUX77139.1 purC purC purF purF CUX77189.1 CUX77189.1 pyrC pyrC purS purS purQ purQ purL purL argG argG argH argH CUX77207.1 CUX77207.1 CUX77239.1 CUX77239.1 CUX77260.1 CUX77260.1 guaB guaB CUX77285.1 CUX77285.1 tdh tdh CUX77435.1 CUX77435.1 ilvD ilvD CUX77458.1 CUX77458.1 CUX77459.1 CUX77459.1 leuD leuD leuC leuC leuA leuA ilvC ilvC CUX77464.1 CUX77464.1 CUX77535.1 CUX77535.1 CUX77565.1 CUX77565.1 CUX77573.1 CUX77573.1 CUX77574.1 CUX77574.1 hcp hcp CUX77662.1 CUX77662.1 CHITON_0909 CHITON_0909 CUX77689.1 CUX77689.1 thrB thrB CUX77691.1 CUX77691.1 CUX77692.1 CUX77692.1 CUX77695.1 CUX77695.1 CUX77724.1 CUX77724.1 CUX77725.1 CUX77725.1 metE metE CUX77803.1 CUX77803.1 CUX77804.1 CUX77804.1 CUX77805.1 CUX77805.1 CUX77859.1 CUX77859.1 ahcY ahcY pyrB pyrB pyrI pyrI purM purM purT purT purE purE purK purK purD purD CUX78011.1 CUX78011.1 CUX78042.1 CUX78042.1 purA purA CUX78097.1 CUX78097.1 CUX78225.1 CUX78225.1 gcvT gcvT CUX78238.1 CUX78238.1 pyrE pyrE CUX78321.1 CUX78321.1 CUX78322.1 CUX78322.1 upp upp CUX78330.1 CUX78330.1 guaAB guaAB guaAA guaAA gcvH gcvH CUX78420.1 CUX78420.1 CUX78434.1 CUX78434.1 pyrH pyrH CUX78449.1 CUX78449.1 CUX78482.1 CUX78482.1 pyrD pyrD trpB trpB CUX78641.1 CUX78641.1 glyA glyA CUX78706.1 CUX78706.1 proC proC carB carB carA carA CUX78726.1 CUX78726.1 trpC trpC trpD trpD trpE trpE CUX78730.1 CUX78730.1 trpF trpF trpB-2 trpB-2 trpA trpA CUX78734.1 CUX78734.1 CUX78735.1 CUX78735.1 CUX78736.1 CUX78736.1 aroC aroC aroA aroA CUX78742.1 CUX78742.1 CUX78743.1 CUX78743.1 CUX78744.1 CUX78744.1 CUX78745.1 CUX78745.1 aroK aroK aroE aroE aroD aroD aroB aroB CUX78750.1 CUX78750.1 CUX78753.1 CUX78753.1 lysK lysK lysJ lysJ lysZ lysZ argC argC CUX78758.1 CUX78758.1 CUX78759.1 CUX78759.1 CUX78760.1 CUX78760.1 leuD-2 leuD-2 leuC-2 leuC-2 CUX78763.1 CUX78763.1 CUX78764.1 CUX78764.1 CUX78765.1 CUX78765.1 CUX78772.1 CUX78772.1 CUX78773.1 CUX78773.1 CUX78774.1 CUX78774.1 CUX78775.1 CUX78775.1 vapC-3 vapC-3 CUX78777.1 CUX78777.1 hisC hisC hisI hisI hisF hisF hisA hisA hisH hisH CUX78783.1 CUX78783.1 CUX78784.1 CUX78784.1 CUX78785.1 CUX78785.1 hisD hisD hisG hisG CUX78788.1 CUX78788.1 CUX78789.1 CUX78789.1 CUX78812.1 CUX78812.1 CUX78813.1 CUX78813.1 CUX78814.1 CUX78814.1 CUX78815.1 CUX78815.1 CUX78816.1 CUX78816.1 CUX78874.1 CUX78874.1 CUX78875.1 CUX78875.1 CUX78876.1 CUX78876.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CUX76794.1Glutamate synthase [NADPH] small chain. (476 aa)
CUX76795.1Hydrogenase, gamma chain (hydg). (290 aa)
gcvPBGlycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (502 aa)
gcvPAGlycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
CUX76904.1DNA-cytosine modification methylase MJ0563; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (299 aa)
CUX76946.1L-asparaginase I, cytoplasmic. (328 aa)
CUX77020.1Prephenate dehydratase. (273 aa)
CUX77092.1Glutaredoxin-like protein. (226 aa)
CUX77117.1Aromatic-amino-acid aminotransferase. (413 aa)
CUX77139.1Isoaspartyl aminopeptidase @ Asp-X dipeptidase. (305 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (235 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (442 aa)
CUX77189.1Dihydroorotate dehydrogenase electron transfer subunit. (237 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (414 aa)
purSPhosphoribosylformylglycinamidine synthase, PurS subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa)
purQPhosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (223 aa)
purLPhosphoribosylformylglycinamidine synthase, synthetase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (704 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (414 aa)
argHArgininosuccinate lyase. (430 aa)
CUX77207.1Lysine biosynthesis protein LysX. (274 aa)
CUX77239.1Xanthosine/inosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (184 aa)
CUX77260.12-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (395 aa)
guaBInosine-5'-monophosphate dehydrogenase / CBS domain; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
CUX77285.1Glutamate synthase [NADPH] large chain; Belongs to the glutamate synthase family. (502 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (348 aa)
CUX77435.1Aspartate racemase. (226 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (547 aa)
CUX77458.1(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (534 aa)
CUX77459.13-isopropylmalate dehydrogenase. (355 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (423 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). (498 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa)
CUX77464.1Acetolactate synthase large subunit. (562 aa)
CUX77535.1Homoserine dehydrogenase. (320 aa)
CUX77565.1Alkyl hydroperoxide reductase subunit C-like protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (216 aa)
CUX77573.1Glutamate synthase [NADPH] small chain. (475 aa)
CUX77574.1Dihydroorotate dehydrogenase electron transfer subunit. (283 aa)
hcpHydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (445 aa)
CUX77662.1Asparagine synthetase [glutamine-hydrolyzing]. (482 aa)
CHITON_0909Aspartate-semialdehyde dehydrogenase. (334 aa)
CUX77689.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (394 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (292 aa)
CUX77691.1Aspartokinase; Belongs to the aspartokinase family. (356 aa)
CUX77692.1Aspartokinase. (376 aa)
CUX77695.1Acetolactate synthase small subunit. (134 aa)
CUX77724.1Glutamate synthase [NADPH] small chain. (474 aa)
CUX77725.1Hydrogenase, subunit gamma related protein. (278 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. (337 aa)
CUX77803.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (309 aa)
CUX77804.1Function Code: 16.1 Conserved Hypothetical. (339 aa)
CUX77805.1Cystathionine gamma-synthase. (367 aa)
CUX77859.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (450 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (421 aa)
pyrBAspartate carbamoyltransferase. (308 aa)
pyrIAspartate carbamoyltransferase regulatory chain (PyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. (152 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (333 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (429 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (172 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (376 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (438 aa)
CUX78011.1Thioredoxin. (115 aa)
CUX78042.1L-threonine 3-O-phosphate decarboxylase. (321 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa)
CUX78097.1Glutamine synthetase type I. (439 aa)
CUX78225.1N-succinyl-L,L-diaminopimelate desuccinylase. (353 aa)
gcvTAminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. (398 aa)
CUX78238.1Arylmalonate decarboxylase. (236 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (182 aa)
CUX78321.1Sarcosine oxidase, subunit beta. (382 aa)
CUX78322.1Sarcosine oxidase, alpha subunit. (491 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (232 aa)
CUX78330.1Uracil permease. (427 aa)
guaABGMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP. (307 aa)
guaAAGMP synthase [glutamine-hydrolyzing], amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. (178 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (134 aa)
CUX78420.13'-phosphoadenosine 5'-phosphosulfate sulfotransferase. (427 aa)
CUX78434.1Thioredoxin reductase. (330 aa)
pyrHUridine monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (225 aa)
CUX78449.1Threonine synthase. (441 aa)
CUX78482.1Lipoate-protein ligase A. (250 aa)
pyrDDihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (323 aa)
trpBTryptophan synthase beta chain like; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (443 aa)
CUX78641.1Threonine synthase. (341 aa)
glyASerine hydroxymethyltransferase / H4MPt-dependent SHMT; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
CUX78706.1Adenine phosphoribosyltransferase, fused to N-terminal DNA-binding domain. (353 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1051 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (373 aa)
CUX78726.1Hypothetical protein. (224 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (228 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (324 aa)
trpEAnthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] (438 aa)
CUX78730.1Anthranilate synthase, amidotransferase component. (190 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (208 aa)
trpB-2Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (387 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (248 aa)
CUX78734.1Prephenate and/or arogenate dehydrogenase. (259 aa)
CUX78735.1Biosynthetic Aromatic amino acid aminotransferase alpha. (344 aa)
CUX78736.1Chorismate mutase I. (76 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (356 aa)
aroA5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (401 aa)
CUX78742.1Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1). (302 aa)
CUX78743.1Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1). (328 aa)
CUX78744.1Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1). (500 aa)
CUX78745.1Nucleoside ABC transporter, periplasmic nucleoside-binding protein. (422 aa)
aroKShikimate kinase II. (273 aa)
aroEShikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa)
aroD3-dehydroquinate dehydratase I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (212 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (334 aa)
CUX78750.12-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I beta. (263 aa)
CUX78753.1Hypothetical protein. (104 aa)
lysKN-acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. Belongs to the peptidase M20A family. LysK subfamily. (326 aa)
lysJN-acetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (369 aa)
lysZAcetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (249 aa)
argCN-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (330 aa)
CUX78758.1Lysine biosynthesis protein LysX. (273 aa)
CUX78759.1Lysine biosynthesis protein LysW. (55 aa)
CUX78760.1Homoisocitrate dehydrogenase. (345 aa)
leuD-2Homoaconitase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (163 aa)
leuC-2Homoaconitase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (380 aa)
CUX78763.1Homocitrate synthase. (359 aa)
CUX78764.1Transcriptional regulator, GntR family domain / Aspartate aminotransferase. (388 aa)
CUX78765.1Aspartate racemase. (227 aa)
CUX78772.1Hypothetical protein. (377 aa)
CUX78773.1Hypothetical protein. (196 aa)
CUX78774.1Hypothetical protein. (60 aa)
CUX78775.1Predicted hydrolase, HAD superfamily. (242 aa)
vapC-3Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (131 aa)
CUX78777.1Hypothetical protein. (92 aa)
hisCHistidinol-phosphate aminotransferase. (336 aa)
hisIPhosphoribosyl-AMP cyclohydrolase / Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. (207 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (238 aa)
hisHImidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa)
CUX78783.1Hypothetical protein. (285 aa)
CUX78784.1Hypothetical protein. (307 aa)
CUX78785.1Imidazoleglycerol-phosphate dehydratase. (176 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (376 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (204 aa)
CUX78788.1ATP phosphoribosyltransferase regulatory subunit. (291 aa)
CUX78789.1Uncharacterized protein MJ0754. (200 aa)
CUX78812.1Predicted transcriptional regulator with C-terminal CBS domain. (186 aa)
CUX78813.1Sarcosine oxidase alpha subunit. (475 aa)
CUX78814.1Putative polyferredoxin. (168 aa)
CUX78815.1Hypothetical protein. (86 aa)
CUX78816.1Sarcosine oxidase beta subunit. (375 aa)
CUX78874.1Glutamate synthase [NADPH] small chain. (348 aa)
CUX78875.13-oxoacyl-[acyl-carrier protein] reductase. (259 aa)
CUX78876.1Hypothetical protein. (153 aa)
Your Current Organism:
Thermococcus chitonophagus
NCBI taxonomy Id: 54262
Other names: DSM 10152, T. chitonophagus, strain GC74
Server load: low (30%) [HD]